Pharmacology Ch. 11 Review

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  1. Hypertension is characterized by an increase in ________.

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Health

11th

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1
  1. Hypertension is characterized by an increase in ________.

the systolic and/or diastolic blood pressure

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2
  1. Which category of drugs promotes the excretion of sodium and water in the urine to lower the blood pressure?

diuretic drugs

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3
  1. If the serum cholesterol level is too high, bile acid sequestrant drugs ________.

bind with bile to form an insoluble complex that is excreted in the feces

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4
  1. Nitrate drugs ________.

dilate the coronary arteries and increase the flow of oxygenated blood to the heart muscle

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5
  1. To decrease the pain of angina pectoris, beta-blocker drugs ________.

decrease the heart rate, which decreases the myocardium's need for oxygen

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6
  1. When the drug atropine is used to treat bradycardia, its action is to ________.

block acetylcholine receptors in the heart so that the heart rate increases

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7
  1. Beta-blocker drugs used to treat hypertension block all beta receptors in the heart and keep them from binding to ________.

epinephrine

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8
  1. ________ drugs relax smooth muscle in the walls of the arteries, cause the arteries to dilate, and are used to treat hypertension.

Peripheral vasodilator

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9
  1. Calcium channel blocker drugs block the movement of calcium ions into the heart muscle and smooth muscles in the blood vessels. This results in all of the following, EXCEPT ________.

lowering the cholesterol level

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10
  1. In addition to being used to treat hypertension and angina pectoris, the beta-blocker drug propranolol (Inderal) is also used to do all of the following, EXCEPT ________.

treat digitalis drug toxicity

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11
  1. All of these substances are part of the body's own natural blood pressure-regulating system, EXCEPT ________.

triglycerides

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12
  1. James Raucher has had asthma since he was a child. When he turned 60, he also developed hypertension. His physician prescribed a cardioselective beta-blocker drug to treat his hypertension because cardioselective beta-blocker drugs ________.

are better than other beta-blocker drugs in keeping the bronchi open and treating patients with hypertension and lung disease

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13
  1. Which of the following statements is FALSE?

The two trade names of digoxin are Lopid and Lanoxin.

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14
  1. The ending ________ is common to generic beta-blocker drugs.

-olol

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15
  1. Which of the following is a digitalis drug used to treat congestive heart failure?

digoxin (Lanoxin)

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16
  1. What is the trade name of the generic beta-blocker drug propranolol?

Inderal

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17
  1. The generic drug used to treat congestive heart failure is ________.

digoxin

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18
  1. All of the following are trade name calcium channel blocker drugs, EXCEPT ________.

Xylocaine

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19
  1. All of the following trade name drugs are used to treat an elevated level of cholesterol, EXCEPT ________.

Lanoxin

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20
  1. The trade names for nitroglycerin include all of the following, EXCEPT ________.

Zocor

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21
  1. An elevated level of cholesterol in the blood can be due to ________.

all of the above

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22
  1. Nitroglycerin is available in all of the following drug forms, EXCEPT ________.

inhaled powder

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23
  1. All of the following are beta-blocker drugs, EXCEPT ________.

hydralazine (Apresoline)

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24
  1. An elevated level of triglycerides can be caused by all of the following, EXCEPT ________.

excessive dietary intake of meat

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25
  1. The trade name for the antiarrhythmic generic drug lidocaine is ________.

Xylocaine

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26
  1. Which of the following drugs is NOT an ACE inhibitor drug used to treat hypertension?

telmisartan (Micardis)

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27
  1. Types of cardiac arrhythmias include all of the following, EXCEPT ________

hyperlipidemia

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28
  1. Which of the following statements is TRUE concerning digitalis drugs?

all of the above

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29
  1. Symptoms of digitalis toxicity include all of the following, EXCEPT ________.

a myocardial infarction

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30
  1. All of the following trade name drugs are used to treat an elevated level of cholesterol, EXCEPT ________.

Lopressor

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31
  1. Which of the following does NOT belong to the drug category of calcium channel blockers?

prazosin (Minipress)

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32
  1. How are symptoms of digitalis toxicity treated?

all of the above

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33
  1. ________ drugs are also known as "statin drugs."

HMG-CoA reductase inhibitor drugs

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34
  1. Drugs used to treat angina pectoris include all of the following, EXCEPT ________.

antiarrhythmic drugs

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35
  1. Suzi Choi is a professional golfer. She takes a beta-blocker drug to help ease the performance anxiety she feels when she has to play in front of large crowds or in a televised golf tournament. The beta-blocker drug relieves all of the following symptoms, EXCEPT ________.

arrhythmias

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36
  1. Very low-density lipoproteins carry ________ in the blood.

triglycerides

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37
  1. Which of the following is a combination drug that contains two drugs that both lower the serum cholesterol level?

Vytorin

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38
  1. All of the following categories of drugs are used to treat congestive heart failure, EXCEPT ________.

"statin drugs"

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39
  1. HDL, LDL, and VLDL are ________.

types of lipoproteins, carrier molecules or A and B

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40
  1. Lifestyle changes are the first treatment recommended for which of the following diseases?

hypertension, hyperlipidemia or B and C

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41
  1. The well-known generic name drug rosuvastatin that is used to treat hypercholesterolemia is related to the trade name drug ________.

Crestor

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42
  1. Over-the-counter, low-dose, 81-mg tablets of this anticoagulant drug are taken daily by patients with heart disease who have had a heart attack or stroke.

aspirin

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43

(T/F) Hyperlipidemia is a category that includes both hypercholesterolemia and hypertriglyceridemia.

True

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44

(T/F) HMG-CoA reductase inhibitor drugs block HMG-CoA reductase, an enzyme that is involved in the production of cholesterol in the body.

True

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45

(T/F) A high level of HDL is undesirable

False

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46

(T/F) By blocking an enzyme, ACE inhibitor drugs cause blood vessels to dilate, and this decreases the blood pressure.

True

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47

(T/F) In patients with angina pectoris, anticoagulant drugs and thrombin inhibitor drugs are prescribed to prevent a blood clot that would cause a myocardial infarction.

True

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48

(T/F) Drugs that are used to treat ventricular fibrillation are also used when the heart has already stopped beating (cardiac arrest).

False

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49

(T/F) Alcoholic beverages contain sugar that is converted into triglycerides by the body.

True

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50

Digitalis drugs have a positive inotropic effect in treating congestive heart failure because they cause a stronger, more forceful contraction of the heart muscle cells.

True

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51

The pain of angina pectoris occurs when heart muscle cells die.

False

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52

(T/F) All beta receptors are stimulated by the hormone epinephrine in response to stress or danger.

True

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53

In 1967 when it was approved by the FDA, propranolol became the first drug in the beta-blocker category.

True

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54

(T/F) After a myocardial infarction, drugs can be given to improve heart function and reverse the cells that have died.

False

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55

(T/F) Chris Zanzone has just discovered that he has hyperlipidemia. Drug therapy, not lifestyle changes, is the first choice of treatment for hyperlipidemia.

False

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56

(T/F) The suffix -sartan is common to generic angiotensin II receptor blocker drugs.

True

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57

(T/F) Alpha-1-blocker drugs are used to treat hypertension because they block alpha1 receptors located in the arteries and veins.

True

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58

(T/F) HMG-CoA reductase inhibitor drugs are used to treat hypercholesterolemia.

True

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59

Digitalis drugs often causes toxicity because they have a short half-life.

False

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60

(T/F) Oatmeal in the diet is an effective way to reduce the cholesterol level of the blood.

True

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61

(T/F) Nesiritide (Natrecor), a drug used to treat congestive heart failure, is manufactured from E. coli bacteria, using recombinant DNA technology.

True

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62

(T/F) Bile acid sequestrant drugs are used to treat the pain of angina pectoris.

False

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63

(T/F) Inderide is a combination drug that contains the beta-blocker drug propranolol and the diuretic drug hydrochlorothiazide.

True

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64

(T/F) The American Heart Association recommends eating fish and taking fish oil supplements that contain omega-3 fatty acids to reduce cholesterol and triglyceride levels.

False

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65

(T/F) Normal blood pressure is defined as 120/80 mm Hg.

True

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66

(T/F) All generic HCG-CoA reductase inhibitor drugs have a common ending of -statin.

True

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67

(T/F) Oatmeal can lower the cholesterol in the blood because its oat fiber binds to bile and keeps it from being reabsorbed into the blood.

True

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68

The abbreviation HTN stands for ________.

Hypertension

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69

Diuretic drugs used to treat hypertension do this by promoting the excretion of ________ and water in the urine, which lowers the blood pressure.

sodium

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70

To be transported through the blood, cholesterol and triglycerides must bind to certain carrier molecules, which are known as ________.

Lipoproteins

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71

________ drugs are also known as cardiac glycoside drugs because they have a molecular structure that consists of chains of glucose sugar known as glycosides.

Digitalis

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72

________ is the most frequently prescribed nitrate drug used to treat angina pectoris.

nitroglycerin

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73

The generic drug used to treat ventricular fibrillation and that is also used as an anesthetic drug is known as lidocaine and its trade name is ________.

Xylocaine

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74

Hypertension is caused by arteriosclerosis or kidney failure, but ________ hypertension has no identifiable cause.

Essential

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75

Beta receptors located in the ________ are designated as beta1 receptors.

heart

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76

Combination drugs used to treat hypertension often contain the diuretic drug hydrochlorothiazide, and this is shown because the trade name of the drug contains the abbreviation __________.

HCT

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77

Cholesterol is produced by the ________ and also comes from dietary intake from foods.

Liver

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78

Digoxin immune Fab, which is used to treat digitalis toxicity, is an antigen-binding fragment drug obtained from ________ that have been treated to produce antibodies against the molecular structure of the drug digoxin.

Sheep

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79

The peripheral vasodilator drug minoxidil is used to treat hypertension, but it is also used topically under the trade name Rogaine to treat ________.

Thinning hair and baldness

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80

The abbreviation HTN stands for ________.

Hypertension

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81

The abbreviation ACE stands for ________.

angiotensin-converting enzyme

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82

The phrase stepped-care approach is related to the treatment of __________.

Hypertension

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83

The well-known generic beta-blocker drug propranolol is related to the trade name drug ________.

Inderal

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84

The phrase "statin drugs" brings to mind the category of drugs used to treat high _______.

Cholesterol

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85

diltiazem (Cardizem)

Calcium Channel blocker

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86

hydralazine (Apresoline)

Peripheral vasodilator

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87

losartan (Cozaar)

angiotensin II receptor blocker drug

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88

propranolol (Inderal)

beta-blocker drug

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89

quinapril (Accupril)

ACE inhibitor

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90

adenosine (Adenocard)

ventricular tachycardia

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91

lidocaine (Xylocaine)

ventricular fibrillation

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92

atropine

bradycardia

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93

digoxin (Lanoxin)

atrial flutter and fibrillation

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94

isoproterenol (Isuprel)

heart block

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