Ligand gated ion channels
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6 Terms
Ionotropic receptors examples
Nicotinic acetylcholine receptor
GABA receptor
Metabotropic receptor example
Muscarinic acetylcholine receptor
Nicotinic acetylcholine receptor
Mediates effects of acetylcholine (ACh) on muscles etc
Binding of ACh opens channel and allows Na+ entry
Binds nicotin
Inward Na+ current triggers response (calcium may also enter through this channel)
GABA receptor
Selective for Cl- ions
Naturally activated by GABA = CNS neurotransmitter
Inhibitory receptors
Activated by benzodiazepines/alcohol
Muscarinic acetylcholine receptor
Activated by acetylcholine
Metabotropic = indirectly linked with ion channels on the plasma membrane through signal transduction pathway
Generally G protein mediated
Note 
Flashcards (41)