Cholinergic Agonist And Antagonist

Direct Acting Cholinergic

Acetylcholine

Bethanechol

Pilocarpine

Acetylecholine

Used to produce miosis in ophthalmic surgery

-direct

Bethanechol

Used in treatment of urinary retention

-direct

Pilocarpine

Reduces intraocular pressure in open-angle and narrow-angle glaucoma

-direct

Indirect-Acting Cholinergic Agonist

Neostigmine

Edrophonium

Neostigmine

Used in the treatment of myasthenia gravis

-indirect

Edrophonium

Used for diagnosis of myasthenia gravis

-indirect

3 Types of Cholinergic Antagonists

Antimuscarinic Agents

Ganglionic Blocker

Neuromuscular blocker - non-depolarizing

Neuromuscular blocker - depolarizing

Name the 3 Antimuscarinic agents

Atropine

Scopolamine

Ipratropium

Name 1 ganglionic Blocker

Nicotine

Name two non-depolarizing neuromuscular blockers

Rocuronium

Cisatracurium

Name 1 depolarizing neuromuscular blocker

Succinylcholine

Atropine

Used for mydriatic and cycloplegic effects, Gi spasm, organophosphate poisoning

-antimuscurinic

Scopolamine

Used to prevent motion sickness

-antimuscurinic

Ipratropium

For COPD and Asthma

-antimuscurinic

Nicotine

Smoking cessation

-ganglionic blocker

Rocuronium

General anesthesia medicines for rapid sequence intuition and routine tracheal intubation

-neuromuscular nondepo

Cisatracurium

Muscle relaxant

-neuromuscular nondepo

Succinylcholine

Muscle relaxant; rapid endotracheal intubation

-neuromuscular depo