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ectoderm
the CNS develops from which embryonic layer?
1. neural plate is formed by the ectoderm
2. neural plate fold, forming the notochord
3. neural plates elevate
4. final folding of the neural plates form a neural tube, which forms the CNS
5. cells excluded from the tube are called neural crests, which later form the PNS
describe the steps of CNS formation demonstrated in this image.

neural tube
what is the structure formed by the folding of the neural plate that becomes the CNS?
the neural tube
what is this structure?

neural tube
which part becomes the CNS?

neural crest
which part becomes the PNS?

a cavity in the neural tube filled with fluid. it always remains
what is the sulcus limitans?

3 vesicles that later become 5 vesicles (later forming the brain); the spinal cord
the cranial end of the neural tube forms __________, while the caudal end of the neural tube forms _________
forebrain, midbrain, hindbrain
1. Telencephalon
2. Diencephalon
3. Mesencephalon
4. Metencephalon
5. Myelencephalon
as the cranial end of the neural tube develops, it forms 3 main vesicles, called the ________, ___________, and _________. then, they further develop into 5 vesicles. what are they called?
the cerebrum
what does the telencephalon become?

telencephalon
which vesicle becomes the cerebrum?

the thalamus and hypothalamus
what does the diencephalon become?

the diencephalon
which vesicle becomes the thalamus and hypothalamus after birth?

mesencephalon
which vesicle becomes the midbrain?

midbrain
the mesencephalon becomes the.....

myelencephalon
which vesicle develops into the medulla oblongata?

medulla oblongata
what does the myelencephalon become?

metencephalon
the pons and cerebellum arise from which embryonic vesicle?

pons and cerebellum
the metencephalon becomes the _____ after birth

2 lateral ventricles in the cerebrum
third ventricle in the diencephalon (thalamus/hypothalamus)
cerebral aqueduct in the midbrain
fourth ventricle in the brain stem
where do the neural canals exist in the adult brain?
diencephalon (thalamus and hypothalamus)
where is the third ventricle located?
brain stem
where is the fourth ventricle located?
in the midbrain
where is the cerebral aqueduct located?
the most cranial part of the brain
where is the olfactory bulb?
cerebrum
what is 1?

thalamus
what is 2?

2
where is the thalamus?

hypothalamus
what is 3?

3
where is the hypothalamus?

cerebellum
what is 4?

midbrain
what is 5?

brain stem
what is 6?

PNS:
sensitive ganglia
sympathetic ganglia
parasympathelic ganglia
schwann cells
the neural crests become..
membranes that protect the brain and spinal cord
what are the meninges?
dura mater
the outer meninges is the ______
subarachnoid space
the cavity in between the arachnoid and pia mater is called the _______
dura mater
arachnoid
pia mater
what are the meninges layers, from external to internal?
a congenital disorder where the CSF content in the brain ventricles increase (due to either increased CSF production or a blockage in the draining system). leads to increased pressure on brain tissue
what is hydrocephalus?
brachiocephalic breeds
what breeds are more prone to hydrocephalus?
hydrocephalus
what congenital disorder does this puppy have?

hydrocephalus
what congenital disorder does this cow have?

hydrocephalus
which congenital disorder is characterized by an increased CSF content in the brain ventricles, leading to pressure on the nervous tissue?
cerebral hypoplasia
what is the medical term for the congenital disorder causing poor brain development?
the congenital disorder of no brain develpment
what is cerebral aplasia?
the congenital disorder where the skull does not close completely, so part of the brain is exposed
what is cranioschisis?
a congenital disorder where there is an abnormal sac of fluid, brain tissue, and meninges extending through a defect in the skull
a meningoencephalocele is....
cerebellar hypoplasia
what is the name for poor development of the cerebellum?
1 or more vertebrae do not form their arch normally during development, so the spinal cord is exposed and more susceptible to injury
what is spina bifida?
spina bifida
what congenital disorder does this baby have?

severe forms of spina bifida where the entire spinal vertebrae are not closed due to failure of the neural tube to close, leaving the entire spinal cord exposed
what is rachischisis/myeloschisis?
spina bifida (rachischisis and myeloschisis are severe forms)
what is the congenital disorder where vertebrae do not close correctly, leaving the spinal cord exposed?
the development of a cyst/cavity within the spinal cord
what is syringomyelia?
english bulldogs
spina bifida is common in what breed of dog?
king charles spaniels
syringomyelia is a common congenital disorder in what breed?
a dilation of the central canal of the spinal cord by CSF
what is hydromyelia?
syringomyelia
what is the congenital disorder where there is a formation of a cyst/cavity within the spinal cord?