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General senses
skin, viscera
Special senses
eyes, ears, nose, tongue
Sensation
brain aware
Perception
brain interprets
Projection
sensation - from receptors
Adaptation
ignore stimuli
repeated, unimportant
Touch
skin
Fine touch (epithelium)
tactile (meissner’s) corpuscles
tactile discs/merkel cells
root hair plexus
Pressure, stretch (dermis)
lamellate (pacinian) corpuscles
ruffini corpuscles
Itch
free nerve endings
Warm receptors
25-45 degrees C (77-113F)
Cold receptors
10-20 degrees C (50-68F)
Pain - free nerve endings
mech damage, extreme temp, chemicals
not brain
do not adapt
type A vs type C fibers
Regulation
enkephalins, endorphins
Visceral pain
internal organs
referred pain
common pathway
Proprioception body position
skeletal muscle tension
Proprioception muscle spindles
muscle/tendon junction
stretch - stimulation
stretch reflex
Proprioception golgi tendon organs
increased tension - stimulation
prevent excess contraction
Smell
olfactory receptors
Chemoreceptors
upper nasal cavity
Olfactory epithelium
olfactory receptor cell
cilia
odorants
olfactory glands
mucus
Basal cells
stem
Odorants
gas - dissolve in mucous
Impulse generation
odorant - CAMP
Na+ depol
Impulse path
olfactory bulb
olfactory code
olfactory tract
limbic system
memory
Pheromones
scent signals
attraction
mate selection
reproductive cycles
Taste
tongue
Lingual papillae circumvallate
100 taste buds
Lingual papillae fungiform
5 taste buds
Lingual papillae filliform
friction
Gustatory cell
modified epithelium
receptor
taste hairs
receptive
taste pore
basal cell
Chemical dissolve - saliva
bind to hairs
Primary tastes
sweet
sour
salty
bitter
umami
water
calcium
Sweet, sour
chem gate channels
Salty, bitter, umami
2nd messenger
Water
pharynx
Taste
sensation tied with smell
Light refraction
bending
pass through
differing density
Convex lens
converge light
cornea (75%)
lens
Concave lens
diverge light
Image - retina
upside down
reversed
Accommodation
distance - affects light
More distance
20ft converge
Less distance
20ft difficult
change lens shape
Ciliary body
contracts
ligaments relax
lens thickens
Myopia
near
long eye
concave
Hyperopia
far
short eye
convex
Retina light path backward
ganglion cells
bipolar cells
horizontal/amacrine cells
» modify
photoreceptors
pigmented epithelium
Rods
low light
BW
blurry
Cones
high light
color
red, blue, green
Retina photoreceptors distribution
not uniform
Rods distribution
periphery
Cones distribution
fovea centralis
macula lutea
blind spot
Retina photoreceptors structure
discs
» photopigment
rhodopsin
opsin
retinal
Visual pigments rods rhodopsin
opsin
retinal (A)
» dark = bent
Visual pigments rods light
retinal = straight
loses attachment
bleached
impulse is bipolar - ganglion
Visual pigments cones photopsin
work as rods
higher threshold
Visual pigments cones colors
erythrolabe
chlorolabe
cyanolabe
Visual pigments
color perception
Visual pigments overlap
cones and rods
Light adaptation - darkness to light
rhodopsin bleached
glare
cones take over
60s
Dark adaptation - light to dark
cones stop
but, rods bleached
restore rhodopsin
slow
Binocular vision
overlap fields
2 eyes
depth
Hearing
sound path
Sound =
vibrations
Ear
air - bone - fluid
Sound path enters…
outer ear. auricle, external acoustic meatus, tympanic membrane
External acoustic meatus
ceruminous glands
Tympanic membrane
vibrates
Sound path transferred…
to middle ear
Ear ossicles (M, I, S)
vibrate
amplify
Stapes
oval window
inner ear
fluid vibration
Auditory tube
equalize
Inner ear labyrinth bony
perilymph
Inner ear labyrinth membranous
endolymph
Semicircular canals
vestibule
Cochlea
bony, membrane
Scali vestibuli (P)
oval window
vestibular membrane
Cochlear duct (E)
organ of corti
Scali tympani (P)
basilar membrane
Organ of corti
hair cells - 4 rows. kinocilium, sterocilia
tectorial membrane
Stapes - oval window
scali vestibuli (P)
vestibular membrane
Cochlear duct (E)
basilar membrane
bends hairs
impulse
Scali tympani
round window
Sound path cochlea frequency
different area
basilar membrane
Equilibrium vestibule
utricle, saccule
macula
hair cells
Equilibrium body position
still
Hairs
otolithic membrane
statoconia (otoliths)
Gravity
sagging
hairs bend = impulse
Dynamic
sudden movement
macula
falling
Rotation
semicircular canals
Three planes
anterior
posterior
lateral
Membranous canals
fluid
ampulla
crista ampullaris
Crista ampullaris
hair cells
cupula
What happens during rotation?
endolymph moves
cupula bends
hair cells
impulse