Table 5-4

membrane attack complex

membrane attack complex

involved in lysis of bacterial/cell membranes

C3b, C4b

complements involved in covalent opsonization

C3a and C5a

complements that induce inflammation and chemotaxis by anaphylatoxins

C3b and C4b, C3 receptor

complements and receptor that augment antibody response

C3b and C4b

complements that enhance immunologic memory, receptor on dendritic cells

MBL, C1q, C3b, C4b, and C5a

complements that enhance antigen presentation

C3, C3a, C3b, C5a

complements that have potential effects on T-cells

C1, C2, C3, and C4

complements involved in clearance of immune complexes from tissues in contraction phase

C1q, C3, and C4

complements involved in clearance of apoptotic cells in contraction phase

CD46

induces regulatory T-cells in contraction phase