Solvents for Liquid Preparations

Alcohol USP

Most useful solvent in Pharmacy and is the primary solvent for organic compounds.

Solvent, Preservative

Alcohol USP is used as a ___ and a ____

0.5%

What is the recommended alcohol USP limit for OTC oral products for those under 6 years?

5%

What is the recommended alcohol USP limit for OTC oral products for those 6-12 years old?

10%

What is the recommended alcohol USP limit for OTC oral products for those over 12 years?

Diluted Alcohol NF

This solvent is prepared by mixing equal volumes of alcohol USP and purified water USP.

3%

Diluted Alcohol NF contracts upon mixing by how much in %?

49%

What is the approximate concentration (%) of diluted alcohol NF?

Diluted Alcohol NF

This solvent is a useful hydroalcoholic solvent in various processes and preparation.

Rubbing Alcohol

Which solvent contains 70% ethyl alcohol by volume; volatile and flammable

Sucrose Octaacetate, Denatonium Benzoate

In each 100mL of Rubbing alcohol it must contain: ____ and ______, which provides a bitter taste that discourages accidental/abusive oral ingestion

355 mg

In 100mL of rubbing alcohol, how much Sucrose octaacetate is present?

1.4mg

In 100mL of rubbing alcohol, how much Denatonium benzoate is present?

Rubefacient, germicide, vehicle

Rubbing alcohol is usually employed/used in topical preparations as the ff.

Isopropyl Rubbing Alcohol

Which solvent contains 70% isopropyl alcohol by volume?

Rubefacient, soothing rub, vehicle

Isopropyl Rubbing alcohol is employed/used in topical preparations as the ff.

Glycerin USP

This solvent is a clear syrupy liquid with a sweet taste; miscible in both water and alcohol.

stabilizer, auxiliary solvent

Glycerin USP possesses a preservative quality and is used as a ____ and ____

Propylene Glycol USP

This solvent is a viscous liquid; miscible in water and alcohol; and frequently substituted for Glycerin in modern pharmaceutical formulations

Purified Water USP

This solvent has fever solid impurities than ordinary drinking water and is intended for use in preparation of aqueous dosage forms (Not intended for parenteral administration)

Distillation method, Ion exchange method, Reverse osmosis

Purified Water USP is prepared by the ff. methods: