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General senses
skin, viscera
Special senses
eyes, ears, nose, tongue
Sensation
brain aware
Perception
brain interprets
Projection
sensation - from receptors
Adaptation
ignore stimuli
repeated, unimportant
Touch
skinÂ
Fine touch (epithelium)
tactile (meissner’s) corpuscles
tactile discs/merkel cells
root hair plexusÂ
Pressure, stretch (dermis)
lamellate (pacinian) corpuscles
ruffini corpuscles
Itch
free nerve endings
Warm receptors
25-45 degrees C (77-113F)
Cold receptors
10-20 degrees C (50-68F)
Pain - free nerve endings
mech damage, extreme temp, chemicals
not brain
do not adapt
type A vs type C fibers
Regulation
enkephalins, endorphins
Visceral pain
internal organs
referred pain
common pathwayÂ
Proprioception body position
skeletal muscle tension
Proprioception muscle spindles
muscle/tendon junction
stretch - stimulation
stretch reflex
Proprioception golgi tendon organs
increased tension - stimulation
prevent excess contractionÂ
Smell
olfactory receptors
Chemoreceptors
upper nasal cavity
Olfactory epithelium
olfactory receptor cell
cilia
odorants
olfactory glands
mucusÂ
Basal cells
stem
Odorants
gas - dissolve in mucous
Impulse generation
odorant - CAMP
Na+ depol
Impulse pathÂ
olfactory bulb
olfactory code
olfactory tract
limbic system
memoryÂ
Pheromones
scent signals
attraction
mate selection
reproductive cycles
Taste
tongue
Lingual papillae circumvallate
100 taste buds
Lingual papillae fungiform
5 taste buds
Lingual papillae filliform
friction
Gustatory cell
modified epithelium
receptor
taste hairs
receptive
taste pore
basal cell
Chemical dissolve - saliva
bind to hairs
Primary tastes
sweet
sour
salty
bitter
umamiÂ
water
calcium
Sweet, sour
chem gate channels
Salty, bitter, umami
2nd messenger
Water
pharynx
Taste
sensation tied with smell
Light refraction
bending
pass through
differing density
Convex lensÂ
converge light
cornea (75%)
lensÂ
Concave lens
diverge light
Image - retina
upside down
reversed
Accommodation
distance - affects light
More distance
20ft converge
Less distance
20ft difficult
change lens shapeÂ
Ciliary body
contracts
ligaments relax
lens thickensÂ
Myopia
near
long eye
concave
Hyperopia
far
short eye
convex
Retina light path backward
ganglion cells
bipolar cells
horizontal/amacrine cells
» modify
photoreceptors
pigmented epitheliumÂ
Rods
low light
BW
blurryÂ
Cones
high light
color
red, blue, greenÂ
Retina photoreceptors distribution
not uniformÂ
Rods distribution
periphery
Cones distribution
fovea centralis
macula lutea
blind spotÂ
Retina photoreceptors structure
discs
» photopigment
rhodopsinÂ
opsin
retinalÂ
Visual pigments rods rhodopsin
opsin
retinal (A)
» dark = bent
Visual pigments rods light
retinal = straight
loses attachment
bleached
impulse is bipolar - ganglionÂ
Visual pigments cones photopsin
work as rods
higher threshold
Visual pigments cones colors
erythrolabe
chlorolabe
cyanolabeÂ
Visual pigments
color perceptionÂ
Visual pigments overlap
cones and rods
Light adaptation - darkness to light
rhodopsin bleached
glare
cones take over
60s
Dark adaptation - light to dark
cones stop
but, rods bleached
restore rhodopsin
slowÂ
Binocular vision
overlap fields
2 eyes
depthÂ
Hearing
sound path
Sound =
vibrations
Ear
air - bone - fluid
Sound path enters…
outer ear. auricle, external acoustic meatus, tympanic membrane
External acoustic meatus
ceruminous glands
Tympanic membrane
vibrates
Sound path transferred…
to middle ear
Ear ossicles (M, I, S)
vibrate
amplifyÂ
Stapes
oval window
inner ear
fluid vibrationÂ
Auditory tube
equalize
Inner ear labyrinth bony
perilymph
Inner ear labyrinth membranous
endolymphÂ
Semicircular canals
vestibule
Cochlea
bony, membrane
Scali vestibuli (P)
oval window
vestibular membrane
Cochlear duct (E)
organ of corti
Scali tympani (P)
basilar membrane
Organ of corti
hair cells - 4 rows. kinocilium, sterocilia
tectorial membraneÂ
Stapes - oval window
scali vestibuli (P)
vestibular membrane
Cochlear duct (E)
basilar membrane
bends hairs
impulseÂ
Scali tympani
round window
Sound path cochlea frequency
different area
basilar membraneÂ
Equilibrium vestibule
utricle, saccule
macula
hair cellsÂ
Equilibrium body position
still
Hairs
otolithic membrane
statoconia (otoliths)
Gravity
sagging
hairs bend = impulseÂ
Dynamic
sudden movement
macula
fallingÂ
Rotation
semicircular canals
Three planes
anterior
posterior
lateralÂ
Membranous canals
fluid
ampulla
crista ampullarisÂ
Crista ampullaris
hair cells
cupulaÂ
What happens during rotation?
endolymph moves
cupula bends
hair cells
impulseÂ