Pharm EXAM substance abuse

what federal law reduced the chance for drug diversion

controlled substance act

schedule 1 drug is

• no approve uses

• not prescribed

• EX: COCAINE

schedule drug 2 is

• special prescribing requirements

• adderal

schedule 3 and 4 drug

• majority controlled substances

• diazepines

schedule 5 drug

• very few

• non in the state of TX

what agency enforces CSA

DEA

how is alcohol acute overdose treated

• gastric lavage

• dialysis

which drug is used to facilitate alcohol withdrawal

• benzodiazepines

which drug is used to facilitate alcohol maintain abstinence

• naltexone

• acamprosate

alcohol acute

removed by lavalge and dialysis helping alcohol excretion

alcohol use disorder

SEVERE alcohol dependence symptoms that are concerning

how do you treat nicotine poisoning

• activated charcoal

• respiratory support

what drug is used to aid smoking cessation

• nicotine replacing therapy

• varenicline « most effective

• bupropion » weight loss

which drug is used to treat acute toxicity of major drug abuse

naloxone: narcan

which drug is used to treat detoxification of alcohol abuse

• methadone substitution

• buprenorphine

• clonidine assisted withdrawals

which drug is used to treat long term management for drug abuse

• methadone «« sever addiction»»pt has to go clinic to recieve treatment

• buprenorphine

• naltexone

if someone is present in the ER for overdose do you stop or continue administering nalaxone - for sure an exam ?

keep administering naloxone they are already overdosed so the goal is to do the opposite of that

most neuropharmacologic agents act by ___ to exert effect

altering synaptic transmission

PNS side effects in the body

• slows HR

• increase gastric secretion

• emptying bladder

• emptying bowel

• focusing the eye for near vision

• constricting the pupil

• contracting bronchial smooth muscle

SNS side effects in the body

• regulate cardiovascular system

• regulate body temp

• implements acute stress response (fligh-flight reactions)

what is bethanicol?? a cholinergic drug used for

urinary retention

what is atropine??? , a cholinergic drug used for":

• preanesthetic> to prevent bradycardia

• mydriasis surgery , eye exam , able to paralyse cilliary muscle

• dysentery and diverticulitis by decreasing tone and motily of smooth muscles in intestine

• reverse bethanicol and cholinesterase

which anticholinergic drug is used for overactive bladder

primary selectives : oxybutynin and solifenacin

what drug is used to treat myasthenia gravis in the hospital

neostigmine , bioxiverz

what drug is used to treat myasthenia gravis when patients are discharged from the hospital

pyridostigmine: mestinon

which drug is used for muscle relaxation during surgery , mech vent, endotracheal intubation

competitve agens such as

• atrascurium

• cisatracurium

• mivacurium

• pancuronium

depolarizing agents such as : succinylcholine , anectine

which neuromuscular blocker is primarily used for endotracheal intubation

depolarizing agent : succinylcholine: anectine

which adrenergic agonist is used for anaphylactic shock

epinephrine

alpha blocker for HTN and BPH

• tamsulosin

• alfuzosin

• silodosin

alpha blocker for only BPH

• tamsulosin

• alfuzosin

• silodosin

beta blocker is non selective and thus have may cardiovascular indication

propranolol- inderal LA

which beta blocker is primarily for HTN

2nd generation cardio selective

which beta blocker has vasodilating actions

• carvedilol

• labetalol

• nebivolol

whcih centrally acting A2 agonist can be used for HTN and DHD

clonidine

which centrally acting A2 agonist can be used to manage HTN during pregnancy

methyldopa

which physiologic barrier impedes entry of drugs into the brain

blood brain barrier

first line drug for PD

levodopa/ carbidopa

which PD drug is used as an adjunct to levodopa to decrease wearing off

entacapone

which PD drug is used as an adjunct to levodopa to decreae wearing off

entacapone

which Parkinsons drug is used for newly diagnosed patients and managing off times during levodopa therapy

MAOB- inhibitor

• rasagiline

• tolcapanoe

which drug is used for Alzeheime’s disease

cholinesterase inhibitors

• donepezil

• rivastigmine

• galantamine

which drug is used for Alzeheime’s disease neuropsychiatric symptoms

• riseperidone

• olanzapine

which MS drug is also approved for chrons disease

natalizumab

which drugs is used to treat fatigue in patient with MS.

• amantadine modafinil

• provigil

which drug is used to treat cognitive dysfunction in patient with MS.

• donepezeil

which drugs is used to treat ataxia and tremor in patient with MS.

• clonazepam

• primidone

• propranolol

which drug is used to improve walking in patient with MS.

dalfampridine

pt with seizures, what drug is appropiate for seizures

valproic acin , carbamazepine

which drug is used to treat muscle spasms and spasticity

• central acting muscle relaxants

• baclofen

• clarisoprodol

• chlorzoxazone

• cyclobenzaprine

• diazepam

• metaxalone

• methocarbamol

• orphenadrine

• tizanidine

• DIrect acting muscle relaxants

• dantrolene

which muscle has a sedating effect

diazepam

most abused muscle relaxant

clarisoprodol

alpha blocker used for diagnosis, prevention or reversal of BPH

phentolamine