Monitoring Parameters

Acetylcysteine (Mucomyst, Mucosil, Acetadote)

Blood glucose, LFTs, PT, SCr, BUN, serum electrolytes

Acyclovir (Zovirax)

Cr, BUN

Adenosine (Adenocard, Adenoscan)

ECG, HR, BP

Alteplase, Recombinant (Activase)

CPK, ECG, Hgb, Hct, PT, PTT, Thrombin Time

Amikacin Sulfate (Amikin (Apothecon))

Urinalysis, BUN, Cr, peak and trough cone, vital signs, temp, weight, I&O, hearing fx

Amiodarone (Cordarone)

CBC, Chest C Ray, ECG, LFTs, eye exam, PFTs, thyroid fx

Amphotericin B (Fungizone, Amphocin)

CBC, Cr, BUN, Mg, K, Na

Ampicillin Sodium (Principen)

BUN, SCr

Ampicillin Sod & Sulbactam Sod (Unasyn)

None

Atropine (AtroPen, Isopto Atropine, Sal-atropine)

HR, BP, pulse, mental status, IV admin requires cardiac monitor

Azithromycin (Zithromax)

LFTs

Aztreonam (Azactam)

LFTs, BUN, Cr

Bumetanide (Bumex)

BP, electrolytes, BUN, Cr

Buprenorphine Hydrochloride (Buprenex)

Pain relief, BP, LFTs, CNS Depression

Butorphanol Tartrate (Stadol)

Pain relief, respiratory and mental status, and BP

Caspofungin (Cancidas)

CBC, LFTs, serum potassium

Cefazolin Sodium (Ancef)

Renal function, CBC, LFTs, signs/sx of anaphylaxis

Cefepime (Maxipime)

signs/sx of anaphylaxis, culture and sensitivity of specimen

Cefotaxime Sodium (Claforan)

Renal and hepatic function with prolonged use, signs of anaphylaxis

Ceftriaxone Sodium (Rocephin)

signs/sx of anaphylaxis

Cefuroxime Sodium (Ceftin, Zinacef)

with prolonged therapy, monitor renal, hepatic, and hemotologic fx periodically

Chlorpromazine Hydrochloride (Thorazine)

Vital signs, lipid profile, FBG, HbA1c, BMI, mental status, EPS

Cidofovir (Vistide)

Cr, BUN, UAs within 48h of each dose, LFTs, WBCs, IOP, signs/sx of uveitis/iritis

Ciprofloxacin (Cipro IV (Bayer))

Serum levels of theophylline or cyclosporine if receiving concurrently, CBC, renal and hepatic fx with prolonged therapy

Cisplatin (Platinol)

BUN, Cr, CrCl, electrolytes before and within 48h after dose, audiography, neurologic exam, LFTs periodically, CBC with diff, urine output

Clindamycin Phosphate (Cleocin)

Monitor for colitis, CBC (with prolonged therapy), LFTs and RFTs (periodically)

Dantrolene (Dantrium)

Performance, N/V, LFTs, cardiac monitoring and BP

Daptomycin (Cubicin)

RFTs, CPK (weekly or more frequently if on statin therapy), muscle pain or weakness, especially in distal extremities

Darbepoetin Alfa (Aranesp)

Hgb, iron, BP

Dexamethasone Sodium Phosphate (Decadron, Hexadrol, Dalalone)

Hgb, occult blood loss, K and glucose, IOP if use >6w

Diazepam (Valium)

Respiratory, CV, and mental status. Check for orthostasis

Digoxin (Lanoxin)

Drug serum [ ], HR and rhythm, K, Mg, Ca, RFTs, noncardiac signs of toxicity

Diltiazem (Cardizem)

LFTs, BP, ECG

Diphenhydramine Hydrochloride (Benadryl)

Relief of sx, mental status

Dobutamine (Dobutrex)

BP, ECG, HR, CVP, RAP, MAP, urine output, K

Dolasetron (Anzemet)

LFTs, BP and pulse, ECG in pts with CV disease

Dopamine Hydrochloride (Intropin)

Behavior, mood, bowel fx, cognitive fx, general fx

Doripenem (Doribax)

Cr, BUN

Doxycycline Hyclate (Vibramycin)

LFTs

Droperidol (Inapsine)

None

Drotrecogin Alfa (Xigris)

Bleeding, D-dimer

Enalaprilat (Vasotec)

BP, RFTs, WBC, K

Enoxaparin Sodium (Lovenox)

Platelets, occult blood, antiXa activity, PT (if applicable)

Epinephrine Hydrochloride (Adrenalin, Epipen)

PFTs, HR, ECG, BP

Epoetin Alfa (Epogen, Procrit)

BP, Hct, Hgb, CBC with diff, transferring saturation and ferritin

Ertapenem (Invanz)

Periodic RFTs, LFTs, and hematopoietic assessment; neurological assessment

Erythromycin Lactobionate (Erythrocin)

LFTs, ECG

Esomeprazole (Nexium)

LFTs

Famotidine (Pepcid)

Intragastric pH, serum Cr, BUN

Fentanyl (Sublimaze)

Respiratory and cardiovascular status, BP, HR, signs of misuse, abuse, or addiction

Filgrastim (Neupogen)

CBC with diff, monitor for neutropenia

Fluconazole (Diflucan)

Periodic LFTs, RFTs, serum K

Foscarnet (Fascavir)

CrCl, CBC, electrolytes, hydration status

Fosphenytoin Sodium (Cerebyx)

Continuous BP, ECG, respiratory fx, VS, CBC, LFTs, drug plasma levels

Furosemide (Lasix)

Weight, I&O, BP, orthostasis, serum electrolytes, RFTs, hearing function at high doses

Ganciclovir Sodium (Cytovene)

CBC with diff, SCr, ophthalmologic exams

Gatifloxacin (Tequin)

WBC, s/s infection, s/s hypo/hyerglycemia

Gentamicin (Garamycin)

Urinalysis, urine output, BUN, Cr, hearing test before and after tx

Granisetron (Kytril)

Chest pain, respiratory difficulty, pain or itching, as well as s/s of N/V

Haloperidol (Haldol)

VS, lipid profile, FBG, HbA1c, BMI, mental status, EPS

Heparin Sodium

platelet counts, Hgb, Hct, signs of bleeding aPTT

Hydralazine HCl

BP, HR, ANA titer

Hydrocortisone Sodium Succinate (A-Hydrocort, Solu-Cortef)

Bp, weight, serum glucose, electrolytes

Hydromorphone HCl (Dilaudid)

Pain relief, respiratory and mental status, BP

Imipenem-Cilastin (Primaxin)

Periodic RFTs, LFTs, and hematologic fx tests, s/s anapylaxis

Infliximab (Remicade)

VS< LFTs, s/s infection, annual PPD

Iron (Infed, Venofer)

Ferritin, Hgb, Hct, serum iron, transferrin

Ketorolac Tromethamine (Toradol)

Pain response, weight gain, edema, RFTs, observe for bleeding, bruising, evaluate GI effects, mental confusion, CBC, LFTs

Labetalol HCl (Normodyne, Trandate)

BP, HR, cardiac monitor

Leucovorin Calcium (Wellcovorin)

Drug concentrations

Levofloxacin (Levaquin)

RFTs, LFTs, ophthalmologic fx, hematopoietic fx, WBC, s/s infection

Levothyroxine (Levoxyl, Synthroid)

Thyroid fx test, HR, BP, s/s hypo- or hyperthyroidism

Lidocaine HCl (Xylocaine)

ECG

Linezolid (Zyvox)

CBC, visual fx

Lorazepam (Ativan)

Respiratory and cardiovascular status, BP, HR, s/s anxiety

Mannitol (Osmitrol)

Fluid balance, electrolytes, and renal fx

Meperidine HCl (Demerol)

SCr, BUN

Meropenem (Merrem)

s/s anaphylaxis

Methotrexate (Rheumatrex, Trexall)

CBC, LFTs, SCr/BUN, serum uric acid

Methylprednisolone Sodium Succinate (Solu-Medrol, A-Methapred)

BP, BG, electrolytes

Metoclopramide (Reglan)

dystonic reactions, s/s hypoglycemia, agitation and confusion

Metoprolol (Lopressor)

Serum electrolytes, RFTs, BP

Metronidazole (Flagyl)

None

Micafungin (Mycamine)

BMP, LFTs

Midazolam HCl (Versed)

Respiratory and CV status and BP

Milrinone Lactate (Primacor)

Cardiac monitor and BP, serum K

Morphine Sulfate (Duramorph, Astramorph/PF)

pain relief, respiratory and mental status, BP

Nafcillin Sodium

CBC, urinalysis, BUN, SCr, AST/ALT, s/s anaphylaxis

Nalbuphine HCl (Nubain)

pain relief, respiratory and mental status, BP

Naloxone (Narcan)

Respiratory rate, HR, BP

Nitroglycerin (Tridil, Nitro-Bid)

BP and HR

Norepinephrine (Levophed)

VS, s/s ototoxicity

Olanzapine (Zyprexa)

VS, BG, BP, EPS, mental status, and abnormal involuntary movement scale

Ondansetron HCl (Zofran)

LFTs

Oxytocin: (Pitocin)

Fluid intake and output during admin; fetal monitoring

Palonsetron HCl (Aloxi)

K, Mg, BG, Ca, EKG

Pamidronate Disodium (Aredia)

Serum Ca, electrolytes, phosphate, Mg, CBC

Pantoprazole Sodium (Protonix)

Acid output measures (target level <10mEq/hr)

Penicillin G (Pfizerpen)

None

Pentobarbital Sodium (Nembutal)

respiratory status, cardiovascular status, CNS status, cardiac and BP monitor may be required