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Excitability
Ability to receive and respond to stimuli
Contractibility
ability to shorten and thicken
Extensibility
ability to stretch
Elasticity
ability to return to its original shape after contraction or extension
Skeletal muscle
Attached to bone
Skeletal muscle
Move the whole body
Skeletal muscle
Muscle type that contains Multiple peripheral nuclei
Skeletal muscle
Control is voluntary in this type
Skeletal, cardiac
Muscle types that Have striations
Skeletal muscle
Cylindrical cell shape
Smooth muscle
Exists on hollow organs, glands, and blood vessels
Smooth muscle
Function is the compression of tubes and ducts
Smooth muscle
Muscle type that contains single, central nuclei
Smooth, cardiac
Control is involuntary in these two types
Smooth muscle
Has no striations
Smooth muscle
Spindle-shaped cells
Cardiac muscle
Type of muscle in the heart
Cardiac muscle
Function of this muscle type is heart contraction to propel blood
Cardiac muscle
Muscle type with central and single nuclei
Cardiac muscle
Muscle type with branched-shaped cells
Skeletal
___________________ muscles are responsible for all locomotion
Smooth
___________________ muscle helps maintain blood pressure, and squeezes or propels substances (i.e., food, feces)
through organs
Cardiac
_______________muscle is responsible for coursing the blood through the body
Skeletal, smooth
___________ and ____________ muscle cells are elongated and are called muscle fibers
Cardiac
_______________muscle is responsible for coursing the blood through the body
Skeletal, smooth
________________ and _____________ muscle cells are elongated and are called muscle fibers
Actin, myosin
Muscle contraction depends on these two kinds of myofilaments
Sarcolemma
Muscle contraction depends on two kinds of myofilaments
Sarcoplasm
Cytoplasm of a muscle cell
Myo, mys, sarco
______, ________ and _______ are prefixes that all refer to muscle.
650
Number of muscles attached to the skeleton
Pairs
Muscles work in ___________: one muscle moves the bone in one direction and the other moves it back again.
Joints
Muscle movement bends the skeleton at moveable ___________.
Tendons
Muscles are anchored firmly to bone by ___________.
Tendons
made of dense fibrous connective tissue shaped like
heavy cords.
Origin
Attachment to the more stationary bone by tendon closest to the body or muscle head or proximal is the ______________.
Insertion
attachment to the more moveable bone by tendon at the distal end is the_______________.
Injured
Though very strong and secure to muscle, tendons may be _____________.
Pull of contraction
The force producing the bending is always a ______ ___ _____________.
Muscle contractions
can be short, single contractions or longer ones.
Contracts, stretches
As one group of muscles _______________, the other ___________ and then they reverse actions
Muscle contractions
_________ ___________can be short, single contractions or longer ones.
Joints, bone
Muscles span ______ and are attached to ________ in at least two places
Movable, immovable
When muscles contract the __________ bone, the muscle's insertion moves toward the _________ bone -
the muscle's origin
Directly
When muscles attach _________ the epimysium of the muscle is fused to the periosteum of a bone
Indirectly
When muscles attach __________ the CT wrappings extend beyond the muscle as a tendon or aponeurosis
Nerve, artery, veins
Each muscle is served by one _________, an ________, and one or more __________.
Contraction
Each skeletal muscle fiber is supplied with a nerve ending that controls ______________.
Nerve ending
Each skeletal muscle fiber is supplied with a _______ __________ that controls contraction.
Oxygen, nutrients
Contracting fibers require continuous delivery of ________ and ___________ via arteries.
Veins
Wastes must be removed via ________.
Wastes
_________ must be removed via veins
Origin, insertion
Each muscle has thousands of muscle fibers in a bundle running from _______ to _________ bound together by connective tissue through which run blood vessels and nerves.
Muscle fibers
Each muscle has thousands of ______ _________ in a bundle running from origin to insertion bound together by connective tissue through which run blood vessels and nerves.
Blood vessels, nerves
Each muscle has thousands of muscle fibers in a bundle running from origin to insertion bound together by connective tissue through which run ________ _________ and _______.
Nuclei
Each muscle fiber contains many ________.
Endoplasmic reticulum, sarcoplasmic reticulum
Each muscle fiber contains an extensive __________ ____________ or _________ _____________.
Myofibrils
Each muscle fiber contains many thick and thin ____________ running lengthwise the entire length of the fiber.
Mitochondria
Each muscle fiber contains many ______________ for energy.
Epimysium, perimysium, endomysium
The three connective tissue wrappings are:
Epimysium
an overcoat of dense regular CT that surrounds the entire muscle
Perimysium
fibrous CT that surrounds groups of muscle fibers called fascicles
Endomysium
fine sheath of CT composed of reticular fibers surrounding each muscle
Sarcomere
The basic functional unit of the muscle fiber is the
myosin, actin
The sarcomere consists of thick filaments with __________ (protein) molecules and thin filaments with _________ (protein) molecules plus smaller amounts of troponin and tropomysin.
A, I
When viewed under the microscope, sarcomeres appear as striations of dark ___ bands and light ___ bands.
A, H
The ___ bands are bisected by the ___ zone with the M line or band running through the center of this zone.
I, Z
___ bands are bisected by the ___ disk or line.
Sarcomere
A _______________ consists of the array of thick and thin filaments between two Z disks.
Myosin head
In the thick filaments, myosin molecules contain a globular subunit, the __________ _______.
Myosin head
Has binding sites for the actin molecules of thin filaments and ATP.
Actin
Activating the muscle fiber causes the myosin
heads to bind to _______ molecules pulling the short filament a short distance past the thick filaments.
ATP energy
The linkages break and reform using ______ _________ further along the thick filaments.
shortening, thickening, folding
The linkages break and reform (using ATP energy) further along the thick filaments. Thus the thin filaments are pulled past the thick filaments in a ratchet-like action. No _________, __________ or _______ of individual filaments occurs.
Contracts, decrease
As the muscle _________, the width of the I bands and H zones ________ causing the Z disks to come closer together, but there is no change in the width of the A band because the thick filaments do not move.
Separate, apart
As the muscle relaxes or stretches, the width of the I bands ________ as the thin filaments move _____ but the thick filaments still do not move.
Motor unit
A _____ _____ is a motor neuron and all the muscle fibers it supplies.
Muscle fibers
The number of ______ _______ per motor unit can vary from four to several hundred.
Small
Muscles that control fine movements (fingers, eyes) have _______ motor units.
Large
Large weight-bearing muscles (thighs, hips) have _______ motor units.
Muscle fibers
________ ________ from a motor unit are spread throughout the muscle; therefore, contraction of a
single motor unit causes weak contraction of the entire muscle.
Cross bridge attachment
myosin cross bridge attaches to actin filament.
Working (power) stroke
myosin head pivots and pulls actin filament toward M line.
Cross bridge detachment
ATP attaches to myosin head and the cross bridge detaches
Cocking of myosin head
energy from hydrolysis of ATP cocks the myosin head into the high energy state.
Nerve ending
In order to contract, a skeletal muscle must Be stimulated by a _______ ________.
Sarcolemma
In order to contract, a skeletal muscle must Propagate an electrical current, or action potential, along its _____________.
Intracellular
In order to contract, a skeletal muscle must Have a rise in __________ Ca2+ levels, the final trigger for contraction.
Excitation-contraction coupling
Linking the electrical signal to the contraction is ____________-____________ _________.
somatic nervous system
Skeletal muscles are stimulated by motor neurons of the ____________ _________ ___________.
Axons
_________ of neurons travel in nerves to muscle cells.
Motor neurons
Axons of _______ _________ branch profusely as they enter muscles.
Neuromuscular junction
Each axonal branch forms a _____________ ________ with a single muscle fiber.
Muscle fatigue
Term for when the muscle is in a state of physiological inability to contract.
Production, use
Muscle fatigue occurs when ATP __________ fails to keep pace with ATP _____.
ATP
Muscle fatigue occurs when there is a relative deficit of _____, causing contractures.
Lactic acid
Muscle fatigue occurs when ________ ______ accumulates in the muscle.
Ionic
Muscle fatigue occurs when _______ imbalances are present.
Chemistry
Vigorous exercise causes dramatic changes in muscle ___________.
Oxygen
For a muscle to return to a resting state, ________ reserves must be replenished