Neuroleptic Malignant Syndrome (NMS) Overview

Flashcards covering the key concepts and symptoms of Neuroleptic Malignant Syndrome (NMS) for study and review.

NMS is a potentially fatal complication of certain __ medications.

anti-psychotic

Manifestations of NMS include hyperpyrexia up to __.

107°F

Symptoms of NMS can occur within to or even years later during drug therapy.

24 hours; two weeks

Certain neuroleptic drugs can cause an idiosyncratic reaction leading to NMS, including and .

Thioridazine; Haloperidol

The pathophysiology of NMS involves an imbalance of many neurotransmitters affecting the central __ system.

dopamine

This anti-psychotic drug class can lead to muscle rigidity as seen in __ disease.

Parkinson's

To treat NMS, it is crucial to identify early and __ the drug immediately.

stop

After recovery from NMS, a __ may be slowly reintroduced to the patient.

low-potency neuroleptic

High-potency neuroleptic use increases the risk of developing __.

NMS

Other potential risk factors for NMS include dehydration, __, and malnutrition.

agitation