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metabolism
sum of all chemical reactions in the body
cellular metabolism
sum of all chemical reactions occurring in a cell
anabolism
small molecules are built into large ones; requires energy
catabolism
larger molecules are broken down into smaller ones; releases energy
dehydration synthesis
smaller molecules are bound together to for larger ones; h2O produced in the process; used to produce poly saccharides, proteins, and triglycerides; example of anabolism
hydrolysis
used to decompose carbohydrates, proteins, and lipids; uses h2O to split the substances; reverse dehydration synthesis; example of catabolism
enzymes
control rates of both catholic and anabolic reactions; greatly increase reaction rates
enzymes (protein catalysts)
Globular proteins that catalyze specific reactions
• Increase rates of chemical reactions
• Lower the activation energy necessary to start reactions
Not consumed in the reaction, so are used repeatedly
• Each enzyme is specific to a particular substrate
• Ability to recognize substrate depends on shape of active
site of enzyme
cofactor
non-protein substance that combines with the enzymes to activate it
some help fold active site into proper conformation
some help bind enzyme to substrate
can be ion, element, or small organic molecule
coenzyme
organic molecule that acts as cofactor
most are vitamins, which are essential organic molecules that humans must get from their diet
cellular respiration
process that transfers energy from molecules, and makes it available for cellular use
atp (adenosine triphosphate)
molecule that carries energy in a form the cell can use; main energy carrying molecule in a cell; energy from atp breakdown is used for cellular work
atp 3 portions
adenine, ribose, 3 phosphates
2nd and 3rd phosphate are attached by
high energy bonds
when atp loses last phosphate it becomes
adenosine dephosphate (adp)
when adp can be converted back into atp by attaching a 3rd phosphate
phosphorylation (requires energy from cellular respiration)
cellular respiration of glucose occurs in 3 interconnected
reaction sequences
glycolysis (anaerobic), citric acid cycle (aerobic), electron transport chain (aerobic)
occurs in a metabolic cycle in which the final product reacts to replenish original substrate
citric acid cycles
anaerobic reaction
do not require O2, makes little atp
aerobic reaction
requires O2; make most of ATP
glycolysis
break down of glucose into 2 smaller molecules; anaerobic, occurs in cytosol
glycogen
the stored form of glucose
glycogenolysis
glycogen is broken down into glucose to provide immediate energy
glycogenesis
the process of synthesizing glycogen from glucose