Syndrome of inappropriate antidiuretic hormone

endocrine conditions

dx labs of Syndrome of inappropriate antidiuretic hormone

• serum osmolality. dilutional hyponatremia is indicated by a serum sodium level of less than 134 mmol/L, serum osmolality of less than 280 mmol/k

• simultaneous measurements of urine

monitoring labs of Syndrome of inappropriate antidiuretic hormone

• sodium levels decline (dilutional hyponatremia)

nursing interventions for Syndrome of inappropriate antidiuretic hormone

Rationale for the intervention

• monitor BP for hypertension

• hypertonic less than 9% saline gets the fluid out of the extracellular space and into the vascular system.

• assess for crackles lung sounds difficulty breathing

• before admin diuretics check potassium lv before giving next dose of the loop diuretics

• fluid I/O

tx of Syndrome of inappropriate antidiuretic hormone

If symptoms are mild and the serum sodium level exceeds 125 mmol/L, the only treatment may be fluid restriction (between 800 and 1 000 mL/day).

• This restriction should result in gradual daily weight reduction, a progressive rise in serum sodium concentration and osmolality

• fluid restriction (800 to 1 000 mL/day). decrease thirst

• Ice chips or

• sugarless chewing gum meds take at meals to prevent Gi irritation

• diuretic to remove excess fluid volume, and

• well-diluted sodium and potassium supplements

• declomycin

• hypertonic less than 9% saline gets the fluid out of the extracellular space and into the vascular system.

meds that cause syndrome of antidiuretic hormone

meds that cause siadh • Antineoplastic agents (vincristine, vinblastine, cyclophosphamide [Procytox]) • Carbamazepine (Tegretol) • Chlorpropamide • General anaesthetic agents • Opioids • Oxytocin • SSRI antidepressants • Thiazide diuretics • Tricyclic antidepressants Miscellaneous Conditions • Adrenal insufficiency • Chronic obstructive pulmonary disease • HIV infection • Hypothyroidism • Lung infection (pneumonia, tuberculosis, lung abscess) • Positive pressure mechanical ventilation