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Gestational Age (GA)
Time from the first day of the last menstrual period used to estimate fetal age; postconceptual age is GA minus 2 weeks.
Last Menstrual Period (LMP)
Date used as the starting point to calculate gestational age.
Postconceptual Age / Embryonic Age
Age from conception; equals GA minus 2 weeks.
Full Term
37–42 weeks GA; 40 weeks is commonly used for calculation.
Chronological Age
Days, weeks, or months since birth.
Premature
Birth that occurs before 37 weeks GA.
Corrected (Adjusted) Age
Chronological age minus the number of weeks born prematurely.
Zygote
Fertilized egg; initial stage after conception.
Blastocyst
Early embryo stage before implantation.
Endoderm
Germ layer that gives rise to the digestive tract.
Mesoderm
Germ layer that forms muscles, skeleton, and circulation.
Ectoderm
Germ layer that forms skin and the nervous system.
Neural Tube Closure
Process by which the neural tube closes; critical between Weeks 4–8; defects can cause neural tube defects.
Anencephaly
Absence of the cranial vault; incompatible with life.
Craniorachischisis
Open cranium and spine due to failure of neural tube closure.
Open Spina Bifida
Spinal defect with incomplete fusion of the vertebrae; neural tissue may be exposed.
Encephalocele
Sac-like protrusion of brain tissue through a skull defect.
Omphalocele
Herniation of abdominal contents at the base of the umbilical cord.
Teratogens
Agents (drugs, chemicals, infections, maternal conditions) capable of causing developmental abnormalities.
Critical Periods of Development
Windows during which teratogens can cause specific birth defects or abnormalities.
Prevention of Birth Defects
Early prenatal care; folic acid supplementation (400 mcg daily) before/during pregnancy; avoid smoking, alcohol, and harmful substances.
Folic Acid (400 mcg)
Supplement started before pregnancy to help prevent neural tube defects.
Fetal Alcohol Syndrome (FAS)
Birth defects caused by prenatal alcohol exposure; may include facial features, growth deficiencies, and CNS problems.
Neonatal Abstinence Syndrome (NAS)
Withdrawal symptoms in newborns after abrupt cessation of gestational exposure to substances.
Apgar Score
Neonatal assessment at 1 and 5 minutes evaluating color, heart rate, reflexes, muscle tone, and respiration; ranges guide needed interventions.
Small for Gestational Age (SGA)
Birth weight less than the 10th percentile for gestational age.
Low Birth Weight (LBW)
Birth weight 2500 g (5 lb 8 oz) or less.
Very Low Birth Weight (VLBW)
Birth weight 1500 g (3 lb 5 oz) to less than 1500 g.
Extremely Low Birth Weight (ELBW)
Birth weight less than 1000 g.
Breech Birth
Birth presentation where the buttocks or feet come first instead of the head.
Vertex
Head-down fetal presentation — normal vaginal delivery possibility.
Lanugo
Fine prenatal body hair often present in mid-gestation.
Surfactant
Lung fluid that reduces surface tension; production begins around 24 weeks and matures near late gestation.
Viability
Ability of the fetus to survive outside the womb, generally around 23 weeks gestation with intensive care.
Quickening
Maternal perception of fetal movements, typically in the 17–20 weeks of gestation.