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Drugs can affect coagulation and haemostasis by acting on __________.
What are antithrombotic agents?
Medications used to prevent or treat thrombosis by inhibiting blood clot formation.
Name three classes of antithrombotic agents.
Antiplatelet agents, anticoagulants, and thrombolytics.
What is the primary action of thrombolytics?
To dissolve existing blood clots.
Common side effects of anticoagulants include __________.
bleeding and bruising.
What is the mechanism of action for antiplatelet agents?
They inhibit platelet activation and aggregation.
How does Warfarin function as an anticoagulant?
By inhibiting vitamin K-dependent clotting factors.
What role does Heparin play in anticoagulation?
It enhances the activity of antithrombin III, leading to increased inhibition of thrombin and factor Xa.
Examples of thrombolytic agents include __________ and __________.
Alteplase and Reteplase.
What is the antidote for Warfarin overdose?
Vitamin K.
What is the importance of monitoring INR levels in patients on Warfarin?
To prevent bleeding complications and ensure safe therapeutic levels.