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2 body systems of regulation
nervous and endocrine
rapid response and short duration
nervous
slow response and long duration
endocrine
nerve cell - basic unit of structure and function, transmits electrochemical signals
neuron
cell body- maintains cell
soma
receive signal
dendrites
signal travels ?
axon to terminal, d-s-a
neurons maintain a ( ) charge ( ) by pumping sodium ions out and potassium ions in
(-) (resting potential)
if dendrites are excited up to ( ), nerve fires ( ) ; sends ( ) down axon
- all or no response
(threshold potential) (depolarizes) (action potential)
recharge period .0005s
refractory period/ repolarization
speeds transmission of signal down axon, limits ability to rewire connections
Myelin
progressive loss of myelin, slow transmission
MS
gap between neurons
synapse
firing neuron releases ( ) from axon terminals - may excite or inhibit- or maybe be broken down in synapse or drift back to the sender to be reused
(neurotransmitters)
mood, attention, movement ect.
- high = schizophrenia
low = parkinsons
dopamine
mood, sleep, sex, appetite ect.
- high= vomiting, coma, death
low= depression, ocd
serotonin
mucle contraction, memory
- high= convulsions, ridgid paralysis
low= alzheimers, flaccid paralysis
acetylcholine (ACh)
attention, flight or fight response
- low= adhd, depression
norepinephrine
sleep, selective attention
- inhibitory
-low= anxiety
GABA
handmade (in yo body) morphine
- blocks pain- mood, sleep, pleasure, sex
endorphins
mimic nt
agonist
keep NTs in synapse so they keep working
reuptake inhibitors
increase NT effectivness or amount
Promoters
makes them last longer
breakdown inhibitors
block receptors
antagonist
brain and spinal cord
consists of interneurons
central nervous system (CNS)
peripheral nervous system
- neurons receive signals from receptors, send info to CNS
Afferent (sensory)
peripheral nervous system
- neurons carry instructions from CNS to muscles, glands
efferent (motor)
peripheral nervous system
motor divisions:
controls voluntary muscles
- reflex arc
somatic
peripheral nervous system
motor divisions:
controls glands, heart, smooth muscles
- flight or fight response
autonomic
sympathetic division of autonomic NS
- prepares the body for action
- adrenal gland releases epinephrine
- heat rate, perspiration, respiration increases
- pupils dilate
- blood to muscles, digestion slows
parasympathetic division restores homeostasis
flight or fight response
tools of brain study
observation
autopsy
lesions
electrical/magnetic stimulation
over all electrical activity
EEG- electroencephalogram
series of x rays- shows sections of brain, physical structures
cat- computerized axial tomography
detects glucose consumption
pet- positron emission tomography
shows physical structures including soft tissue
MRI- Magnetic resonance imaging
detects blood flow as well as physical structures including soft tissue
fmri- functional magnetic resonance imaging
-less than 2 pounds
-100 billion neurons
connect up to 10000 others
brain facts
myelinated axons
white matter
mostly somae and dendrites
gray matter
three layers of tissue surrounding the brain and spinal cord
meninges
cushions and protects the brain
cerebrospinal fluid (CSF)
( ) in brain have thicker, less permeable walls
capillaries
prevents most poisons, infections, drugs and immune system components from reaching the brain
blood- brain barrier
reptilian brain or hindbrain
brain stem
brain stem
- heart rate, basic automatic functions
medulla oblongata
brain stem
- switching area for control of body, dreams, respiration
pons
inside brainstem
-alertness, arousal
reticular formation
motor control, balance, muscle memory
cerebellum
thalamus
hypothalamus
the limbic system
midbrain/ mammalian brain
switching area for all senses, except smell
thalamus
drives hunger thirst and sex; controls endocrine system
hypothalamus
the limbic system
emotion
limbic
fear and rage
amygdala
limbic
pleasure habit and routine ect
basal ganglia
limbic
memory
hippocampus
human brain
cerebral cortex/ neocortex
30 billion neurons with 10000 synapses each
250 billion glial cells support feed and produce myelin and guide new connections
two hempispheres
human brain
connects 2 hemispheres- composed of 250 million axons
corpus callosum
each hemisphere has 4 lobes
frontal parietal temporal occipital
judgment
planning
problem solving
controlling and executing behavior
contains motor cortex
over all maturity
frontal lobe
spatial relations/ orientation
memory of faces and spaces
contains sensory cortex aka somatosensory cortex
- sense of touch
parietal lobe
mostly taken up my visual cortex
involved with memory
association areas
occipital lobe
contains auditory cortex
involved with memory
association areas
temporal lobe
areas of brain without dedicated function can be activated for many purposes
association areas
specialization of cerebral hemispheres
some individual variation exists
about 1/3 of left handed people have reversed specialization
hemispheric lateralization
humor
right
empathy
right
episodic memory
right
pattern recognition
right
wholistic problem solving; insight
right
spatial relations
right
control of left side
right
music
right
control of right
left
language
left
sequential problem solving; logic
left
chronology; cause and effect
left
arithmetic
left
attention to detail
left
rationalization
left
big picture (forest)
right
details (trees)
left
impaired use of language
aphasia
left frontal lobe, produces speech
broca's area
broca's aphasia
expressive
left temporal lobe, processes meaning, build/ interprets sentences
wernicke's area
wernicke's aphasia
receptive
left parietal lobe converts visual into auditory (reading)
angular gyrus
severed to treat epilepsy
corpus callosum
can point and draw with left hand
cannot name, point or draw with right
left visual field
ability of brain to change/ reassign functions
decreases with age
plasticity
white matter and brainstem
not plastic
cortex regions with dedicated functions
limited plasticity
association areas
greater plasticity
visual cortex > touch and hearing
blind
auditory cortex > vision
deaf
age 25 had a tamping iron damage frontal lobe
resulted in
blind in one eye
limp
poor planning ability
intense moods and emotions
not himself
phineas gage
glands secrete hormones
long term regulation
endocrine system
pineal gland
hypothalamus
pituitary
thyroid
adrenal
pancreas
gonads
endocrine glands