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Components of he Cardiovascular System
Blood
Capillaries
Arteries
Heart
Veins
Blood Vessels
Capillaries
Allow for substances to move between cells and blood
Vein
Carries blood towards heart
Artery
Carries blood away from heart
Left Heart
Pumps blood to heart
Receives oxygenated blood from lungs
Right Heart
Receives deoxygenated blood from body
Pumps blood to lungs
Pulmonary Circulation Steps
Superior Vena Cava, inferior vena cava and coronary sinus deliver blood to right atrium
Blood crosses R atrioventricular valve
Blood enters R Ventricle
Blood crosses pulmonary semilunar valve
Blood enters Pulmonary Trunk
Blood enters R and L Pulmonary Arteries
Blood enters R and L lungs
Blood enters pulmonary capillaries
Blood is oxygenated
Blood enters R and L pulmonary veins
Blood enters Left Atrium
Systemic Circulation Steps
Blood enters Left Atrium
Blood crosses L atrioventricular valve
Blood enters L ventricle
Blood crosses aortic valve
Blood enters aorta
Blood enters systemic artery
Nutrients delivered
Deoxygenated blood enters systemic veins
Blood enters SVC, IVC, and Coronary Sinus
Blood enters R atrium
Right Atrium
Heart chamber that receives deoxygenated blood from body
Aorta
Carries blood from Left ventricle to body
Left Ventricle
Heart chamber that pumps blood to body
Right Atrioventricular Valve
Controls blood flow between the Right atrium and Left ventricle
Pulmonary Semilunar Valve
Controls blood flow between right ventricle and lungs
Tendinous Cords
Heart strings; connect papillary muscle to atrioventricular valves
Pulmonary capillaries
allows for oxygen to enter blood
Pulmonary arteries
carries blood from right ventricle to lungs
Papillary muscle
muscles in ventricular wall that control the atrioventricular valve
myocardium
middle layer of heart wall; contains cardiac muscle that pumps blood
inferior vena cava
carries blood from lower body to right atrium
left atrioventricular valve
controls blood flow between left atrium and left ventricle
Pulmonary Veins
Carries blood from lungs to left atrium
Left Atrium
heart chamber that receives oxygenated blood
Right Ventricle
Heart chamber that pumps blood to lungs
Aortic Semilunar Valve
Controls blood flow between left ventricle and aorta
Endocardium
Innermost later of the heart wall
Intercalculated Discs
Cellular connection of the heart muscle that provide both mechanical and electrical connections
Coronary Sinus
Carries blood from the heart tissue to right atrium
Superior Vena Cava
Carries blood from upper body to the right atrium
Q-T Interval
Time it takes for an action potential to move through ventricles
P Wave
Atrial Depolarization
Q-T Segment
Time when ventricles contract
P- R Interval
Time it takes for an action potential to move through an entire conduction system
T Wave
Ventricular Repolarization
QRS Complex
Ventricular Depolarization
P-Q Segment
Time when atria is contracting
Atrial Relaxation/Ventricular Filling
Ventricles relax and open the atrioventricular valves
Isovolumetric Contraction
Ventricles contract enough to close the atrioventricular valves but not open the semilunar valves; blood remains in ventricles
Ventricular Ejection
Left ventricle pumps blood into the aorta; Rightventricle pumps blood into the pulmonary trunk
Isovolumetric Relaxation
Ventricle Relaxes and closes semilunar valves
Atrial Contraction and Ventricular Filling
Left atrium pumps blood into the left ventricle; right atrium pumps blood. into the right ventricle
Preload
Amount of stretch in heart wall prior to contraction
Cardiac Output
Amount of blood pumped by one ventricle in one minute
Chronotropic Agents
Substances capable of changing heart rates
Cardiac Reserve
Increase in cardiac output above resting level
Contractibility
Force of heart contraction
Edema
Swelling
Afterload
Resistance in arteries to ejection of blood by ventricles
Venous Return
Amount of blood the veins return to heart
Heart Rate
Number of beats per minute
Ventricular Balances
Left ventricle and Right ventricle pump equal amounts of blood
Inotropic Agents
Substances capable of altering heart contractibility
Stoke Volume
Cardiac Output = Stoke Volume x Heart Rate
Systole
Heart Chamber Contraction
Cardiac Cycle
Inclusive changes within heart from initiation of one heartbeat to beginning of the next
Conductivity
Process of an action potential moving down the sarcolemma
Diastole
Heart Chamber Relaxation
Atrial Reflex
Automatic response keeps heart from over filling
Perfusions
Delivery of blood per unit of time per gram of tissue
Tetany
Sustained muscle contraction that leads to muscle fatigue
Refractory Period
Time when muscle cannot contract
Vasa Vasorum
Small arteries that supply blood flow to large blood vessels
Tunica Media
Smooth Muscle
Tunica Interna
Simple Squamous Epithelium
Tunica Externa
Areolar Connective Tissue
Arterial Anastomoses
Many arterioles lead to one single capillary bed
Portal System
Vein enters a second capillary bed before draining into a second bed
Arteriovenous Anastomoses
Arteriole drains directly into a venule
Venous Anastomoses
Many venules draining into a single capillary bed
Cross Sectional Area
Diameter of vessel’s lumen
Blood Flow
How fast blood moves through a vessel
Total Cross Sectional Area
Sum of all cross sectional area for a given blood vessel type
Reabsorption
Bulk flow movement into venous end of capillary
Hydrostatic Pressure
Physical Force exerted by a Fluid on a structure
Filtration
Bulk flow movement out of a capillary’s artery end
Bulk Flow
Movement of large amounts of fluids and their dissolved substances in one direction down a pressure gradient
Osmotic Pressure
High concentration of solutes pulling water into an area
Net Filter Pressure
Formula that compares hydrostatic and osmotic pressures to determine whether a capillary will do filtration or reabsorption
Myogenic Response
Contraction or relaxation of smooth muscle in tunica media to regulate blood flow to a tissue
Angiogenesis
Formation of new blood vessels
Autoregulation
When a tissue can alter blood flow on its own based on metabolic needs
Vasodilation
Relaxes smooth muscle in tunica media; increases blood flow
Vasocontriction
Contraction of smooth muscle in tunica media; decreases blood flow
Vascularization
Number of blood vessels in a tissue
Blood pressure Gradient
Change in blood pressure from one end of vessel to other end
Diastolic Pressure
Lowest Pressure
Pulse Pressure
Additional pressure placed on arteries when heart is resting
Mean Arterial Pressure
Average pressure in arteries
Systolic Pressure
Highest Pressure when the arterial wall is maximally stretched due to ventricular contraction
Blood Pressure
Force that blood exerts on a blood vessel wall
Pulse Pressure Formula
Systolic Blood Pressure - Diastolic Blood Pressure
Mean Arterial Pressure Formula
Diastolic Blood Pressure + 1/3 Pulse Pressure
Peripheral Resistance
Obstacles to blood flow
Respiratory Pumps
Using inhalation and exhalation to move blood towards the heart
Skeletal Muscle Pump
Using skeletal muscle contractions to move blood towards heart
Venous Return
Blood getting from veins to heart
Umbilical Veins
Carries oxygenated blood to fetus
Umbilical Arteries
Carries deoxygenated blood from fetus to placenta
Ductus Arteriosus
A fetal blood vessel that connects the pulmonary trunk to aorta
Ductus Venosus
Fetal blood vessel that connects liver to inferior vena cava
Foramen Ovale
An opening that connects the right atrium to the left atrium of fetal heart