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at what pHs are amino acids negatively, neutral and positively charged
pH > 9 = negatively charged
pH 7 = neutral
pH < 2 = positively charged
occurs because AA are ionisable due to carboxyl and amide groups
acidic amino acids have a negative charge at pH 7
basic amino acids have a positive charged at pH 7
what feature of a protein does charge determine
the shape
describe what a peptide bond is
formed via a condensation reaction between a carboxyl and amide group of adjacent AA
enzyme peptidyl transferase (found in ribosome) catalyses formation during translation
properties of peptide bonds (5)
rigid
planar
covalent
stable
physiologically only broken by proteases
how many peptide bonds does the average protein have
300
varies greatly