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Flashcards generated from the Introduction to Neurosciences - Student MCQ Test.
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Which glial cells is primarily responsible for forming myelin in the CNS?
Oligodendrocytes
Which type of neuron primarily carries information from the periphery to the central nervous system?
Sensory neurons
Which type of neuron is responsible for connecting and synchronizing signals between neurons?
Interneurons
What is the role of astrocytes in the nervous system?
Form the blood-brain barrier and provide metabolic support
Which glial cell type is involved in immune defense and phagocytosis of debris in the CNS?
Microglia
In radiological imaging, what best describes the axial plane?
Parallel to the floor of the cranium
Which structure connects the two hemispheres of the brain?
Corpus callosum
What is the primary function of the cerebellum?
Motor coordination and learning
Which pathway is responsible for discriminative touch?
Dorsal column-medial lemniscus
Which disease is characterized by the loss of dopamine-producing neurons in the substantia nigra?
Parkinson's disease
What is the main function of the thalamus?
Relay station for sensory information
The pyramidal tract primarily controls:
Voluntary motor control
What is the typical resting membrane potential of a neuron?
-70 mV
What maintains the resting membrane potential?
Potassium leak channels
During the depolarization phase of an action potential, which ion enters the neuron?
Na+
Which of the following best describes saltatory conduction?
Jumping of action potentials between nodes of Ranvier
Which ion is most permeable in the resting neuron membrane?
K+
What is the role of the Na+/K+ pump in neurons?
Maintains ion gradients across the membrane
Which neurotransmitter is the main excitatory neurotransmitter in the CNS?
Glutamate
Which receptor type produces the fastest postsynaptic response?
Ionotropic receptor
What happens during long-term potentiation (LTP)?
Strengthening of synaptic transmission due to high-frequency stimulation
What causes GABA to be excitatory in the developing brain?
Higher intracellular chloride concentration
Which receptor is blocked by magnesium at rest but activated when depolarized?
NMDA receptor
Spike-timing dependent plasticity (STDP) is based on:
Precise timing of presynaptic and postsynaptic activity
Which mechanoreceptor in glabrous skin detects texture and shape?
Merkel cells
Which mechanosensitive ion channel is crucial in proprioception?
Piezo2
What sensory information does the spinothalamic pathway carry?
Pain and temperature
What condition results from frataxin mutation and affects proprioception?
Friedreich's ataxia
Which brain area maps sensory input and shows cortical magnification?
Primary somatosensory cortex
What type of afferents coil around the central part of intrafusal fibers?
Group Ia
Which cells in the retina are responsible for phototransduction?
Photoreceptors
In darkness, what is the state of the photoreceptor membrane?
Depolarized due to open cGMP-gated Na+ channels
What pigment is found in rods?
Rhodopsin
Which type of ganglion cell responds to light in the center of its receptive field?
On-center cell
What structure contains the auditory sensory receptors?
Organ of Corti
Which ion enters hair cells during sound transduction?
K+
Which membrane vibrates first in response to sound waves?
Tympanic membrane
How is pitch (frequency) encoded in the auditory system?
By position of maximal vibration on basilar membrane
Which structure detects vertical acceleration?
Saccule
What ion is responsible for depolarizing vestibular hair cells?
K+
Which canal detects nodding motion (yes gesture)?
Superior
Where do vestibular signals project to adjust posture and eye movements?
Brainstem and cerebellum
Olfactory receptors are what type of receptors?
G-protein coupled receptors
Where is the olfactory epithelium located?
Superior nasal cavity
What does cAMP do in olfactory signal transduction?
Opens Na+ channels
Which brain area does olfactory information reach directly?
Primary olfactory cortex
Which ions are involved in the ionotropic transduction of salty and sour tastes?
Na+ and H+
Which tastes are detected by metabotropic receptors?
Bitter, sweet, and umami
Where do second-order gustatory neurons project?
Limbic system and thalamus
What is the initial event in taste transduction?
Binding of gustatory molecules to microvilli