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compound
2+ different elements combined in a fixed ratio
molecule
2+ same or different elements combined in fixed ratio
valence shell
outermost electron shell
valence electrons
electrons in the outermost shell
electrons are most reactive when
the valence shell is incomplete
Chemical bonds
the attractive forces that hold atoms together
covalent bond
a bond formed when atoms share one or more pairs of electrons
nonpolar covalent bond
A type of covalent bond in which electrons are shared equally
polar covalent bond
unequal sharing of electrons, creates partial charges (poles)
ionic bond
strong electrical attraction between two oppositely charged atoms or groups of atoms (cation to anion)
Cation
A positively charged ion
Anion
A negatively charged ion
hydrogen bond
weak attraction between a hydrogen atom and another atom
1st law of thermodynamics
Energy cannot be created or destroyed
2nd law of thermodynamics
Energy cannot be changed from one form to another without a loss of usable energy
endothermic reaction
A reaction in which energy is absorbed
exothermic reaction
A reaction that releases energy in the form of heat
Properties of water
cohesion, adhesion, excellent solvent, solid is less dense than liquid, specific heat, surface tension
Adhesion
attraction between molecules of different substances
Cohesion
Attraction between molecules of the same substance
why can life be sustained in water when the temp is below freezing?
solid is less dense than liquid, ice rises
properties of acids
dissolve in water, increase H+ ion concentration in solution. Smaller # on pH scale
properties of bases
dissolve in water, decrease relative H+ ion concentration in solution. higher # on pH scale
Buffer
compound that prevents sharp, sudden changes in pH. generally brings it to neutral (7)
organic molecules
carbon-based molecules. singular=monomers
plural=polymers
Carbohydrates
C+O+H
monomer= monosaccharide (glucose)
polymer= polysaccharide (starch)
Lipids
fats and oils
hydrophobic
Proteins
Chains of amino acids
monomer= amino acid
polymer= polypeptide (proteins)
peptide bond
Bonds that connect amino acids.
protein functions
enzyme catalysis, defense, transport, support, motion, regulation, storage
neucleic acid
DNA and RNA
monomer= nucleotide
Neucleic acid function
information storage
Nucleotide
monomer of nucleic acids made up of a phosphate group, a nitrogen base, and a sugar (deoxyrobose or ribose)
Adenine
Thymine/Uracil
Cytosine
Guanine
what bonds O and H in a water molecule?
nonpolar covalent bond
Microtubules
Spiral strands of protein molecules that form a hollow tubelike structure.
form mitotic spindle and keep shape
intermediate filaments
Threadlike proteins in the cell's cytoskeleton that are roughly twice as thick as microfilaments
keep organelles in place
microfilaments
Fine, threadlike proteins found in the cell's cytoskeleton. form cellular cortex
lysosome
An organelle containing digestive enzymes
peraxisome
metabolizes waste
Cytoplasm
A jellylike fluid inside the cell in which the organelles are suspended
cell membrane
the selectively permeable lipid membrane surrounding the cytoplasm of a cell.
Nucleus
Control center of the cell
stores and protects DNA, makes RNA and ribosomes
Ribosomes
protein synthesis
made of RNA and Proteins
protein synthesis
The creation of a protein from a DNA template.
Endoplasmic Reticulum (ER)
A cell structure that forms a maze of passageways in which proteins and other materials are carried from one part of the cell to another.
makes lipids
detoxing
Golgi apparatus
modifies, packages, stores, and transports lipids made by Smooth ER
Mitochondria
Powerhouse of the cell
Chloroplast
Site of photosynthesis
Meiosis
forms 4 haploid cells
Meiosis I
same as mitosis
Prophase 1, Metaphase 1, Anaphase 1, Telophase 1, Cytokinesis
Meiosis II
Meiosis 1 again.
Prophase 2, Metaphase 2, etc.
end up with 4 haploid (1n) cells
Watson and Crick
Developed the double helix model of DNA.
Process of Replicating DNA
1. enzyme Helicase breaks nucleotide bonds, unwinding double helix
2. enzyme DNA polymerase reads sequence of nucleotides on DNA strand
3. Polymerase builds new strand by matching nucleotides (A to T, C to G)
4. 2 DNA strands :)
Mutation
A change in a gene or chromosome.
Substitutions-wrong nucleotide (A instead of C, etc)
Frameshifts-extra nucleotide added/essential one deleted
gene
A segment of DNA on a chromosome that codes for a specific trait
Transcription
synthesis of an RNA molecule from a DNA template
DNA to RNA
Translation
sets of 3 nucleotides on mRNA, form codons
Codon
three-nucleotide sequence on messenger RNA that codes for a single amino acid. complimentary to anticodons (A to U, etc.)
Ribosomes match codons to anticodons. add amino acids=proteins
structural genes
genes that code for proteins
regulatory genes
code for regulatory proteins
regulate growth, development, start/stop transcription of certain genes
bacterial genes
no nucleus
DNA changed easily, quickly become resistant to medication
Transduction
viruses transfer genes between prokaryotes
Transformation
Bacteria take DNA right from environment
Viruses
Viruses can only reproduce inside host cells, and they damage the cell when they do this
have own DNA
Virus structure
DNA or RNA molecule with a protein coat for protection, the shape is created by its protein coat
some have enzymes
viral infection
1. Invades cell
2. Inserts genetic material
3. Viral genes direct host cell to make more virus parts
4. Virus multiplies
5. Mature virus leaves, rupturing membrane (kills cell)
what part of the cell membrane is fluid and can move past other membrane components?
lipids and proteins
hypotonic cell
loses water
what limits animal cell growth?
ratio of cell surface to cell volume
how do neurotransmitters enter the synapse?
exocytosis
Cytoskeleton
A network of fibers that holds the cell together, helps the cell to keep its shape, and aids in movement. centromere is in its "family"
microfilaments help support
cell wall
strong, supporting layer around the cell membrane in some cells composed of cellulose, pectin, and chitin
centrosomes
Microtubule-organizing centers that help to form and organize the mitotic spindle during mitosis.
Microtubules are largest filaments
Intermediate filaments are durable
Vesicles
sacs made of membrane that can fuse with another cell's membrane
Vacuole
A sac inside a cell that acts as a storage area
passive transport
diffusion across a membrane requiring only the random motion of molecules with no energy expended by the cell
active transport
Energy-requiring process that moves material across a cell membrane. requires "doorway" protein
Diffusion
Movement of molecules from an area of higher concentration to an area of lower concentration. passive transport.
Osmosis
diffusion of water
bulk transport
endocytosis and exocytosis
Endocytosis
entering the cell through vesicles
Exocytosis
exiting the cell through vesicles
prokaryotic cell
Bacteria and Archaea
no nucleus
unicellular
eukaryotes
animals, plants, fungi, protists
have cell membrane, organelles, DNA
uni or multicellular
activation energy
Energy needed to get a reaction started
Enzymes
proteins that act as biological catalysts
only function in living cells
Substrate
A specific reactant acted upon by an enzyme
active site
A pocket or groove on the surface of the enzyme.
where the substrate reacts
Coenzymes
enzyme helpers
usually vitamins
Cosubstrates
detachable coenzymes
organic
prosthetic group
permanent coenzyme
organic
inorganic cofactors
metal ions
organic cofactors
coenzymes
Inhibitor
molecule that binds to a protein (usually an enzyme) and keeps it from functioning by inhibiting substrate reaction
can change active site shape
Denaturation
change in enzyme shape that makes it not work
regulation
cell controls the action of its own enzymes
can use inhibitors
controls active site shape
cellular respiration
converting food (glucose) into energy (ATP)
steps of cellular respiration
1. Glycolysis
2. Pyruvate Oxidation
3. citric acid cycle
4. Electron Transport Chain