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the liver is a(n) ___ organ.
intraperitoneal
the covering of the liver is known as ____.
Glisson Capsule
what makes up the portal triad?
portal vein, hepatic artery, CBD
the caudate lobe is separated from the left lobe by the ____.
ligamentum venosum
the caudate lobe is bordered posteriorly by the ___.
IVC
in utero, the ____ becomes the ligamentum venosum.
ductus venosus
ligamentum teres is also known as the ___.
round ligament
in utero, the ligamentum teres is the ____.
umbilical vein
what percent of blood supply to the liver is from the MPV?
70%
what supplies the liver with oxygenated blood?
MPV and proper hepatic artery
the proper hepatic artery and the MPV enter the liver at the ____.
porta hepatis
MPV and the proper hepatic artery should have what type of flow?
hepatopetal
the hepatic artery has ___ resistance.
low
drainage of deoxygenated blood from the liver is by the ____.
hepatic veins
the hepatic veins show what type of flow?
hepatofugal
the portal vein shows what type of waveform?
steady, minimally phasic
the hepatic veins drain into the ____.
IVC and then into the right atrium
extension of the right lobe of the liver over the right kidney
Reidel’s lobe
to distinguish Riedel’s lobe from hepatomegaly, what should be looked at?
the left lobe for enlargement
inferior extension of the caudate lobe
papillary process
the liver is considered normal up to ____.
15 cm
the liver appears slightly ___ when compared to the right kidney.
echogenic
the MPV diameter should be ___.
1.3 cm
liver enzymes that are checked are ____, ____, and ___.
ALT, ALP, AST
ALT =
alanine transaminase
ALP =
alkaline phosphatase
AST =
aspartate transaminase
term used when bilirubin is elevated
hyperbilirubinemia
hyperbilirubinemia (elevated bilirubin) =
jaundice
another term for fatty liver disease is ___.
hepatic steatosis
fatty liver disease may lead chronic steatohepatitis which may lead to chronic disease such as ___.
cirrhosis
what is the most common diffuse liver disease and is most likely the reason for elevated LFTs?
fatty liver infiltration (hepatic steatosis)
clinical signs of fatty liver infiltration
elevated LFTs, no symptoms
sonographic appearance of fatty liver infiltration
echogenic/dense, poor through transmission (high attenuation), poor visualization of vascular
focal hypoechoic area, patch of normal liver, no mass effect
focal fatty sparing
what is the most common location of focal fatty sparing?
next to GB/porta hepatis
what is the most common cause of cirrhosis?
alcoholism
cirrhosis is the result of ____.
liver cell death and fibrosis/liver failure
clinical signs of cirrhosis
elevated LFTs, jaundice, fatigue, weight loss, diarrhea
sonographic appearance of cirrhosis
heterogeneous/coarse texture, small right lobe and enlarged caudate lobe, nodular surface, ascites
the nodular surface of a cirrhotic liver is best evaluated with ____.
higher frequency linear array
smaller nodules seen in cirrhosis patients when caused by alcoholism
micronodular
macronodular surface seen in cirrhosis are nodules measuring ____ when caused by ____.
>1 cm; hepatitis
patients with cirrhosis have an increased risk of ____.
portal hypertension and HCC
what is the most common cause of portal hypertension?
cirrhosis
increased pressure on the portal system, redirecting blood flow AWAY from the liver
portal hypertension
what occurs when pressure of liver disease increases too much?
resists flow coming into the liver and flow is drawn to other lower pressure channels; blood backs up into veins that normally drain into the PV causing dilation or venous collaterals
veins that normally drain into the portal vein =
splenic vein and coronary vein (left gastric)
sonographic appearance of portal HTN
hepatofugal flow, MPV measuring greater than 1.3 cm, dilated venous collaterals,
treatment for portal hypertension
TIPPS (transjugular intrahepatic portosystemic shunt)
communication or bridge between PV and HV to decompress the portal vein and normalize flow direction
TIPSS
if a TIPSS is successful, what will flow demonstrate?
hepatopetal at proximal RPV and hepatofugal at distal RHV
what is obstruction of the PV most commonly caused by?
tumors or lymphadenopathy
thrombosis of the PV may be caused by…
increased liver resistance (HCC, mets, portal HTN) or increased clotting factors
clinical signs of portal vein compression/thrombosis
elevated LFTs, hypovolemia, nausea, vomiting
sonographic appearance of portal vein compression/thrombosis
thrombosis of PV, cavernous transformation
portal vein compression/thrombosis could lead to cavernous transformation which = ____.
periportal collaterals
small vessels surrounding the portal vein to reroute the blood around the clot towards the liver
periportal collaterals
cavernous transformation is different that portosytstemic collaterals. portal HTN collaterals reroute the blood ____.
away from the liver
cavernous transformation is different that portosytstemic collaterals. cavernous transformation is rerouting the blood _____.
back into the liver
occlusion of the hepatic veins and possibly the IVC that leads to liver congestion and eventual liver necrosis
Budd-Chiari syndrome
in cases of Budd-Chiari syndrome, the ____ enlarges to compensate.
caudate
sonographic appearance of Budd-Chiari syndrome
hepatomegaly, enlarged caudate lobe, absent flow hepatic veins
hepatitis is a ____ infection.
diffuse
because hepatitis is a diffuse infection, LFT’s will always be ____.
abnormal
because abscesses are focal, LFT’s might be ___.
normal
fever + a focal finding likely = ____.
abscess
diffuse labs + fever = ___
whole organ infection
the most common form of hepatitis are ___ and ___.
A and B
hepatitis C is most likely the cause of needing ____.
liver transplantation
most common acute hepatitis
hepatitis A
hepatitis A has ____ route.
fecal-oral
clinical signs of acute hepatitis
fever, non-obstructive jaundice (elevated direct bilirubin), elevated LFTs
when acute hepatitis has progressed enough, what is the sonographic appearance?
starry sky, hepatomegaly, hypoechoic
most common chronic hepatitis
hepatitis C
hepatitis C is transmitted by ___.
bodily fluids
chronic hepatitis may have signs of ____ on ultrasound.
fibrosis or cirrhosis
clinical signs of liver abscesses
infection symptoms, fever, pain, leukocytosis
water-lily sign that is associated with daughter cysts
echinococcal cyst
an amebic liver cyst is from a parasite from ___.
water
amebic parasite affects ___ first.
GI
a pyogenic abscess is the result of…
another infection
cysts of the liver are mostly benign and asymptomatic and are associated with…
polycystic kidney disease
most common benign liver tumor
hemangioma
tumor of the liver that has a varied appearance, may be echogenic; associated with orgal contraceptives
adenoma
tumor of the liver made of fat that appears hyperechoic
lipoma
2nd most common benign liver tumor; may be isoechoic to the liver, central scar with vascularity
focal nodular hyperplasia (FNH)
a “bleed” from trauma or surgery
hematoma
hematoma occur within the organ/liver; more focal appearing
intraparenchymal hematoma
hematoma around the liver, just under the Glisson capsule; like free fluid
subcapsular
clinical signs of hematoma
trauma or biopsy history; decreased hematocrit, pain
sonographic appearance of hematoma
anechoic to echogenic depending on the age
hepatocellular carcinoma is also called ____.
hepatoma
increased risk for HCC is seen in patients with…
chronic liver disease, cirrhosis, hepatitis
most common primary liver cancer
HCC
tumor marker for HCC =
elevated AFP
usual sonographic appearance of HCC
usually solitary, hypoechoic mass, ascites
what are the most common sources of cancer found in the liver?
lung, colon, and breast
the liver is the most common location for ___.
mets