The Race for the Double Helix

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31 Terms

1

Who was James D. Watson?

he was a molecular biologist, geneticist, and zoologist responsible for the first complete model of DNA with Francis Crick

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2

Who was Francis Crick?

he was a molecular biologist, biophysicist, and neurologist partly responsible for the first complete model of DNA with James D. Watson

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3

What was the year and location of James D. Watson’s international science meeting?

The year was 1951 and the locations was Naples, Italy

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4

What scientist did Watson desperately want to meet at his international science meeting?

Maurice Walkins

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5

What does Watson mean when he says that he is one of the believers?

He believes DNA holds the genetic secret

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6

In what city and country was Rosalind Franklin working before she went to King’s College London?

Paris, France

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7

What was physicist J.T. Randall’s position at King’s College?

His position was head of physics.

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8

Who was the director of the Cambridge Cavendish Laboratory?

Lawrence Bragg, son of William Bragg who, along with his father, won a Nobel prize in 1915.

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9

Who was the bright hope of the Cavendish Laboratory?

The bright hope was Francis Crick

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10

Who was Raymond Gosling?

He was a research student working with Maurice Wilkens

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11

Where did Rosalind Franklin’s DNA sample come from?

Rudolf Signer

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12

What does J.T. Randall say to Wilkens about formal structures and hierarchies in the labs at King’s College?

He claimed he didn’t like them and he preferred more flexibility

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13

How long was Rosalind Franklin working in Paris in a post-doctoral capacity?

She was there for four years

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14

“Science is a ____ activity.”

communal

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15

What piece of data did Watson forget when he heard Franklin speak about her work at King’s?

Watson thought Franklin meant 8 molecules of water per unit cell; what she said was 8 molecules of water per nucleotide.

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16

What is the asymmetric unit?

the smallest part of a crystal required to tell one the properties of a crystal’s structure

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17

What was the problem with Watson and Crick’s first DNA model?

They were missing the correct arrangement of bases and the correct amount of water

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18

At what famous university in the U.S. was Linus Pauling working as a Professor of Chemistry?

The university was Caltech

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19

Why couldn’t Linus Pauling come to Britain for a science conference?

He was invited to the royal society meeting.

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20

As what character did Jim Watson come to the costume party?

He dressed as a Vicar

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21

Who was J.T. Randall?

He was a physicist and a biochemist who improved the cavity magnetron.

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22

What did Erwin Chargaff contribute to the solution of the DNA structure?

He discovered the ratio of the DNA base pairs

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23

What are the DNA base pairings?

A-T, G-C

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24

Who was coming to work in the Cavendish who knew Linus Pauling very well?

Peter Pauling

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25

Rosalind Franklin was going to leave King’s College to go to what other college in London?

Birkback College

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26

How many chains did Linus Pauling’s erroneous DNA structure have?

3 chains

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27

What did Maurice Wilkins show to James Watson when Watson visited King’s after having seen the erroneous Pauling three-stranded DNA structure?

He showed Watson Rosalind’s famous DNA photo 51

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28

What was the name of the chemist who straightened out Watson and Crick on the keto and enol structures of the four base pairs?

Jerry Donahue, a theoretical and physical chemist

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29

What is the name for the type of bond that holds the base pairs together?

Hydrogen bonds

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30

Who was pygmalion and why does Crick say that the structural model of DNA is like pygmalion?

He is a figure from Greek myth who fell in love with a stature he carved. Crick made the comparison due to the natural beauty of the DNA structure.

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31

What are the chemical components of a DNA molecule?

phosphate, sugar, and nitrogenous base

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