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What is Biological Evolution?
○ Any change in the inherited traits of a population that occurs from one generation to the next.
What are the four key components to the Biological Evolution definition?
○ Any Change
○ Inherited traits
○ Population
○ One generation to the next
What is the goal of evolutionary biology?
○ Understand the historical perspective of how the natural world came to be
What is an ultimate explanation?
○ Focuses on historical perspective of how something came to be
What is a proximate explanation?
○ Focuses on mechanistic understanding of how something happened
What are some practical benefits to studying biological evolution?
○ Pest control
○ Antibiotics
○ Understanding disease
○ Higher crop yields
○ Understanding our history from DNA
What is an example of a cetacean
○ Whales
○ Dolphins
What traits do cetaceans share with fish
○ Streamlined bodies
○ Marine living
○ Fins
What traits do cetaceans share with mammals
○ Lungs
○ Placenta
○ Milk production
○ Hair in developing embryo
○ Live birth
○ Three inner ear bones
Are whales fish or mammals
○ Mammals
○ Evolved from terrestrial mammal through natural selection
What is natural selection
○ A mechanism that can lead to evolution, whereby differences in survival and reproduction of individuals cause some genetic types to replace others
What does darwin's hypothesis predict regarding whales
○ There will be intermediate species in the fossil record showing the transition from terrestrial mammal to whales today
What is the Dorudon (Spear tooth)
○ 40mya
○ Many whale-like structure
○ Fully aquatic
○ HAS TEETH
What is the Ambulocetus (Walking Whale)
○ 48 mya
○ Short legs and mig feet
○ Walk on land and swim like otter
What is the pakicetus (Whale of Pakistan)
○ 50mya
○ Skull and inner ear structure similar to whale
○ Fully terrestrial
What does the fossil record show about this transition
○ Gradual
○ Reduction of pelvis and hind limbs
○ Nasal opening shifts to top
○ Eyes shift to side
What can the O18/O16 ratio reveal
○ Higher ratio = in bones of marine animals
○ Ratio increases in the transition to whales in fossil record
What group of land mammals is closest related to whales
○ Artiodactyls (hippos, cows, camels)
Which artiodactyl is closest to cetaceans
○ Hippos
What is the relationship between whales and hippos
○ They share a more recent common ancestor with each other than any species of land mammals
What is the genetic regulation of hindlimb development in cetaceans
○ Hind limbs start to grow in cetacean embryos
○ After a few weeks, they degenerate due to genetic mutations that turn off the development
What is a homology
○ Shared characteristics in a group of species because they were inherited from a common ancestor
○ Ex) Shared traits between whales and mammals
What is convergent evolution
○ Shared characteristics in a group of species that evolved independently due to natural selection to similar environments
○ Ex) Shared traits between whales and fish
What is a mutation
○ Any change to the genetic material of an organism
○ They can be harmful, beneficial, or neutral
How do most mutations impact an organisms ability to survive and reproduce
○ Neutral / mildly deleterious
What is an example of a beneficial viral mutation
○ Helps evade host immune system
○ Helps hijack host immune system
○ Makes it easier to survive and reproduce
What is zoonotic transmission
○ New mutations allow for viruses to jump between hosts
○ Ex) Covid 19 and Spanish Flu
How common is zoonotic transmission
○ Not very
○ Rare to be able to jump host
○ Rarer to survive and reproduce
What are some targets for vaccines
○ Areas on a viral gene code that have not encountered lots of mutations
What are some questions that evolutionary biology can answer with virology
○ How and where did SARS-COV-2 originate from
○ How long will vaccines provide protection
○ Public health policy
○ Preventing pandemics
What are the three key aspects of the hypothetico-deductive method
○ Falsifiable hypothesis
○ Generate predictions
○ Testing predictions with observable data where result is not yet known
What are the three possible outcomes of an experiment
○ Reject hypothesis
○ Modify hypothesis
○ Provisionally accept hypothesis
Can an experiment ever prove a hypothesis is correct
○ No
What is a hypothesis
○ An informed conjecture or statement about what might be true
What is a theory
○ A comprehensive, coherent body of interconnected statements, based on evidence and reasoning, that explain some aspect of nature
What is a fact
○ A hypothesis that has endured so much testing that we act as if it is true
Is evolution a hypothesis, theory, or fact
○ ALL THREE
What were darwin's two hypotheses in Origin of Species
1. Organisms descended with modification from a common ancestor
2. The main cause of this variation is natural selection acting on hereditary variation
What is the scientific theory of evolution
○ The explanation of how modification occurs and how ancestors give rise to diverse descendents
What was the early view on diversity
○ Non-existant
○ Theory of the forms
○ Species have fixed properties
What was the great chain of being
○ Not very details
○ Fixed hierarchy of species arranged from lower to higher forms
Who was carl linneus
○ Father of taxonomy
○ His system worked because classified taxa based on shared homologies between groups
○ 1700s
What is taxonomy
○ The science of describing, naming, and classifying species
What are the taxa
○ Groups of organisms in cohesive units
Who was nicholas steno
○ Recognized fossils were once living things
○ Shark teeth arent tounge stones
○ Pioneered stratigraphy
What is stratigraphy
○ The study of layering in rocks
Who was georges cuvier
○ Pioneered paleontology
○ Discovered many mastodons and mammals
○ Fossils resemble but arent the exact same as modern species
What is paleontology
○ The study of prehistoric life
Was the idea of extinction innitially accepted
○ No, it went against ideas of European naturalist, and were hard to incorporate
Who was mary anning
○ Found fossils of many marine vertebrates that were no longer living (extinct)
○ Pioneered the idea of extinction
Who was william smith
○ British canal surveyor
○ Different rock layers contain different fauna
○ Contributed the idea that the animal makeup of an area changes over time
Who was george buffon
○ Said life emerged as distinct types but changed with the environment
○ Said earth is older than people thought based on laws of physics and chemistry
Who was jean baptiste lamark
○ Said life is driven from simple to complex
○ Believed in inheritance of acquired changes
○ Complex life comes from microbes
Who was the first to propose a correct mechanism for how life changes over time
○ Charles darwin
What was important about the voyage of the HMS Beagle
○ 5 years
○ Charles darwin collected extensive evidence in support of natural selection
○ The birds weren't different species...all on the island he saw were finches
○ Darwin sat on his ideas for 20 years
Who was alfred russel wallace
○ Independently came up with many ideas on natural selection and common ancestry similar to charles darwin
What were the two key ideas in on the origin of species
○ All species share a common ancestor
○ Changes occur through natural selection
Who was Thomas Maltheus
○ Inspired Alfred russel wallace and charles darwin
○ Wrote that the population growth of the poor exceeded the supply of the nation's food
○ Idea of a fierce struggle for survival
What are the 5 facts of natural selection
1. High birth rates predict exponential growth
2. Population sizes are normally stable
3. Natural resources are limited
4. No two individuals are exactly the same
5. Variation is heritable
What are the 3 inferences from these facts
○ Since there are more individuals born than can survive, there is a fierce struggle for existence
○ Survival depends on heritable variation
○ Over generations, heritable variation that leads to increase in survival will increase in frequency
Who was Charles Lyell
○ Published principles of geology
○ Contained idea of uniformitarianism
What is uniformitarianism
○ Idea that Earth's landscapes have been shaped over time by the cumulative processes visible today
Charles Darwin and the Weald
○ Landscape
○ Charles darwin used rates of decay that the landscape formed over the course of 300 million years
○ Earth is very old
What did lord kelvin do
○ Studied heat loss of planet to predict earth was 20 million years old
○ Incorrect because erroneous prediction about content of Earth's core
When did indisputable evidence of Earth's age come to light
○ When understanding of atoms and radiometric dating of rocks came about
What is a half life
○ Time it takes for half the atoms in a given sample to decay
What is the significance of there not being short-lived isotopes in Earth's rocks
○ It means that Earth is very old, far older than most predicted
What is radiometric dating
○ Estimating the age of something based on isotope ratios
What is an isochron
○ Based on radiometric dating
○ Shows when something formed
○ All the rocks formed at the same time
How old is Earth
○ About 4.568 billion years
How old is the solar system
○ About 4.6 billion years
Why can't you use radiometric dating in fossils
○ They usually don't contain the isotopes
What do you do instead
○ Radiometric dating of the nearby rocks
What is radio carbon dating
○ Using the decay of C-14 to date organic material less than 50,000 years old
○ Half-life of 5730 years
Why is the fossil record incomplete
○ Organisms are eaten or destroyed before the slow process of fossilization can take place,
erosion from exposure to the elements
○ Even if it does fossilize, can be destroyed before observed
What else can fossils show
○ Mating behaviors
○ Nesting behaviors
○ Entire ecosystems
○ Reproductive strategies
○ Cellular structure (melanosomes)
How old is the galaxy
○ 10 billion years
How old is the universe
○ 14 billion years
What is life
○ An assemblage of molecules that can capture energy from the environment and replicate itself
What happened 4.5 bya
○ Earth cooled and formed a crust
○ Liquid oceans began to appear
What happened 4.4 bya
○ Large collision lead to formation of the moon
When happenedd 3.8 bya
○ Late heavy bombardment ended
What is an indication that all life today was descended from a common ancestor
○ Only L amino acids
What are zircons
○ Microscopic crystals
○ Potentially a biomarker
○ 4.1 bya
Why is early evidence of life controversial
○ Many of the "biomarkers" could potentially have been produced by a non-living source
What is the most widely accepted first evidence of liife
○ Stromatolites
○ 3.5 bya
What are stromatolites
○ Mineralizations of bacteria
What type of life was there for the first 2 billion years
○ Single celled
○ Eukaryotes, Bacteria, and Archaea all came about during this period
What are prokaryotes
○ Single-cellular organisms that lack membrane bound organelles and nucleus
○ Bacteria
○ Achaea
What are eukaryotes
○ Have membrane bound organelles
○ Arose from symbiosis between archaea and bacteria
What happened 2.4-2.7 bya
○ Cyanobacteria came about and started producing oxygen
What happened 2.3 bya
○ Great oxygenation event
○ Oxygen = toxic, kills most bacteria
○ Earth covered in rust
What is aerobic respiration
○ Requires oxygen to make ATP, providing cells with energy
○ More efficient than anaerobic
What happened 2.1 bya (and eukaryotes 1.6bya)
○ Multicellular life
What are the advanteges of multicellular life
○ Damage protection
○ Protection from predation
○ Division of labor between cell types
What happened 715 mya
○ Snowball earth hypothesis (likely from volcanic activity)
○ Lasted 100 million years
What happened after the snowball earth
○ Life got larger and more complex
What happened around 600-800 mya
○ First animals, resembled sponges
What are some features that define animals
○ Multicellular
○ No cell walls
○ Respond to their environment in complex ways
○ Complex nervous system
○ Get energy by eating things
What happened 585 mya
○ First evidence of animal locomotion, burrow