Anti Cancer meds

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8 Terms

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Cyclophosphamide

Alkylating agent; cytotoxic; non–cell cycle specific; risk of bone marrow suppression.

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Cisplatin

Platinum compound; cytotoxic; non–cell cycle specific; nephrotoxicity, ototoxicity.

3
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Methotrexate (Cancer)

Antimetabolite; folic acid analog; S-phase specific; risk of mucositis, myelosuppression

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Fluorouracil (5-FU)

Antimetabolite; pyrimidine analog; S-phase specific; kills dividing cells only

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Vincristine

Mitotic inhibitor; M-phase specific; neurotoxicity, constipation

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Tamoxifen

Hormonal agent; estrogen receptor blocker; used in breast cancer; endometrial cancer risk; only used for 5 years

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Leuprolide

Hormonal agent; suppresses gonadal hormones; prostate/breast cancer; causes bone pain

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Ondansetron (Zofran)

Antiemetic; prevents chemo-induced nausea/vomiting; risk of QT prolongation