Microbiology - Chapter 20

[ch 20] Adaptive or specific immunity includes _.

• cell-mediated immunity
• innate immunity
• humoral immunity
• cell-mediated immunity and humoral immunity

cell-mediated immunity and humoral immunity

[ch 20] Effector T cells can be categorized as memory cells and CD4+ cells

True or False

False

[ch 20] _ are chemical messengers used by T cells to communicate with each other to promote clonal expansion and proliferation.

• Neurotransmitters
• Cytokines
• Steroids
• Hormones

Cytokines

[ch 20] A dendritic cell is expressing MHC class I + antigen derived from the proteasome on its surface. It is likely going to activate CD4 T cells.

True or False

False

[ch 20] Effector CD4 T cells directly kill antigen.

True or False

False

[ch 20] Each B cell is genetically coded to make a/an:

• single T cell receptor
• single B cell receptor
• CD4+ receptor
• CD8+ receptor

single B cell receptor

[ch 20] Plasma B cells secrete antibodies

True or False

True

[ch 20] Antibodies can:

• neutralize antigens
• activate complement
• stimulate opsonization and agglutination
• stimulate antibody dependent cellular cytotoxicity
• all of these choices

all of these choices

[ch 20] Antibodies directly kill their antigen.

True or False

False

[ch 20] Effector helper T cells are to naive CD4 T cells like _ are to naive B cells.

• Memory B cells
• Plasma cells
• CD4 T cells
• CD8 T cells

Plasma cells

[ch 20] You have extracted secreted antibody from the bloodstream. You want to determine whether this antibody is capable of inducing opsonization. In examining the protein structure, which part of the antibody would you study to answer your question?

• The antigen binding site
• The heavy chain
• The light chain and the heavy chain
• The light chain
• All of these parts

The heavy chain

[ch 20] These cells are responsible for antibody mediated immunity.

• T cells
• B cells
• Macrophages
• Erythrocytes
• Platelets

B cells

[ch 20] B cells differentiate into _ which produce antibodies.

• monocytes
• macrophages
• T cells
• plasma cells
• eosinophils

plasma cells

[ch 20] T cell costimulation is commonly needed to activate B cells during antibody mediated immunity.

True or False

True

[ch 20] Which of the following is NOT characteristic of the primary immune response?

• The response only involves T cells.
• Only a few cells can initially recognize the specific antigen.
• The response is slow and may take several weeks to develop.
• Clonal expansion of B cells and T cells occur after antigen exposure.
• Memory cells produced during this response can last for years.

The response only involves T cells.

[ch 20] The peptide antigen presented to T cells is bound to major histocompatibility (MHC) molecules expressed on the surface of APCs.

True or False

True

[ch 20] Which of these is the most prominent class of antibody present in serum?

• IgA
• IgD
• IgE
• IgG
• IgM

IgG

[ch 20] Which of the following may activate a naive CD4 T cell?

• A neutrophil expressing MHC class I + antigen
• A dendritic cell expressing MHC class I + antigen
• A dendritic cell expressing MHC class II + antigen
• A macrophage expressing MHC class I + antigen

A dendritic cell expressing MHC class II + antigen

[ch 20] Memory T cells utilize a similar T cell receptor to recognize and become activated by the same antigen should an infection occur again.

True or False

True

[ch 20] What is true of the antigen binding site?

• The antigen binding site is the same on all the receptors on a single naive B cell.
• The antigen binding site contains a heavy chain and a light chain.
• Each antibody has two antigen binding sites.
• All of these statements are true.

All of these statements are true.