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Flashcards about the Nervous System
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Dendrites
Branches that receive incoming signals
Soma (Cell Body)
Contains the nucleus and organelles
Axon Hillock
Where the action potential begins
Axon
Long fiber that carries electrical signal away from the soma
Axon Terminals
Ends of the neuron where neurotransmitters are released
Resting Membrane Potential
Electrical charge across the membrane when not active (about -70 mV)
Sodium-Potassium ATPase
Pump that moves 3 Na out and 2 K in to maintain resting potential
Ion Gradients (Na, K)
More Na outside, more K inside; drives electrical activity
Graded Potentials
Small, local changes in membrane voltage
Depolarization
Membrane potential becomes more positive
Hyperpolarization
Membrane potential becomes more negative
Repolarization
Return to resting potential after depolarization
Action Potential
Rapid electrical signal sent down an axon
Threshold
Minimum voltage required to trigger an action potential
All-or-None Principle
Action potential fires fully or not at all
Refractory Period
Time when neuron can't or is less likely to fire again
Leak Channels
Always open, allow passive ion movement
Chemically Gated Channels
Open when neurotransmitter binds
Voltage-Gated Channels
Open when membrane voltage reaches a threshold
Mechanically Gated Channels
Open when physically deformed
Electrical Synapse
Direct connection between cells via gap junctions
Chemical Synapse
Signal sent using neurotransmitters across a synaptic cleft
Synaptic Delay
Brief pause as neurotransmitter crosses the synapse
Synaptic Fatigue
Depletion of neurotransmitter after overuse
Excitatory Neurotransmitter
Increases chance of action potential (e.g., glutamate)
Inhibitory Neurotransmitter
Decreases chance of action potential (e.g., GABA)
Direct Effect
Neurotransmitter directly opens ion channels
Indirect Effect via G Protein
Neurotransmitter triggers second messenger pathway
EPSP
Excitatory postsynaptic potential; small depolarization
IPSP
Inhibitory postsynaptic potential; small hyperpolarization
Temporal Summation
Repeated signals from same source over time
Spatial Summation
Simultaneous signals from multiple sources
Presynaptic Inhibition
Reduces neurotransmitter release
Presynaptic Facilitation
Increases neurotransmitter release