Molecules that assist phagocytes (inflammation)

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4 Terms

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Cytokines (cell signalling proteins)

Attract phagocytes to sites of infection

Histamine stimulates cells to release cytokines

  • stimulate inflammation and immune response

    (Interleukin 1 & 6 promote inflammation)

    (Interleukin 1 = targets brain causing drowsiness and fever)

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Opsonins

Bind to pathogens

Mark them for phagocytosis

(Phagocytes have receptors to bind to opsonins)

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Limitations of non specific defences

  • not always effective

  • Rapid response is same for all pathogens - cants distinguish between pathogens

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