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4 types of macromolecules
carbohydrates, lipids, proteins, nucleic acids
dehydration synthesis
water removed to join 2 submolecules
hydrolysis
macromolecules broken down by adding water
monosaccharides
single sugars (glucose)
disaccharide
2 sugars/monosaccharides (sucrose)
polysaccharides
union of many monosaccharides (ex. starch)
proteins functions
building, repair and maintenance of cell structure
enzymes
proteins that speed up chemical reactions
what are proteins made from
amino acids together, peptide bond (polypeptides)
essential amino acids
obtained through diet, 9
what are fats made of
glycerol and fatty acids
triglycerides
glycerol and 3 fatty acids
animal triglycerides
saturated fats, solid
plant triglycerides
unsaturated oils, liquid
phospholipids
have a phosphate molecule attached to the glycerol backbone of the molecule, replaces one fatty acid, makes one end of the lipid polar
where are phospholipids found
cell membrane
catalysts
chemicals that control the speed of chemical reactions without altering the products formed by the reaction
enzyme
protein catalysts that regulate reactions within living organisms.
enzymes suffix
-ase
substrate
the molecule on which the enzyme works.
active site
area of the enzyme that joins with the substrate molecule. active site is a special shape that only certain substrates can fit into.
cofactors
inorganic molecules such as iron, zinc, and potassium as well as copper-containing compounds
coenzymes
organic molecules synthesized from vitamins
competitive inhibitors
molecules that have similar shapes to substrates. They compete with the substrate to bind at the active site.
non competitive inhibitor
attaches elsewhere on the enzyme, changes the 3-D shape of the enzyme, so the substrate cannot bind to the enzyme's active site
negative feedback loop
final product of a reaction tells the enzyme to ease off and slow down the process
feedback inhibition
the inhibition of an enzyme in a metabolic pathway by the final product of that pathway (it turns the enzyme off!)
precursor activity
the activation of the last enzyme in a metabolic pathway by the initial reactant (it turns the enzyme on!)
metabolism
refers to chemical reactions that take place within cells
chemical digestion
uses enzymes
peristalsis
involuntary constriction of tubular muscle to move food along tube
amalyse
enzyme in saliva, starch
gastric juices
acid and enzymes
cardiac sphincter (lower esophageal sphincter)
controls entrance into the stomach
chyme
soupy mixture created when stomach acid mixes food
pyloric sphincter
controls exit to small intestine
pepsinogen
secreted by chief cells, activated into pepsin, digests proteins
where is bile produced
liver
gastrin
hormone created in stomach, stimulates increased release of gastric juices
where is bile stored
gallbladder
what do bile salts do
emulsify fats, mechanical digestion
pancreas secretes
neutralizing chemical (sodium bicarbonate
digestive chemical
hormones
insulin
produced in pancreatic cells, increase the removal of glucose from blood
glycogen
stimulates the release of glucose into the blood stream
three sections of small intestine
duodenum, jejunum, ileum
villi and microvilli
bumps on small intestine increase SA
large intestine
stores and eliminates solid waste
3 parts of Loop of henle
ascending, transverse, descending
anal sphincter
controls the release of feces out of the body (voluntarily controlled)
what kind of digestion is bile
physical
kidneys function
filter blood waste and produce urine
ureters function
transport urine from the kidneys to the bladder
urinary bladder
stores urine until expelled from from body
urethra
conduit for urine to leave the body
how is skin excretory
excretes waste through sweat
how are lungs excretory
remove CO2 which is a waste product of cellular respiration
which diabetes means no ADH is produced
diabetes insipidus
how are intestines excretory
eliminate undigested food, waste product and toxins
pituitary gland
regulates water balance by releasing ADH influencing water reabsorption
glomerulus
filters blood in the kidneys, waste products to be removed from blood and excreted as urine
bowmans capsule
surrounds glomerulus, collects what has been filtered out
proximal and distal tubule
reabsorbs and secretes
loop of henle
creates concentration gradient allowing for reabsorption
renal medulla
the innermost part of the kidney
renal artery
carry blood from heart to veins
renal vein
blood vessel that carries blood away from the kidney and toward the heart
renal cortex
outer layer of the kidney
renal pelvis
central collecting region in the kidney
collecting duct
adjust final composition of urine before it is excreted
afferent arterioles
brings blood to the glomerulus
efferent arterioles
carries filtered blood away
peritubular capillaries
surround tubules of nephron in kidney - reabsorb water
filtration
from blood/glomerulus to nephron (pwrd by blood pressure)
reabsorption
from nephron to blood (diffusion + AT)
secretion
from blood to nephron (AT)
aldosterone
hormone that stimulates the kidney to retain sodium ions and water
diabetes mellitus
blood sugar levels continuously high, (glucose in urine)
diabetes insipidus
inadequate production of ADH, excessive urination and thirst (too clear)
nephritis
inflammation of kidney tissue (protein)
liver
break down metabolic wastes
where does ADH act
distal tubule + collecting duct
where does aldosterone act
distal tubule + collecting duct
proximal tubule function
reabsorption of glucose and amino acids
distal tubule function
secrete potassium and hydrogen ions
loop of henle function
reabsorb water and sodium
where does filtration occur
glomerulus
where does reabsorption occur
proximal + distal tubule, loop, collecting duct
where does secretion occur
distal tubule
aquaporins
increase permeability of nephron walls for water