Exam 2 Excipient List

SNAC

Penetration Enhancer

Citric acid monohydrate

Buffer

Dibasic sodium phosphate dihydrate

Buffer

Mannitol

For Isotonicity, Humectant (retain moisture)

Sodium Chloride

For Isotonicity 

Sodium phosphate dibasic heptahydrate

Used as a buffer to maintain a stable pH

Hydrochloric acid solution & Sodium hydroxide solution

pH adjusters

Lantus Excipients:

Zinc: Conformational integrity

m-cresol: Preservative

Glycerol: Solvent

Mineral Oil

Levigating agent

Polysorbate 80

Surfactant and emulsifier; attracts and holds water

Xanthan Gum

Thickening agent

Benzododecinium bromide 0.012%, Benzalkonium chloride

Preservative

Monobasic and dibasic sodium phosphate

Buffer

Corn and potato starch, clays

Disintegrants

Silica

Glidant

Sodium benzoate

Preservative

Tablet Binders

Starch, gelatin, sugars, acacia, carboxymethylcellulose, methylcellulose

Tablet diluents (fillers)

Dicalcium phosphate, Calcium Sulfate, Lactose, Cellulose

Chemical Drug Absorption Enhancers:

DMSO, Dimethylacetamide, Dimethylformamide

Boric Acid

Tonicity agent

Ciprodex Excipients

Acetic acid and sodium acetate: Buffer

Edetate disodium: Preservative

Hydroxyethyl cellulose (HEC): Forms gel

Sodium Chloride: For isotonicity

Tylopaxol: Reduces viscosity, helps remove mucous and lipids from the area