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Flashcards for Fat and Protein Metabolism Oxidation
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Glycerol
Carried in blood dissolved as it is soluble in plasma as it has 3 OH group attached.
FFAs
Carried in the blood attached to protein albumin as they are not soluble in aqueous plasma.
Free fatty acids
Also called non esterified fatty acids (NEFA)
Transport of Fatty Acids to the muscle
Fats move through the blood via lipoproteins (triglycerides) or bound to the protein.
Lipid Metabolism Step 1
Breakdown of triglyceride Free Fatty Acids
Lipid Metabolism Step 2
Transport of FFA in the blood (attached to albumin)
Lipid Metabolism Step 3
Uptake FFA from the blood to muscle
Lipid Metabolism Step 4
Preparation of FA for a catabolism (Energy activation)
Lipid Metabolism Step 5
Entry of activated FA into muscle mitochondria
Lipid Metabolism Step 6
Breakdown of FA to acetyl-CoA via oxidation and the production of NADH and FADH2
Ketone Bodies production
Excess acetyl-CoA is converted to ketone bodies because not enough pyruvate is produced to maintain CAC cycle intermediates (Oxaloacetate)
Transamination
Transfer of amino group i.e. the nitrogen group to ketoregulate
Glucogenesis
Blood glucose must be maintained for brain function
Glycogen
The body’s storage of carbohydrate
Glycogenolysis
glycogen breakdown