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what are the 3 primary wall layers for vessels?
1. tunica Intima (innermost)
2. Tunica Media (middle)
3. Tunica Adventitia (outermost)
which vessel wall layer has thin epithelial cells?
Tunica intima
which vessel wall has a muscular layer?
Tunica Media
which vessel wall is used as a protective layer?
Tunica Adventitia
Why are vessels easier to compress?
Because arteries have thicker vessel walls than veins
What are some similarities that veins and arteries have?
Both have 3 layers of walls
Both carry blood
What are some differences with veins and arteries? (5)
1. Artery walls are thicker/ more muscular
2. Venous walls are thinner and more pliable. compressible
3. Veins can have valves
4. Arteries pulsate while veins collapse with breathing/ respiratory
5. Arteries take blood from heart to the body while veins take blood from the body to the heart
How many segments does the aorta have and what are they?
5 segments;
1. ascending
2. arch
3. descending
4. thoracic
5. abdominal
TRUE OR FALSE:
The abdominal aorta lies in the retroperitoneum and tapers in size as it gets more distal
true
what are the branches off of the abdominal aorta?
celiac trunk, superior mesenteric artery, renal arteries, inferior mesenteric artery, common iliac arteries
what are the branches coming off of celiac trunk/axis?
1. Hepatic artery
2. Left gastric Artery
3. Splenic
Hepatic Artery
supplies blood to the liver;
travels superior to pancreatic head then turns right and meets PV
Gastroduodenal artery (GDA) branches off of hepatic
What are the variations of Hepatic Artery? 3 different types
Type 1: "normal" branching pattern in which the hepatic Artery branches off of the Celiac trunk
Type 2: Replaced Left Hepatic artery; The LHA branches off the Left gastric Artery
Type 3: Replaced Right Hepatic artery; RHA branches off the SMA, while the LHA branches off of the celiac trunk
left gastric artery
supplies blood to stomach and esophagus
branches anteriorly and superiorly in a leftward direction.
What are some variations that left gastric artery
can arise from hepatic artery or splenic artery
Splenic artery
supplies spleen, stomach, and pancreas
branches laterally toward the left and runs posterior and superior to pancreatic body and tail.
Superior Mesenteric Artery (with variant)
supplies blood to the small and large intestine; blood flow changes depending on fasting
Can share a trunk with celiac
Renal Arteies
Supplies blood to kidneys, ureter and adrenal glands
inferior to SMA, The right renal artery originates postero-lateral and runs posterior to the IVC before reaching the kidney. The left renal artery originates laterally and runs directly toward the kidney.
Inferior mesenteric artery
Supplies the descending large intestine, sigmoid colon, and rectum
Common iliac arteries
supplies pelvis and lower limbs
Arteries have branches while veins have
tributaries
Inferior Vena Cava (IVC)
Delivers blood from lower extremities, pelvis and abdomen to the right atrium; lies right of the aorta
azygos and hemiazygos veins
lie on either side of the thoracic vertebral bodies and return blood from the chest wall and drain into the superior vena cava
Only see these if they are dialated
Tributaries of IVC
common iliac veins, lumbar veins, right gonadal vein, right renal vein, right suprarenal vein, inferior phrenic vein, hepatic veins
Which renal artery is longer and why?
Right renal artery is longer because the Aorta and abdominal aorta are left side structures; meaning that it would have to pass behind IVC to reach the right kidney
Which renal vein is longer and why?
Left renal vein is longer because the inferior vena cava is on the right side
LRV runs ________ to aorta and ________ to SMA
anterior; posterior
Renal veins
Drains the kidneys. Empties directly into the inferior vena cava.
hepatic veins
drain blood from the liver to return to the heart;
LHV: drains left lobe
RHV: right lobe
MHV: caudate lobe
Portal tributaries
Portal vein, SMV,splenic vein, IMV, cystic vein, gastric vein, pancreaticoduodenal, and paraumbilical vein
Portal vein is special because:
its taking blood to the liver rather than draining to return to the heart
porta hepatis
where the blood and lymph vessels, bile ducts, and nerves enter and leave the liver
portal confluence
where the SMV and splenic vein come together to make the main portal vein
Why do we do an aorta sonogram?
Hypertension, History of aneurysms, masses on aorta
why do we have an IVC sonogram?
Hydration/volume status, heart failure, concern for thrombus, guidance and placement of clot catching device
Normal AP and Width measurements of the aorta
Proximal Aorta = 2.5 cm
Distal Aorta = 1.5 cm
What is the nutcracker phenomenon?
a variant of the SMA; occurs when the left renal vein is significantly compressed between the aorta and SMA
Abdominal Aorta scanning Protocol: Patient Prep
· Fasting 6-8 hours to reduce overlying bowel and gas
· Eating should not prohibit exam- still attempt
· Emergent studies do not require fasting
· Patient is supine
· Curvilinear mid-low frequency transducer
Abdominal Aorta scanning Protocol: Long/ Sag images
· Sweeping left to right all the way through the aorta at all segments to identify abnormalities
· Sagittal proximal aorta with and without AP measurement (2-3 images)
· Sagittal mid aorta with and without AP measurement (2-3 images)
· Sagittal distal aorta with and without AP measurement (2-3 images)
· Coronal iliac bifurcation (1 -2 images) with color if needed
· Sagittal right and left common iliac arteries with AP measurements (2-4 images)
· Doppler as indicated by exam concern
Abdominal Aorta scanning Protocol: Trans Images
· Sweeping superior to inferior all the way through to the bifurcation to identify abnormalities
· Proximal with and without AP measurement (2)
· Celiac and SMA origins (1-2 images) color as needed
· Mid at level of renal arteries showing renal artery bifurcations (2-4)
· Mid with and without AP measurement (2)
· Distal with and without AP measurement (2)
· Distal bifurcation with iliacs (1-2)
· Rt and Lt iliacs trans with and without measurements (2-4)
Inferior Vena Cava Scanning Protocol: Patient prep
· Fasting 6-8 hours to reduce overlying bowel and gas
· Eating should not prohibit exam- still attempt
· Emergent studies do not require fasting
· Patient is supine (LPO and/or LLD if needed)
· Curvilinear mid-low frequency transducer
· Normal respiration if possible (***When patient takes in a deep breath and holds it, the IVC will decrease in size or collapse due to pressure changes in the abdomen.)
Inferior Vena Cava Scanning Protocol: Long/sag images
· Sweeping through the vessel from right to left at different levels to identify abnormalities
· Proximal/Intrahepatic portion of the liver (1-2)
· Mid IVC at level of the renal veins (2-4)
· Distal IVC (closest to umbilicus) (1-2)
· Distal bifurcation with Iliac veins/Sagittal right and left common iliac veins (2-4)
Inferior Vena Cava Scanning Protocol: trans images
· Sweeping through the vessel from superior to inferior to identify abnormalities
· Proximal IVC including (intra)hepatic vein branching (1-2)
· Mid IVC at level of the renal veins (1-2)
· Distal IVC, just above where the iliac veins meet to form IVC (1-2)
· Common Iliac Veins (1-2)
what is the biliary system composed of directly and indirectly?
Directly: gallbladder and bile ducts
Indirectly: liver and GI system
What is cholecystokinin? (CCK)
CCK is a hormone that triggers the gallbladder to contract to release bile into ducts; response to the presence of chyme.
the gallbladder is ______, which means it is outside of the liver
extrahepatic
what is the location of the gallbladder
within the main lobar fissure BTW right and left lobes of the liver
what are the components of the GB
1. Fundus: Widest portion; May project from inferior edge of liver
2. Body: Main part, In contact with liver
3. Neck: Narrowest area; Narrows to become Cystic duct which connects GB to common hepatic duct
Spiral valves of Heister (supportive, not functional
function of the gallbladder?
Stores, concentrates and releases bile into the GI system to emulsify fat/lipids
what are the layers of the gallbladder made out of?
inner layer = epithelial mucosa
middle layers = muscular and subserous
outer layer = serosa adventitia
The common bile duct is made up of
common hepatic and cystic duct
Portal triad
portal vein, hepatic artery, bile duct
biliary tree
intrahepatic ducts
Can we live without a gallbladder, why or why not?
we can live without one because the ducts can take over and store bile
What are the anatomical relationships of the gallbladder?
GB is lateral to
GB is anterior to
Lateral: 2nd part of duodenum
Anterior: Right Kidney and Transverse colon
biliary system function
concentrates and stores bile (GB, CBD, after cholecystectomy)
What are the components of bile? (6)
1. Bilirubin (main one)
2. Cholesterol
3. Bile Salts
4. phospholipids
5. water
6. electrolytes
what is the function of bile?
helps to break down/ emulsify lipids/ fats into smaller pieces so thats they can be absorbed bot the digestive tract
what is bilirubin?
pigment in bile
when RBC' break down, they are taken from the bloodstream by the liver and processed into:
Bilirubin
Direct bilirubin
Conjugated with glucuronic acid, water soluble
Indirect bilirubin
Unconjugated, water insoluble
In the GI tract, the bilirubin within the bile is acted on by bacteria that convert it to
urobilinogen
Back-up of bilirubin will cause
Jaundice because extra bilirubin will get into the bloodstream;\
What is the shape of the gallbladder
pear-shaped
what is the AP/Width at Mid normal measurements of GB
< 4 cm
Anterior wall thickness at mid normal
< 3mm
Gallbladder wall measurement with ascites
< 4 mm
Intrahepatic ducts diameter
< 2mm
What is a phrygian cap
folding of the fundus of the gallbladder
What is Hartmann's pouch?
an outpouching of the gallbladder neck
what is.a gallbladder duplication
when there is an extra GB
Why physicians order gallbladder sonograms
1. Congenital anomalies that are seen prenatally
2. Epigastric pain
3, RUQ pain
4. Jaundice
5. Nausea and vomiting
6. Abnormal lab values
7. abnormal findings on other imaging studies
Length of the Gallbladder
10-13 cm
Capacity of the gallbladder
30-50 ml
Cystic ducts measures _____ length
2-4 cm
Bile duct width measurements
Normal: 4-6 mm
Gallbladder Patient prep
· Patient is fasting (NPO) at least 8 hours to distend GB
· NPO at least 4 hours if patient has cholecystectomy
· Evaluate patient in minimum of two different patient positions
o Supine
o Left lateral decubitus (LLD)
In this position, patient can position right arm over their head for better rib access
o Upright can be used if needed
· Use held inspiration and expiration to bring GB into view
· Lower frequency curved (preferred) or sector transducer
· Higher frequency on thin patients, pediatric patients
Gallbladder Protocol: Longitudinal Images
While patient is SUPINE
· Sweep from lateral to medial all the way through the GB to identify any abnormalities
· Representative sagittal images (3-6) typical
· Midline length measurement here if required, taking one with and without calipers
· Lateral
· Medial
· Document and measure common bile duct. If unable to see it supine, take this picture in the LLD position
· Repeat the protocol with patient in LLD position
Gallbladder Protocol: Transverse Images
While patient is SUPINE
· Sweep superiorly to inferiorly all the way through GB in both directions to determine presence of pathology
· Representative transverse images, Mid, superior, inferior
· Alternatively labeled, body, fundus, neck
· Measure GB wall at transverse mid, picture with and without calipers
o Try to clear
· Repeat the protocol with patient in LLD position
Why would a doctor order a liver sonogram (6)
If the patient had the following symptoms:
1. RUQ pain
2. Elevated liver enzymes (LFTs)
3. Jaundice
4. Follow-up on known liver abnormalities
5. screening for those with hepatic disease
6. evaluating abnormalities noted on other imaging studies
In embryology, what is developed in the 4th week RUQ
Liver, gallbladder, bile ducts
In embryology, what is developed in the 5th week RUQ
Differentiation: Cystic duct, gallbladder, Right and Left hepatic lobes, Bile duct system
In embryology, what is developed in the 6th week RUQ
right and left hepatic lobes are formed
In embryology, what is developed in the 6th + week RUQ
Hemopoiesis; formation of cellular components of blood
Bile: liver involvement indigestion after birth
Umbilical vein left branch is what after birth
Ligamentum teres
Umbilical vein right branch is what after birth
Ligamentum venosum
What is the 3 main cell types for the liver
1. Hepatocytes: male up the liver parenchyma, are useful for metabolism
2. Biliary Epithelial Cells: For bile creation
3. Kupffer cells: phagocytic cells that eat up debris
Damage to the cells in the liver can cause
alter liver enzymes
What are the major functions of the liver? (8)
1. Bile formation and secretion
2. Metabolism of carbohydrates, fats, proteins
3. Immunity and phagocytosis
4. Storage for vitamins, glucose, iron, fats, amino acids/protein
5. Blood resivor
6. heat production
7. Detoxification and metabolism of drugs and hormones
8. Lymph formation
what are the basic functional unit of the liver
hepatic lobules
What is the liver lobules composed of?
Hepatocytes
kupffer cells
centra; vein
sinusoids
portal triad
liver parenchyma is known as
the meat of the liver
What is Reidel's lobe?
a normal variant of the liver where the right lobe extends far below right kidney
Situs inversus
complete reversal of all abdominal organs
what is the largest organ in the abdomen?
LIver; ·
13-15 cm length midclavicular
17 cm intercostally
1400-1600 grams
AP: 10-12.5 cm
Transverse/width 20-22.5cm
in the liver, what is filled with blood
sinusoids
What are the main 2 vessels used for blood supply to the liver
Portal vein and Hepatic artery
ligamentum teres
appears as bright echogenic foci on transverse image; along with falciform ligament, it divides medial and lateral segments of the left lobe of the liver
ligamentum venosum
separates the left lateral lobe from the caudate lobe; seen better in sagittal