Localization
The idea that different brain areas have specialized functions.
Equipotentiality
The idea that the brain functions as a whole, and any part can perform any function.
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Localization
The idea that different brain areas have specialized functions.
Equipotentiality
The idea that the brain functions as a whole, and any part can perform any function.
Phrenology
The outdated theory that skull bumps indicate mental traits.
Cognition
Mental processes like thinking, memory, and perception
Neuroscience
Study of the nervous system
Cognitive Neuroscience
Intersection of both fields, studying how brain function supports cognition
Dualism
The belief that the mind and body are separate entities (Descartes).
Empiricism
The idea that knowledge comes from experience and observation.
Neuron Doctrine
The theory that neurons are individual units that communicate via synapses.
Cajal used Golgi’s staining method to develop Neuron Doctrine and proposed that the nervous system is made up of discrete, individual cells.
Fritsch & Hitzing
Electrical stimulation of the brain (motor cortex) affects movement (motor map in dogs)
Cytoarchitectonics
Brodman, structural arrangment of neurons, based only off of morphological properties
Ventricles
Cavities in the brain that contain cerebrospinal fluid (CSF) that cushions and nourishes the brain, regulate pressure, shock absorption.
Lobes of the Brain
Frontal, Parietal, Occipital, Temporal
Frontal Lobe
primary motor cortex, thinking, movement, most complex, decision making
includes Prefrontal Cortex (planning, attention) and Orbitofrontal Cortex (personality, damage = antisocial behavior)
Occipital Lobe
primary visual cortex, vision, back of head
Temporal Lobe
primary auditory cortex, hearing, Wernicke’s area, face & object recognition, located on the sides of the brain
Parietal Lobe
primary somatosensory cortex, touch, perception of spatial movement, located above the occipital lobe
Subcortical structures
group of brain regions located beneath cerebral cortex
Parts of Neuron
Include the Soma (cell body), Dendrites (input), and axon (output), Myelin (insulation), which are essential for transmitting signals.
Gray Matter
cell bodies (contains neurons and synapses)
White Matter
axon tracts (contains myelinated axons for communication), myelin is white
Why is the cortex folded?
large surface area in small space, decrease in axonal distance & connection time
Transverse Orientation
Top-down view of the brain.
Sagittal Orientation
Side view of the brain.
Coronal Orientation
Front view of the brain.
Rostral/Anterior
towards front
Caudal/Posterior
towards back
Dorsal/Superior
towards top
Ventral/inferior
towards bottom
Astrocytes
Glial cells that support and nourish neurons, keep out bacteria, maintain BBB.
Oligodendrocytes
Glial cells that create myelin in the CNS.
Schwann Cells
Glial cells that create myelin in the PNS.
Microglia
Glial cells that serve immune defense, synaptic pruning, remove damages cells.
Ions involved in Neuronal Signaling
Sodium (Na+), potassium (K+), chloride (Cl-), calcium (Ca2+).
Layers of the Brain
Skull, dura mater (protective layer, hard), gray matter (neurons), white matter (axons).
Cerebellum Function
Coordination, balance, and fine motor control, highly complex, most neurons
Limbic System
Responsible for emotion and memory; includes the basal ganglia, amygdala, and hippocampus.
Importance of Redundancy in Brain Arteries
Ensures continuous blood flow in case of blockage (e.g., stroke prevention).
Gyrus (Gyri)
bumps
Sulcus (Sulci)
grooves
Spatial Resolution
The ability to see where brain activity occurs.
Temporal Resolution
The ability to see when brain activity occurs.
Cognitive Psychology
The study of mental processes like memory, attention, and perception.
Computational Modeling
simulation, using computer as metaphor for brainto understand cognitive processes and behavior.
Neuropsychology
Studying brain function by examining brain injuries.
Coup
Initial impact on the cortical surface of the brain
Countercoup
Brain bounces back, can be worse than coup
fMRI Pros and Cons
✅ High spatial resolution. ❌ Low temporal resolution (slow).
Two Types of fMRI design
Block design & Event-related design
EEG
Measure of electrical activity, changes in voltages, non-invasive electrodes
✅ High temporal resolution. ❌ Poor spatial resolution.
ERP
Event related potential, type of EEG analysis
MEG
magnetic fields fro, brain activity, average ERPs, more accurate spatial localization
BOLD Signal
Blood Oxygen Level Dependent signal, indicating neural activity.
CT Scan
Use of x rays to create images of internal brain structures (only spatial)
MRI
magnetic fields for structure, changing concentrations of protons, only structural
Single Dissociation
One function is impaired, but another is not.
Double Dissociation
Two independent functions are affected differently.
TMS
A technique that temporarily disrupts brain function using magnetic pulses, allows for double dissociations.
Single cell Recording
insert electrode into neuron and record action potentials, excellent spatial AND temporal resolution, but poor spatial COVERAGE (one neuron only)
Retinotopic Mapping
The way the visual field is represented in the brain.
Receptive Fields
The area of the visual field that a neuron responds to.
V1
Primary visual cortex, detects edges, oriented lines
V5 (MT)
motion detection, movement/speed
V4
color processing, attention
Lateral Geniculate Nucleus (LGN)
thalamus relay for vision, begins processing of visual info from retina, between retina & V1
Olfaction
The sense that does NOT pass through the thalamus first.
Tonotopic Map
Auditory system organizes sound frequencies, high frequencies = base, low = apex.
Interaural Time Difference
sounds reach closer ear first
Interaural Intensity Difference
sound louder in closer ear
Medial Geniculate Nucleus (MGN)
thalamus relay for audition, between inferior colliculus and auditory cortex
Ventral Posterior Nuclear Complex
relay of thalamus for sensory (touch) information, thalamus → cerebral cortex
Cortical Plasticity
The brain’s ability to reorganize itself after injury.
Corpuscles
receptors in the skin
Merkel’s Corpuscles
regular touch
Meissner’s Corpuscles
light touch
Pacinian Corpuscles
deep pressure
Ruffini Corpuscles
temperature information
Nociceptors
signal pain via myelinated and unmyelinated fibers
Proprioceptors
at linkages of muscles and tendons provide physical state
Synesthesia
A condition where stimulation of one sense leads to experiences in another (e.g., seeing colors when hearing music), mixing of 2 or more senses
Phantom Limb Syndrome
Feeling sensations in a missing limb, often treated with mirror therapy.
Taste Transmission
Taste buds → brainstem → thalamus → gustatory cortex.
Studying Olfactory Sensation in fMRI
Difficult because breathing motion interferes with imaging.
Olfactory Receptors
Hundreds exist, each responding to different odor molecules.
Which sense does not predominantly project contralaterally?
Gustation