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do fish have a single or double circulatory system
single.
the heart pumps blood to the gills to pick up oxygen
blood flows directly from the gills to the rest of body to deliver oxygen
how does the double circulatory system in mammals occur
the right side of the heart pumps deoxygenated blood to the lungs to pick up oxygen
the left side of the heart pumps oxygenated blood to the rest of the body.
what group of animal have closed circulatory systems
vertebrates
what happens in a closed circulatory system
blood is contained in vessels
arteries generally distribute oxygenated blood
veins generally distribute deoxygenated blood to the heart
what group of animals have open circulatory systems
invertebrates like insects
what happens in an open circulatory system
blood flows freely through the body cavity
blood returns to the heart through valves
blood odesn’t just transport oxygen
what is the difference between the systemic and pulmonary circulation systems
in systemic circulation: (heart-body-heart)
oxygenated blood is pumped out of heart via the aorta to the body tissues
deoxygenated ir returned to the heart via the vena cava
in pulmonary circulation: (heart-lungs-heart)
deoxygenated blood is pumped out of the heart via the pulmonary artery to the lungs
oxygenated blood is returned to the heart via the pulmonary vein
what is the function of arteries
carry blood away from the heart at high pressure
what is the function of arterioles
carry blood from arteries into capillaries
what is the function of capillaries
site of diffusion between blood and body tissues
what is the function of venules
carry blood from capillaries to veins
what is the function of veins
return deoxygenated blood to the heart at low pressure
what are the adaptations of arteries for carrying blood at high pressure
collagen- provides strength to prevent the vessel from bursting and to maintain vessel shape
elastic fibres- contain elastin that lets them stretch and recoil to minimise changes in pressure
thick smooth muscle layer- contracts/ relaxes to constrict/dilate the lumen and control blood flow
why do the walls of arterioles have more smooth muscle and less elastin than arteries
they do not need to withstand such high pressures
how do arteries and arterioles vasoconstrict
smooth muscle contracts, constricting the blood vessel and reducing blood flow
how do arteries and arterioles vasodilate
smooth muscle relaxes, dilating the blood vessel and increasing blood flow
what are the adaptations of capillaries
lumen is very narrow- allows red blood cells to be close to body cells
walls are thin- substances can be exchanged across a short diffusion distance
highly branched- provides a large surface area for diffusion
what are the adaptations of veins for carrying blood at low pressure
collagen- provides strength to prevent the vessel from bursting and maintain vessel shape
little smooth muscle and elastic fibre- not much is needed due to low blood pressure, and thinner walls allow veins to be easily compressed, aiding the flow of blood
valves- prevent backflow of blood when veins are squeezed by surrounding skeletal muscle
do venules contain valves
yes, however venules are smaller than veins
what is the composition of blood
plasma- mostly water, transports substances in solution
red blood cells- carry oxygen
white blood cells- immune cells
platelets- involved in clotting
where is tssue fluid located
is fills spaces between cells
what are the differences in composition of tissue fluid and plasma
tissue fluid has no red blood cells
tissue fluid has fewer proteins
tissue fluid has fewer white blood cells
at the arteriole end of capillaries, there is a high hydrostatic pressure in the capillaries due to the force of the heart pumping. What effect does this have
fluid is forced out of capillaries, forming tissue fluid surrounding cells
at the venule end of capillaries, what is responsible for exerting a high oncotic pressure
proteins in the blood
at the venule end of capillaries, what does a high oncotic pressure in the blood and a low water potential in the capillaries cause
since the water potential is higher in the tissue fluid, some tissue fluid moves back into the capillaries by osmosis
what is some difference in the composition of lymph and tissue fluid
lymph has less oxygen and nutrients
lymph has more fatty acids
lymph has more white blood cells (lymphocytes)
simply, what is lymph formed from
tissue fluid
how is lymph formed
some tissue fluid doesn’t re-enter the capillaries
instead, it drains into lymph vessels, forming lymph
how is lymph transported around the body
it is transported through lymph vessels by muscle contractions
it is passed through lymph nodes to filter pathogens
it is eventually returned to the blood
how is oxygen transported from the lungs to body cells
in the capillaries in the lungs, oxygen binds to iron in haem groups forming oxyhaemoglobin
each haemoglobin molecules can carry 4 oxygen molecules, one per haem group
oxyhaemoglobin can be transported via blood to respiring body tissues
at body cells, oxygen dissociates from haemoglobin
how does a high partial pressure affect haemoglobin saturation with oxygen
at high partial pressure, haemoglobin has a high affinity for oxygen and binds with it.
where in the body is there a high partial pressure and haemoglobin has a high affinity for oxygen
in the lungs
how does a lower partial pressure affect haemoglobin saturation with oxygen
haemoglobin has a low affinity for oxygen and releases it.
where in the body is there a low partial pressure and haemoglobin has a low affinity for oxygen
respiring body cells
in what instances does haemoglobin change shape during cooperative oxygen binding
when haemoglobin binds with oxygen, it changes shape so that it is easier to bind to other oxygen molecules
when haemoglobin is mostly saturated with oxygen, it changes shape so that it is harder for more oxygen to bind
why does fetal haemoglobin have a higher affinity than adult haemoglobin
it allows oxygen to dissociate from the mother’s haemoglobin so that it can bind with haemoglobin in the fetal blood.
it ensures that the fetus has enough oxygen to survive while it develops
describe the Bohr effect
haemoglobin has a lower affinity for oxygen at higher partial pressures of carbon dioxide.
more indepthly
higher p(CO2) at respiring tissues causes haemoglobin to release oxygen
this means the oxygen saturation of haemoglobin is lower for a given p(O2) when p(CO2) is higher
why is the Bohr effect needed
because actively respiring tissues that produce carbon dioxide require a lot of oxygen from the blood. The Bohr effect shifts the oxygen dissociation curve to the right, causing oxygen to dissociate more readily
why is it useful for CO2 to be converted into another form in the blood
because it maintains a steep diffusion gradient between respiring tissues and the blood, which need to get rid of CO2.
what are some alternate ways that CO2 can be transported via the blood
dissolved in plasma
some CO2 enters red blood cells, and is transported bound to haemoglobin as carbaminohaemoglobin
how is CO2 converted to hydrogen carbonate ions
CO2 reacts with water to form carbonic acid (H2CO3), catalysed by the enzyme carbonic anhydrase
H2CO3 dissociates to H+ and HCO3-
how is the Bohr effect caused
once H2CO3 dissociates to form H+ and HCO3-, H+ binds to haemoglobin forming haemoglobonic acid, causing haemoglobin to release oxygen
this means that at high p(CO2), haemoglobin releases oxygen so it can diffuse into respiring tissues.
how is the chloride shift caused
HCO3- ions leave red blood cells and are transported via plasma, while chloride ions enter red blood cells
this is called the chloride shift, and it maintains the charge balance by preventing excessive positive charge in red blood cells
what is the enzyme called that catalyses the reaction between water and CO2
carbonic anhydrase
how is pH in the blood stopped from becoming too acidic
H+ ions bind to haemoglobin forming haemoblobonic acid
at areas in the body with low p(CO2), what happens to HCO3- and H+ ions
in the lungs for example, low p(CO2) causes HCO3- and H+ to reform CO2
CO2 diffuses out of the body during expiration
what are the differences between the atria and the ventricles
atria- the top chambers of the heart that collect blood from blood vessels (veins)
ventricles- the bottom chambers of the heart that pump blood into blood vessels (arteries)
why does the heart need two seperate pumping mechanisms (one on each side of the heart)
blood pressure drops in the lungs as it flows through the capillaries
a single pump would slow the blood flow to the body cells
two pumps increases the pressure before the blood circulates
what is the function of the septum
it seperates the two sides of the heart, preventing oxygenated and deoxygenated blood from mixing
where are the two atrioventricular valves located
the tricuspid valve is located between RA and RV
the bicuspid valve is located between LA and LV
(they prevent the backflow of blood into the artia)
where are the semi-lunar valves located
between the ventricles and the pulmonary artery and the aorta (they prevent the backflow of blood into the ventricles)
why are ventricle walls thicker than atria walls
the atria only need enough pressure to pump blood a short distance into the ventricles
whereas, the ventricles need a lot of pressure to pump blood a long distance out of the heart to other organs
what ventricle wall is thicker, and why
the left ventricle wall is thicker than the right because…
the right ventricle only needs enough pressure to pump deoxygenated blood a short ditance to the lungs
whereas, the left ventricle needs a lot of pressure to pump oxygenated blood to more distant ograns in the body
name the three stages of the cardiac cycle
atrial systole
ventricular systole
diastole
what happens during Stage 1 of the cardiac cycle, atrial systole
the ventricles relax, and the atria contract
this increases atrial pressure
the atrioventricular valves open
blood flows into the ventricles
when happens during stage 2 of the cardiac cycle, ventricular systole
the vetricles contract, and the atria relax
ventricular pressure increases
the semi-lunar valves open, and the atrioventricular valves close
blood flow into the arteries
what heppens during stage 3 of the cardiac cycle, diastole
the ventricles and atria relax
the semi-lunar valves close
blood flows passively into the atria
what does cardiac muscle being myogenic mean
it means that the contraction of cardiac muscle initiates within the heart itself
in what order does the electrical wave travel through the heart
sinoatrial node (SAN)- intiates the heart beat by stimulating the atria to contract
layer of collagen fibres prevent direct electrical flow from the atria to the ventricles
atrioventricular node (AVN)- picks up the electrical activity from the SAN and imposes a slight delay
Bundle of His- receives electrical activity from the AVN and conducts a wave of excitation to the base of the heart (apex)
Purkyne Fibres- these branch off the bundle of His, causing the right and left ventricles to contract from the bottom upwards
what wave represents atrial systole
P wave
what wave reresents ventricular systole
QRS wave
what wave represents diastole
T wave
define tachycardia
an abnormally rapid heart rate
define bradychardia
an abnormally slow heart rate
define ectopic heartbeats
extra heartbeats out of the normal rythmn
define atrial fibrillation
the abnormally rapid and ineffective contraction of the atria