what is the site of the tubular reabsorption and tubular secretion?
renal tubule
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where do the distal convoluted tubules empty into?
the collecting duct
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what renal structure receives urine from nephrons and delivers it to the calyces and renal pelvis?
collecting duct
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what are the two types of nephrons?
cortical and juxtamedullary nephrons
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what type of nephrons are located entirely in the cortex and make up the majority of nephrons?
cortical nephrons
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what type of nephron is found at the boundary of the cortex and medulla and plays an important role in concentrating urine?
juxtamedullary nephron
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what are the four basic renal processes?
filtration, reabsorption, secretion, and excretion
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which renal process moves from the glomerulus to the glomerular capsule?
filtration
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which renal process moves from the renal tubule to the peritubular capillaries?
reabsorption
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which renal process moves from the peritubular capillaries to the renal tubule?
secretion
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which renal process moves from the renal tubules to outside of the body?
excretion
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how is urine formed? (gf tr ts)
through glomerular filtration, and tubular reabsorption, then tubular secretion
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what substance contains everything that blood plasma does?
filtrate
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what substance is what remains after filtrate has lost most of its water, nutrients, and necessary ions?
urine
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what substances that aren’t needed does urine contain (name 2)
nitrogenous wastes and drugs
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why is urine yellow?
urochrome pigment
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what is the normal pH of urine?
6
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what is the normal range of specific gravity in urine?
1\.001 to 1.030
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what are some substances normally found in urine (name 3)?
sodium, potassium, urea, creatinine, ammonia, bicarbonate ions, etc.
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what solutes are NOT normally found in urine (name 3)?
glucose, blood, rbcs, hemoglobin, wbcs, bile, etc.
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high blood sugar levels; diabetes mellitus
glycosuria
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increased protein levels; hypertension or pregnancy
proteinuria
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excessive production of ketones; diabetes mellitus
ketonuria
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irritation of urinary tract and blood in urine; kidney stones or UTI
hematuria
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excess hemoglobin in urine; hemolytic anemia
hemoglobinuria
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excess nitrates in urine; UTIs
nitrituria
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excess bilrubin in the urine; liver damage or hepatitis
bilrubinuria
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pus in the urine; UTI or gonorrhea. WBCs
pyruria
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functional kidney
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functional kidney (section)
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kidney carcinoma
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mammalian ureter
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female mammalian urethra
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collapsed bladdder
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distended bladder
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Glomerular Filtration is Selective?
A non-selective process in Urine Formation that separates based purely on size.
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Glomerular Filtration
Water and solutes smaller than Proteins or Blood cells are forced through capillary walls into the renal tubule. One second its blood then it goes under high pressure and then its filtrate.
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Tubular Reabsorption
Water, Glucose, amino acids, and needed ions are transported out of the filtrate and into the tubular cells to then enter the capillary blood
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Tubular Secretion
Hydrogen ions, potassium ions, creatine, and some drugs are removed from peritubular blood and secreted by tubule cells into the filtrate.
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Tubular reabsorption happens before Tubular Secretion?
No, they happen at the same time
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Reabsorption is equally passive and active?
No, Reabsorption is mostly active and has some passive.
* NaCl * glucose * amino acids * bicarbonate (only in the distal tubule)
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Solutes reabsorbed by passive transport (out)
* Bicarbonate (only in proximal tubule) * Water * NaCl (ascending limb) * Urea (collecting duct)
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Glomerular Filtration rate
uses inulin to measure the rate at which the glomerulus filters solute from the plasma as inulin can only be filtered and not secreted or reabsorbed. Can detect kidney disease.