Pharmacology Ch. 11 Review

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Health

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94 Terms

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1) Hypertension is characterized by an increase in .

the systolic and/or diastolic blood pressure

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2) Which category of drugs promotes the excretion of sodium and water in the urine to lower the blood pressure?

diuretic drugs

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3) If the serum cholesterol level is too high, bile acid sequestrant drugs .

bind with bile to form an insoluble complex that is excreted in the feces

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4) Nitrate drugs .

dilate the coronary arteries and increase the flow of oxygenated blood to the heart muscle

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5) To decrease the pain of angina pectoris, beta-blocker drugs .

decrease the heart rate, which decreases the myocardium's need for oxygen

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6) When the drug atropine is used to treat bradycardia, its action is to .

block acetylcholine receptors in the heart so that the heart rate increases

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7) Beta-blocker drugs used to treat hypertension block all beta receptors in the heart and keep them from binding to .

epinephrine

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8) drugs relax smooth muscle in the walls of the arteries, cause the arteries to dilate, and are used to treat hypertension.

Peripheral vasodilator

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9) Calcium channel blocker drugs block the movement of calcium ions into the heart muscle and smooth muscles in the blood vessels. This results in all of the following, EXCEPT .

lowering the cholesterol level

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10) In addition to being used to treat hypertension and angina pectoris, the beta-blocker drug propranolol (Inderal) is also used to do all of the following, EXCEPT .

treat digitalis drug toxicity

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11) All of these substances are part of the body's own natural blood pressure-regulating system, EXCEPT .

triglycerides

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12) James Raucher has had asthma since he was a child. When he turned 60, he also developed hypertension. His physician prescribed a cardioselective beta-blocker drug to treat his hypertension because cardioselective beta-blocker drugs .

are better than other beta-blocker drugs in keeping the bronchi open and treating patients with hypertension and lung disease

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13) Which of the following statements is FALSE?

The two trade names of digoxin are Lopid and Lanoxin.

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14) The ending is common to generic beta-blocker drugs.

-olol

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15) Which of the following is a digitalis drug used to treat congestive heart failure?

digoxin (Lanoxin)

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16) What is the trade name of the generic beta-blocker drug propranolol?

Inderal

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17) The generic drug used to treat congestive heart failure is .

digoxin

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18) All of the following are trade name calcium channel blocker drugs, EXCEPT .

Xylocaine

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19) All of the following trade name drugs are used to treat an elevated level of cholesterol, EXCEPT .

Lanoxin

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20) The trade names for nitroglycerin include all of the following, EXCEPT .

Zocor

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21) An elevated level of cholesterol in the blood can be due to .

all of the above

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22) Nitroglycerin is available in all of the following drug forms, EXCEPT .

inhaled powder

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23) All of the following are beta-blocker drugs, EXCEPT .

hydralazine (Apresoline)

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24) An elevated level of triglycerides can be caused by all of the following, EXCEPT .

excessive dietary intake of meat

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25) The trade name for the antiarrhythmic generic drug lidocaine is .

Xylocaine

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26) Which of the following drugs is NOT an ACE inhibitor drug used to treat hypertension?

telmisartan (Micardis)

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27) Types of cardiac arrhythmias include all of the following, EXCEPT

hyperlipidemia

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28) Which of the following statements is TRUE concerning digitalis drugs?

all of the above

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29) Symptoms of digitalis toxicity include all of the following, EXCEPT .

a myocardial infarction

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30) All of the following trade name drugs are used to treat an elevated level of cholesterol, EXCEPT .

Lopressor

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31) Which of the following does NOT belong to the drug category of calcium channel blockers?

prazosin (Minipress)

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32) How are symptoms of digitalis toxicity treated?

all of the above

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33) drugs are also known as "statin drugs."

HMG-CoA reductase inhibitor drugs

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34) Drugs used to treat angina pectoris include all of the following, EXCEPT .

antiarrhythmic drugs

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35) Suzi Choi is a professional golfer. She takes a beta-blocker drug to help ease the performance anxiety she feels when she has to play in front of large crowds or in a televised golf tournament. The beta-blocker drug relieves all of the following symptoms, EXCEPT .

arrhythmias

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36) Very low-density lipoproteins carry in the blood.

triglycerides

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37) Which of the following is a combination drug that contains two drugs that both lower the serum cholesterol level?

Vytorin

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38) All of the following categories of drugs are used to treat congestive heart failure, EXCEPT .

"statin drugs"

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39) HDL, LDL, and VLDL are .

types of lipoproteins, carrier molecules or A and B

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40) Lifestyle changes are the first treatment recommended for which of the following diseases?

hypertension, hyperlipidemia or B and C

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41) The well-known generic name drug rosuvastatin that is used to treat hypercholesterolemia is related to the trade name drug .

Crestor

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42) Over-the-counter, low-dose, 81-mg tablets of this anticoagulant drug are taken daily by patients with heart disease who have had a heart attack or stroke.

aspirin

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(T/F) Hyperlipidemia is a category that includes both hypercholesterolemia and hypertriglyceridemia.

True

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(T/F) HMG-CoA reductase inhibitor drugs block HMG-CoA reductase, an enzyme that is involved in the production of cholesterol in the body.

True

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(T/F) A high level of HDL is undesirable

False

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(T/F) By blocking an enzyme, ACE inhibitor drugs cause blood vessels to dilate, and this decreases the blood pressure.

True

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(T/F) In patients with angina pectoris, anticoagulant drugs and thrombin inhibitor drugs are prescribed to prevent a blood clot that would cause a myocardial infarction.

True

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(T/F) Drugs that are used to treat ventricular fibrillation are also used when the heart has already stopped beating (cardiac arrest).

False

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(T/F) Alcoholic beverages contain sugar that is converted into triglycerides by the body.

True

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Digitalis drugs have a positive inotropic effect in treating congestive heart failure because they cause a stronger, more forceful contraction of the heart muscle cells.

True

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The pain of angina pectoris occurs when heart muscle cells die.

False

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(T/F) All beta receptors are stimulated by the hormone epinephrine in response to stress or danger.

True

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In 1967 when it was approved by the FDA, propranolol became the first drug in the beta-blocker category.

True

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(T/F) After a myocardial infarction, drugs can be given to improve heart function and reverse the cells that have died.

False

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(T/F) Chris Zanzone has just discovered that he has hyperlipidemia. Drug therapy, not lifestyle changes, is the first choice of treatment for hyperlipidemia.

False

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(T/F) The suffix -sartan is common to generic angiotensin II receptor blocker drugs.

True

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(T/F) Alpha-1-blocker drugs are used to treat hypertension because they block alpha1 receptors located in the arteries and veins.

True

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(T/F) HMG-CoA reductase inhibitor drugs are used to treat hypercholesterolemia.

True

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Digitalis drugs often causes toxicity because they have a short half-life.

False

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(T/F) Oatmeal in the diet is an effective way to reduce the cholesterol level of the blood.

True

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(T/F) Nesiritide (Natrecor), a drug used to treat congestive heart failure, is manufactured from E. coli bacteria, using recombinant DNA technology.

True

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(T/F) Bile acid sequestrant drugs are used to treat the pain of angina pectoris.

False

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(T/F) Inderide is a combination drug that contains the beta-blocker drug propranolol and the diuretic drug hydrochlorothiazide.

True

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(T/F) The American Heart Association recommends eating fish and taking fish oil supplements that contain omega-3 fatty acids to reduce cholesterol and triglyceride levels.

False

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(T/F) Normal blood pressure is defined as 120/80 mm Hg.

True

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(T/F) All generic HCG-CoA reductase inhibitor drugs have a common ending of -statin.

True

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(T/F) Oatmeal can lower the cholesterol in the blood because its oat fiber binds to bile and keeps it from being reabsorbed into the blood.

True

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The abbreviation HTN stands for .

Hypertension

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Diuretic drugs used to treat hypertension do this by promoting the excretion of and water in the urine, which lowers the blood pressure.

sodium

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To be transported through the blood, cholesterol and triglycerides must bind to certain carrier molecules, which are known as .

Lipoproteins

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drugs are also known as cardiac glycoside drugs because they have a molecular structure that consists of chains of glucose sugar known as glycosides.

Digitalis

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is the most frequently prescribed nitrate drug used to treat angina pectoris.

nitroglycerin

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The generic drug used to treat ventricular fibrillation and that is also used as an anesthetic drug is known as lidocaine and its trade name is .

Xylocaine

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Hypertension is caused by arteriosclerosis or kidney failure, but hypertension has no identifiable cause.

Essential

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Beta receptors located in the are designated as beta1 receptors.

heart

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Combination drugs used to treat hypertension often contain the diuretic drug hydrochlorothiazide, and this is shown because the trade name of the drug contains the abbreviation __.

HCT

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Cholesterol is produced by the and also comes from dietary intake from foods.

Liver

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Digoxin immune Fab, which is used to treat digitalis toxicity, is an antigen-binding fragment drug obtained from that have been treated to produce antibodies against the molecular structure of the drug digoxin.

Sheep

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The peripheral vasodilator drug minoxidil is used to treat hypertension, but it is also used topically under the trade name Rogaine to treat .

Thinning hair and baldness

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The abbreviation HTN stands for .

Hypertension

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The abbreviation ACE stands for .

angiotensin-converting enzyme

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The phrase stepped-care approach is related to the treatment of __.

Hypertension

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The well-known generic beta-blocker drug propranolol is related to the trade name drug .

Inderal

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The phrase "statin drugs" brings to mind the category of drugs used to treat high _.

Cholesterol

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diltiazem (Cardizem)

Calcium Channel blocker

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hydralazine (Apresoline)

Peripheral vasodilator

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losartan (Cozaar)

angiotensin II receptor blocker drug

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propranolol (Inderal)

beta-blocker drug

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quinapril (Accupril)

ACE inhibitor

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adenosine (Adenocard)

ventricular tachycardia

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lidocaine (Xylocaine)

ventricular fibrillation

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atropine

bradycardia

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digoxin (Lanoxin)

atrial flutter and fibrillation

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isoproterenol (Isuprel)

heart block