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Diabetic w/ anorexia, anemia, wt loss, pallor
Chronic renal failure
Gastroparesis, impotence, recurrent infections, stocking-glove paresthesia
Diabetic neuropathy (Treat w/ TCA (amitriptyline)
Hypoglycemia despite glucose administration. Increased C-peptide
Insulinoma
Hypoglycemia in alcoholic
Give Thiamine before glucose to prevent Wernicke's encephalopathy
Decreased radioactive iodine uptake, decreased free T4, increased TSH
Hashimoto's thyroiditis
Female, weight loss, palpitations, atrial fibrillation
Hyperthyroid (work it up with TSH, T4)
Exopthalmos, palpitations, wt. loss. Elevated radioactive idodine uptake
Hyperthyroid, Graves Dx - Tx w/ Radioactive iodine
Post thyroidectomy - most likely injury
Recurrent laryngeal nerve = hoarseness
Post thyroidectomy - electrolyte watch
Hypocalcemia
Infant w/ round face, large protruding tongue, dry skin, umbilical hernia, constipation, enlarged abdomen, poor feeding, delayed developmental milestones
Congenital Hypothyroidism
"Recurrent HA, HTN not responding to meds, sweating
Attacks of severe HA, HTN, glycosuria
Urinary catecholamines, urinary metanephrines
Pheochromocytoma - Tx pre-op w/ alpha blocker
HTN not responsive to meds
Renal artery stenosis (Infrarenal artery)
HTN w/ hypernatremia, hypokalemia
Primary Aldosteronism
Wt. gain, edema, coarse dry skin, hair, menorrhagia, cold intolerance, hx transphenoidal surgery & radiation
Hypothyroidism
Tetany, hypocalcemia, cataracts
Hypoparathyroidism
Exogenous corticosteroid use
Cushing syndrome
Dexamethasone suppression test
Cushing syndrome
Central obesity, abdominal stria, hyperglycemia, moon facies, buffalo hump, easy bruising
Cushing syndrome
Acute steroid withdrawal
Addison's disease, crisis
Hyperpigmentation, hypoglycemia, orthostatic hypotension, hypotension not responsive to fluids, hypotension following an illness, trauma, or surgery
Addison's disease, crisis (Low aldosterone; get Random or AM cortisol, ACTH stimulation test)
Worsening fatigue, wt loss, weakness, recurrent abdominal pain, hair loss, hyperpigmentation. Hyponatremia, hyperkalemia
Addison's disease, crisis (Low aldosterone; get Random or AM cortisol, ACTH stimulation test)
Hyponatremia, hyperkalemia
Acute adrenal insufficiency (Addison's crisis)
Polyuria, polydipsia. Dilute urine, Hypernatremia
Diabetes insipidus
Concentrated urine. Hyponatremia
SIADH
45,X - low hairline, low set ears, webbed neck, short stature; shield chest, wide set nipples, infertility, lack of Secondary sex characteristics
Turners (gonadal dysgenesis
XXY ♂ - short stature, ↓ intelligence; small firm testes, gynecomastia, abn arm-body length
Klinefelters (hypogonadism)