DNA Replication
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8 Terms
What is “unwinding” the DNA and what number step is it?
Helicase “unzips” the helix and breaks hydrogen bonds at a replication fork, and it is step 1.
What is separating the DNA and what number step is it?
The two strands are held apart from each other and it is step 2.
What does primer do and what number step is it?
Primase adds a “signal” to indicate where to start replication, and it is step 3.
What happens when adding bases, and what step is it?
DNA Polymerase moves 5’ to 3’ adding complementary bases to the strands
Leading vs Lagging strand (4)
What is proofreading and what step is it?
DNA Polymerase “spell checks” as it adds bases, and it is step 5
Describe binding fragments, and what step is it?
Ligase bonds the Okazaki fragments of the lagging strand, and it is step 6
Does the lagging strand synthesize in a continuous or discontinuous fashion?
Discontinuous
How conservative is the process of DNA replication?
Semi-conservative
