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The breakdown of glucose into two molecules of pyruvate (C3H4O3), occurring in the cytoplasm, producing 2 ATP and 2 NADH without oxygen.
ATP is produced by the ATP synthase enzyme using energy from the proton gradient by adding a phosphate group to ADP
A process that occurs when oxygen is unavailable, converting pyruvate to lactic acid and regenerating NAD+ to continue glycolysis
Since NADH is needed for glycolysis, accumulation of lactic acid can be detrimental to cells in the long term.
Pyruvate Oxidation (Before krebs cycle)
One carbon is removed from pyruvate to form CO2
What happens to the remaining molecule in pyruvate oxidation?
Remaining molecule is oxidized, transferring electrons to NAD+ which is reduced to NADH
what coenzyme does the molecule attach to in pyruvate oxidation?
The remaining molecule attaches to Coenzyme A, forming Acetyl-Co (C21H36N7O16P3S).