Revision Questions - Patterns of Disease in the Lung 1+2: Inflammation & Neoplasia

M.9, W.3, L.1+2

Describe the distribution of lesions you would expect to see in lungs with bronchopneumonia.

Cranioventral lung consolidation

Name the classic histologic lesion associated with chronic enzootic pneumonia?

BALT Hyperplasia (cuffing)

Name a virus in sheep that causes interstitial pneumonia and name the condition.

• Ovine Lentivirus; Maedi-Visna Virus

• Ovine Progressive Pneumonia (OPP)

what gross appearance of the lung at post mortem examination is suggestive of interstitial pneumonia?

enlarged lung, rib imprints, does not collapse

name the plasma protein that leaks from vessels during acute inflammation to polymerize to form soft yellow adhesions

Fibrinogen

Name the soft adhesions that are seen in acute pleuritis/pleurisy

Fibrin / Fibrinous

Name the bovine granulomatous pneumonia that is notifiable, name the causal agent

Tuberculosis (T.B), Mycobacterium Bovis

Patterns of Lung Disease 2: Inflammation and Neoplasia

Patterns of Disease in Lung 2: Inflammation and Neoplasia

List 3 causes of granulomatous inflammation.

mycobacteria, fungus, foreign body (FB)

Name the predominant cell type in granulomatous infection

macrophage

Suggest 2 common lesions which predispose cattle to developing embolic pneumonia

endocarditis, hepatic abscess

explain lung digit syndrome in cats

cats present with lesions affecting their toes (digits), on biopsy there is an epithelial population which is recognized as pulmonary in origin

briefly explain the important differences between a primary and a secondary neoplasm

primary: could be benign or malignant; is the in the site it developed e.g. lung

secondary: has already metastasized when found; is malignant

name at least 2 neoplasms that commonly metastasize to the lungs

Hemangiosarcoma, Osteosarcoma, Mammary carcinoma