What type of tissue is blood?
Connective tissue
What are the three functions of blood?
Transportation, defense, and maintenance of homeostasis.
What are the three layers of blood?
Plasma, buffy coat, and RBC layer
what are red blood cells called?
Erythrocytes
What is the name for white blood cells?
Leukocytes
What does hematocrit measure?
Measures the percent of RBC’s
What is the structure of a RBC
small
a biconcave disc- plump outside, thin middle
Why is the size and shape of RBC’s important?
High SA to Volume ratio- important for gas exchange
Discs can stack - can go through narrow vessels
discs can bend and flex entering small capillaries
What are the five types of white blood cells?
Neutrophils
Lymphocytes
Monocytes
Eosinophils
Basophils
What ones are granulocytes vs agranulocytes?
Granulocytes- the phils
agranulocytes- the cytes
Neutrophils
most abundant
multilobed nuclei
phagocytize pathogens and debris
Pale red and blue cytoplasmic granules
Eosinophils
bilobed nucleus
Red cytoplasmic granules
kill parasitic worms
role in allergies and asthma
Basophils
least abundant
lobed nucleus
large blue/purple cytoplasmic granules
release histamine and contain heparin
Monocytes
U/kidney shaped nucleus
Gray/blue cytoplasm
largest WBC
develop into macrophages and phagocytize debris and pathogens
lymphocytes
Spherical/indented nucleus
Pale blue cytoplasm
most immune response, direct cell attack
Platelets
Cytoplasmic fragments containing granules
stain in deep purple
seal small tears in blood vessels, instrumental in clotting
What are the 4 basic blood types (no positives or negatives)
A, B, AB, and O
Is Rh pooling an indication of + or - blood?
+ blood type
What blood types can receive what blood?
A- receive A and O (can donate to A and AB)
B- receive B and O (Can donate to B and AB)
AB- receive all blood (can donate only to AB)
O- only O (Can donate to all blood types)
Pericardium
around the heart
contains 2 layers, fibrous and serous pericardium
Parietal vs. Visceral pericardium
parietal -outer wall
visceral -inner wall
Blood flow through the heart
Right atrium → tricuspid valve → right ventricle → pulmonary semilunar valve → pulmonary trunk → pulmonary arteries → lungs > pulmonary veins > left atrium > mitral valve > left ventricle > aortic semilunar valve > aorta
what are the three blood flow circuits?
Coronary
Pulmonary
Systemic
Order of cardiac action potential
SA Node
AV node
AV Bundle (Bundle of His)
Bundle branches
Purkinje fibers
SA Node
initiates atrial depolarization
AV Node
conduction system is delayed
P wave (what happens)
Atrial depolarization (deflection from atrial depolarization)
QRS complex
Atrial repolarization, ventricular depolarization
T wave
Ventricular repolarization
ECG/EKG what does it stand for?
What does one waveform show?
Electrocardiogram
One waveform= one heart beat
Baroreceptors
respond to changes in blood pressure
Chemoreceptors
respond to concentration of chemicals
What leads to cardioinhibitory center stimulation?
BP increase
Increase in O2, pH
Decrease in CO2
Stroke volume
The amount of blood pumped out by one ventricle during one heart beat
Cardiac output
Heart rate x Stroke volume
amount of blood pumped out in one minute
Systole
Contraction
Diastole
Relaxation
EDV
End diastolic volume
amount of blood that collects in ventricle during diastole
ESV
End systolic volume
amount of blood remaining in the ventricles after contraction
Pulse Pressure
Systolic - Diastolic blood pressure
When are AV valves open? When are they closed?
Open- during filling and atrial contraction
Closed- Isovolumetric contraction, Ejection, and Relaxation
SL valves, when are they open? When are they closed?
Open- ventricular ejection
Closed- during filling, atrial contraction, isovolumetric relaxation and contraction.
Lub sound, what causes it?
Closing of the AV valves
Dup sound, what causes it?
Closing of the SL valves
How is blood pressure measured?
Systolic/Diastolic
5 auscultation sites?
Aortic area
Pulmonic area
Erb’s point
Tricuspid area
Mitral/apex area
what is used to measure blood pressure manually?
Sphygmomanometer and stethoscope
Where are the 7 points you can take a pulse?
temporal
carotid
brachial
radial
femoral
Dorsalis pedis
Posterior tibial