bone develop,emt

List features of bones that distinguish it from cartilage

internal vascularity curricular system with construction/remodeling and then appositional growth

internal vascular

From her haversian and Volkman canals in the matrix

canalicular system

Allows for communication between cells through the hard matrix and metabolism is increased

reconstruction/remodeling

After birth to give rise to version, Canal systems with the periosteum and endosteum form

Appositional growth

Increase thickness periosteum proliferates to elongate a facial plate grows out from the outer edge and interstitial growth is not possible.

List the two types of bone formation and describe how the process is

Intramembranous and endochondral

Intramembranous

Has no cartilage involved occurs in the flat bones of the skull and clavicle

Endochondral

Uses existing card as a scaffold for bone deposition in long bones

The steps in the realization of bone with hydroxyapetite

calcification, alkaline, phosphatase, high calcium phosphate, concentration, and calcium phosphate

Calcification

where calcium binds to glycol proteins of osteoid

alkaline phosphotase

The increase in calcium concentration, stimulates, alkaline, phosphatase production from osteoplast, releasing phosphate ions

high calcium and phosphate concentration

triggers the release of vesicles containing ALP and Pyro phosphatase, releasing more phosphate ions

calcium phosphate

is crystallized to initiate hydroxyapatite formation

Describing detailed the steps leading to the end of Contro formation, the primary ossification center

form pre-cartilage enlargement vascular, budding, secondary ossification, and if epiphyseal cartilage disappears

describe the process by which bone grows in thickness

appositional growth

Appositional growth

where bone lining cells of the periosteium become active osteoplast osteoplast increased size of cavity by bone reabsorption

Explain how osteoclast and osteoplast work together to remodel bone

haversion systems, osteoplast line, canals, and spatial canals are reduced

haversion systems

Established after birth and cylindrical, canals, dissolved in compact bone by osteoclasts

Osteoplast line canal

Add layers of foam from the outside in words

spacious canals reduced

slender canals left around blood vessels

explain at the basic level, how broken

Blood clots becomes soft callous, fibrocartilage becomes hard callus, spongy bone becomes bone modeling

blood Clot

soft callous formation with granulation tissue

fibrocartilage

becomes hard callus surrounded by spongy bone

remodeling

New compact bone

Explain the role of osteoplast and hormones in the pathogenesis of osteoporosis

bonus porous and weak, it increases osteoplast activity and balances in PTH

bone is porous and weak Due to

imbalance between resorption and formation

increased osteoclast activity

when female hormones inhibit cytokines differentiate osteoclasts

imballences in PTH

increase resorption and calcitonin inhibits the osteoclast