Controlled Substances Classifications

Schedule I

Are not usually dispensed in pharmacies

High potential for misuse, lack of data for safe use in humans, no current acceptable medical use

Schedule II

Highest potential for misuse and physiological dependence or addiction

Most stringent requirements in pharmacy

Schedule III

Less misuse and addiction potential than Schedule II medications

Schedule IV

Less misuse and addiction potential than Schedule II and III medication

Schedule V

Lowest misuse potential of all controlled substances

Some states allow certain C-V medications to be dispensed without a prescription

Marijuana

C-I

LSD

C-I

PCP

C-I

GHB

C-I

Heroin

C-I

Ecstasy

C-I

hydrocodone combinations (Lortab, Norco, Tussionex, Vicoprofen)

C-II opioid

fentanyl (Duragesic, Actiq, Abstral, Lazanda, Fentora)

C-II opioid

hydromorphone (Dilaudid)

C-II opioid

meperidine (Demerol)

C-II opioid

morphine sulfate (MS Contin, Oramorph, Kadian, Avinza)

C-II opioid

methadone (Dolophine)

C-II opioid

oxycodone (OxyContin, Roxicodone)

C-II opioid

oxycodone combinations (Percocet)

C-II opioid

single-ingredient codeine products

C-II opioid

amphetamine/dextroamphetamine combos (Adderall)

C-II stimulants

dextroamphetamine (Dexedrine)

C-II stimulants

methylphenidate (Concerta, Ritalin, Methylin, Daytrana, Metadate, Quillivant XR)

C-II stimulants

dexmethylphenidate (Focalin)

C-II stimulants

lisdexamfetamine (Vyvanse)

C-II stimulants

buprenorphine (Suboxone, Subutex)

C-III

acetaminophen/codeine (Tylenol #3)

C-III

butalbital/aspirin (Fiorinal)

C-III

testosterone (AndroGel, Androderm, Depo-Testosterone)

C-III

phentermine (Adipex-P)

C-IV

alprazolam (Xanax)

C-IV

clonazepam (Klonopin)

C-IV

lorazepam (Ativan)

C-IV

diazepam (Valium)

C-IV

temazepam (Restoril)

C-IV

triazolam (Halcion)

C-IV

carisoprodol (Soma)

C-IV

modafinil (Provigil)

C-IV

zolpidem (Ambien)

C-IV

zaleplon (Sonata)

C-IV

eszopiclone (Lunesta)

C-IV

phenobarbital (Luminal)

C-IV

codeine combination products with no more than 200 mg codeine/100 mL (Robitussin AC)

C-V

diphenoxylate/atropine combos with no more than 2.5 mg diphenoxylate and not less than 25 mg atropine per dosage unit (Lomotil)

C-V

pregabalin (Lyrica)

C-V

lacosamide (Vimpat)

C-V