Nurs 3366 - Kidney Purpose and Function

What is the function of the Kidney?

decide the concentration of urine

• 95% urine and 5% waste(urea nitrogen and creatinine)

What is the function of the Glomerulus?

blood enters & gets filtered at the glomerular membrane

• Glomerular Filtration Rate(GFR) - 125ml/min

What occurs when there is decreased GFR?

increase of water and waste in the body

How can you diagnose decreased GFR?

oliguria - low urine output less than 30ml/hr

What is Tubular reabsorption?

what the body “absorbs” back into the blood

What is Tubular secretion?

what the body is getting rid off from blood to the urine

What are the substances that help the Glomeruli and Tubules?

angiotensin II, aldosterone, ADH, natriuretic peptides

How can you know if the Kidneys are not working properly?

• Low Glomerular Filtration Rate (GFR)

• High serum creatinine & urea nitrogen

• Low urine creatinine & urea nitrogen.

How do the Kidney’s deal with a fluid deficit?

renin secreted by the JGA (juxtaglomerular apparatus) secretes Angiotensin II

• vasoconstriction

• secretion of aldosterone causes the retention ofNa+ into the blood, followed by H2O

How do the Kidney’s deal with a fluid overload?

BNP & ANP secreted by heart & go to renal tubules

• stimulated to excrete more water into the urine, void dilute urine

What are the Metabolic functions the Kidney’s control?

• acid/base balance - making and regulating HCO3 and excrete H+

• regulate calcium absorption - by activating Vitamin D

• make erythropoietin - helps with RBC birth & growth