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Dendrites
Receive incoming messages
Cell Body (soma)
Contains the nucleus
Myelin Sheath
Fatty tissue that insulates axon, speeding up transmission of the message
Node of Ranvier
Space between myelin sheath
Axon
Longest part of the neuron which electrical messages travel the length of
Schwann Cells
Non-neuronal cells in the CNS that form myelin sheath
Axon Terminal Buds
The end point pod a neuron that releases neurotransmitters into the synapse; sending the message to the next neuron
Resting Potential
when a neuron is not firing and has a negative charge with mostly potassium ions inside and mostly sodium ions on the outside
Polarization
at resting potential when sodium is on the outside, potassium on the inside of a neuron
Action Potential
Nerve impulse - causes the neuron to fire
All-or-nothing principle
when the nucleus decides to fire, it fires down the axon completely or not at all
intensity
strength/power of message
depolarization
when message begins, sodium ions come in & depolarize (neutralize) section of axon. Like a domino effect, Na ions rush in causing K ions to flush out
refractory period
potassium ions were previously pushed out and neuron “pauses to reload”
Neurotransmitters
chemical substance that causes the synapse to carry on the message to the next neuron
Synapse
open space between the neurons at which neurtransmitters cross
Acetylcholine
Muscle contractions, memory & learning (Alzheimers)
Dopamine
Movement, thought process, rewarding sensation (Parkinson, schizophrenia, drug addiction)
Serotonin
Emotion states, sleep (depression)
Norepinephrine
Physical arousal, learning and memory (depression, stress)
GABA
inhibition of brain activity (anxiety)
Endorphines
Pain perception, positive emotions, “runners high” (opiate addiction)
Glutamine
Excitatory neurotransmitters; involved in memory. overstimulate brain, produce migraine or seizures
Substance P
Regulates bone & cartilage metabolism & fracture healing. Sickle cell disease, IBS, fibromyalgia, reduce pain sensitivity and stability of bones
Agonist transmitters
Mimic neurotransmitter activity, fits in receptor site like a master key
Antagonist transmitters
Blocks neurotransmitter activity, fills in receptor site like a fake key
Peripheral nervous system (PNS)
sensory and motor neurons that connect CNS to the rest of the body
Central Nervous System
Contains spine and brain in the center of the body
Autonomic PNS
Controls involuntary functions
Somatic PNS
controls voluntary movements and communication to an from the sensory organs
Sympathetic autonomic pns
physically arouses the body, flight or flight
parasympathetic autonomic pns
calms the body, rest and digest
Interneurons
only neurons n CNS acting as messengers between sensory and motor neurons
sensory (afferent) interneurons
carries incoming messages from the sense receptors to the cns
Motor (efferent) neurons
carries outgoing information from the ins to the peripheral nervous system and muscles
Endocrine system
communicates with the brain using chemical messages, hormones
Hormones
released into and circulate through the bloodstream, received only at a specific site
Pituitary gland
“master gland” directed by the hypothalamus, sends out hormone singles to other glands
Thyroid Gland
produces hormone thyroxine - stimulates chemicals important to all body tissues, regulate metabolism, physical growth & development, and calcium rate
Adrenal gland
release epinephrine and norepinephrine - help individuals generate extra energy to deal with difficult situations; regulate fight or flight and metabolism
Gonads (sex glands)
testes - release testosterone
ovaries - release estrogen and progesterone
regulate body development and maintain reproductive organs in adults
Electroencephalograph (EEG)
monitors electrical activity of the brain over time by means of recording electrodes attached to the surface of the scalp
CT Scan
Computerized Tomography Scan, computer enhanced x-ray of brain structure, multiple x rays shot, combines images to make vivid horizontal slice of brain, least expensive, used to look for abnormalities in brain
MRI
Uses magnetic fields, radio waves, & computerized enhancements to map out brain structure
fMRI
consists of several variations of MRI technology that monitory blood and oxygen flow in the brain to identify areas of high activity, provides structural & functioning information in the same image, monitors brain activity in real time
Lesioning
destroying a piece of brain tissue
electrical stimulation of brain (ESB)
sending weak electric current into a brain structure to activate it, delivered through electrode, but current is different, close but doesn’t duplicate normal signals
PET Scan
mapping out actual activity in the brain over time. radioactively tagged chemicals introduced into brain, serve as markers for blood flow or metabolic activity. color coded map, monitored by x rays
brainstem
part of the brain with longest ancestry, even most simple creatures have this part of the brain. connects to the spinal cord, made of medulla, pons, reticular formation, thalamus
Hindbrain
structures on top of spinal cord. controls basic biological structures
Medulla oblongata
located just above spinal cord, great rate breathing, blood pressure. operates on autopilot without conscious awareness, like most of brainstem
Pons
Located just above the medulla, connects hindbrain, midbrain, and forebrain together, maintains sleep-wake cycle, involved in controlling facial expressions
Cerebellum
Bottom rear of the brain - “little brain” coordinates fine muscle & body movements, like tracking a target.
Midbrain
coordinates simple movements with sensory info, contains the reticular formation: arousal and ability to focus attention.
Forebrain
makes us human, largest part of the brain made up of the thalamus, limbic system, and cerebral cortex
thalamus
in forebrain, receives sensory info & sends to appropriate areas of forebrain, like a switch board, everything except smell
Limbic System
Emotional Control Center of brain
Hypothalamus
Pea sized in brain, controls body temp, hunger, thirst, sexual arousal (libido), endocrine system (directs pituitary gland)
Medical forebrain bundle (MFB)
runs between the ventral segmental area (VTA) and lateral hypothalamus.
Hippocampus
involved in learning and memory processing
amygdala
vital for basic emotions, more involved in volatile emotions like anger, aggression, anxiety, and fear
Cerebral cortex
Top layer of brain, contains wrinkles called fissures, fissure increase surface area of brain, made up of “gray matter” - densely packed neurons responsible for information processing
Glial Cellcs
support brain cells
White matter
highway that consists of large networks of nerve fibers that allow information to pass to all the different regions of brain
Anterior frontal lobe
prefrontal cortex, very important for “higher cognitive functions” and determination of the personality
Posterior frontal lobe
consists of premotor and motor areas
areas of cerebral cortex
divided into eight lobes, four in each hemisphere (frontal, parietal, occipital and temporal
Association areas
any area not dealing with senses or muscle movements
frontal lobe
abstract thought and emotional control, contains motor cortex for controlling muscle movements, and broca’s area for controlling muscles that produce speech. damage to broca’s area is Broca’s aphasia, causes broken speech
parietal lobes
contain (somato) sensory cortex, receives incoming touch sensations from rest of the body, mostly made up of association areas
motor cortex
left hemisphere section controls body right side
sensory cortex
left hemisphere section receives input from body right side
occipital lobes
in back of head, handles visual input from eyes. lateralized - predominantly on one side, right half of each retina goes to left occipital lobe and vice versa. contains visual cortex, interprets messages from eyes into images
temporal lobes
processes sound sensed by ears & interpreted in auditory cortex. not lateralized. contains wernickes area - part of left temporal love: involved in understanding meaning of words; interprets written n spoken speech
wernickes aphasia
unable top understand language: the syntax n gammer; person is able to speak fluently and pronounce entirely wrong words correctly.
spatial/unilateral neglect
condition produced by damage to the right parietal and occipital lobes, results in an inability to recognize objects or body parts in the left visual field
hemispheres
divided into left and right, contralateral controlled - left controls right side of body and vice versa
corpus callosum
attaches the two hemispheres of cerebral cortex, when removed you have a split brain patient.
left hemisphere
specializes in language, speech, handwriting, calculation, sense of time and rhythm, and thought analysis
right hemisphere
specializes in processing involving perceptions like visual and spatial perception, recognition of patterns, faces, emotions, melodies, expression of emotions, and comprehension of simple language
reticular formation
network of neurons in brainstem, controls sleep-wake cycle and alertness/attention
psychoactive drugs
chemical substance that alters perceptions and mood. drugs that are small enough to pas through blood brain barrier
blood-brain barrier
semi permeable membrane within brain capillaries
physical dependence
physiological need for a drug, marked with withdrawal symptoms
negative reinforcement
tendency to continue a behavior that leads to the removal of or escape from unpleasant circumstances or sensations
psychological dependence
psychological need to use a drug to alleviate negative emotions
reward pathway
nucleus accumbent (motivation and goal-directed behavior) + ventral segmental area (dopamine production) + dopamine = intense pleasure
tolerance
diminished effect with regular use, body begins to stop naturally producing these chemicals
withdrawal
discomfort and distress that follow discontinued use
depressants
drugs that reduce neural activity, slow body functions. alcohol, barbiturates, opiates
stimulants
drugs that excite neural activity, speed up body functions. caffeine, nicotine, amphetamines, cocaine
hallucinogens
psychedelic (mind-manifesting) drugs that distort perceptions and evoke sensory images in the absence of sensory input. LSD
barbiturates
depress activity of cos, reducing anxiety but impairing memory and judgment
alcohol
most commonly used and abused depressant, health risks to liver, brain, and heart, indirectly stimulates the release of gaba which is the brains major depressant
opiates
plant-based substance, opium, depress neural activity, temporarily lessening pain and anxiety, mimics effects of endorphins, the nervous systems natural painkillers,
morphine
created by dissolving opium in an acid then neutralizing acid with ammonia, still used to control severe pain, in controlled doses for very short periods.
heroin
derivative of morphine, does not have many of the disagreeable side effects of morphine
amphetamines
synthesized in labs, crystal meth is a crystalline form, smoked and used by recreational drug users, results in short term energy and euphoria, eventually reduces baseline dopamine level, leaving user permanently depressed.
amphetamine psychosis
condition causing addicts to become delusional and paranoid; think ppl are out to get them; violence is a likely outcome against self and others
synesthesia
neuropsychological trait in which the stimulation of one sense causes the automatic experience of another sense