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Primary functions of muscles
Move the skeleton, maintain posture and body position, support soft tissues, maintain body temperature, and guard entrances and exits
Move the skeleton
Muscles move bones and provide facial expressions
Maintain Posture
The ability to support the body against gravity
Maintain Body Position
Muscles, tendons, and ligaments help to stabilize poorly articulating joints
Maintain Body Temperature
Mitochondria makes ATP from glucose and oxygen; skeletal muscles use ATP for contractions and create heat as a by-product
How is the excess heat removed?
Blood vessels take heat away during circulation
Support soft tissues
Muscles support the weight of our visceral organs (in the abdominal wall and pelvic cavity floor) and shield our internal tissues from injury
Guard entrances and exits
Encircle openings of the digestive and urinary tracts. Gives us voluntary control over swallowing, defecating, and urinating
Epimysium
the connective tissue (collagen fibers) that covers the outside of the entire muscle. Separates muscles from surrounding tissues and organs
Perimysium
Divides the skeletal muscles into compartments. Wraps around a fascicle, contains fibers, nerves and blood vessels
Fascicle
Several muscle fibers bundled together
Endomysium
Repair damaged muscle tissue. Individual muscle cells (myofibril) in the fascicle are wrapped by this tissue. Contain capillaries that supply blood to the muscle fibers and neurons
Endomysium and Perimysium come together at the end of each muscle to form
Tendons (connect muscle to bone)
Sarcolemma
Flesh hulk, the plasma membrane of a muscle cell
Sacroplasm
Cytoplasm of the muscle cell
Transverse tubules/ t-tubules
Extensions of the sarcolemma that extend into the cell and carry nervous signals
Terminal Cisterna
Endoplasmic reticulum of the muscle that store calcium
Tubules extend into the cell and connect with portions of the sarcoplasmic reticulum. Nervous signals carried by t-tubules cause
Calcium to be released from the SR
Myofibril
Long organelles found inside the muscle cell. Contractile units that shorten the muscle during contraction. Banding pattern (striations)
Sarcomere
Unit of the myofibril that runs from one z line to the next z line
A band (Dark)
Part of the sarcomere that contains all of the thick filaments and only a portion of the thin filaments
I band (light)
Part of the sarcomere that contains the z line and only thin filaments
Sliding filament theory I band
It shortens due to thick filaments invading
Actin
Thin filaments. Troponin and tropomyosin anchored here
Myosin
Thick filaments. It’s heads attach to an active site on thin filaments during muscle contraction
H zone
Within the A band, only thick filaments
Sliding Filament Theory H zone
During muscle contraction it decreases (eventually disappears) due to the thin filaments invading
Z line (disc)
Zig-zag shaped line/ membrane where thick filaments are attached
Sliding Filament Theory Z line
Slides closer together (shortens) due to the myosin heads attaching to the thin filaments and pulling them in
Microfilaments
Long proteins made primarily of actin or myosin
Tropomyosin
These proteins coil over actin to prevent myosin heads from attaching to the active sites on actin
Troponin
Protein connected to tropomyosin. Calcium ions bind to it and allow tropomyosin to move and expose the active sites to allow myosin heads to attach to actin
Sarcoplasmic Reticulum
Wraps around the myofibril and releases calcium ions into the sarcoplasm to begin muscle contractions
This area causes both contraction and relaxation
Motor unit
The motor neuron and all the skeletal muscle cells it stimulates
Motor neuron (nerve cell)
Stimulates skeletal muscles
Neuromuscular junction
Where individual axon terminals stimulate one muscle cell. Nerve cells nearly contact the sarcolemma here
Synaptic cleft of the neuromuscular junction
The gap between the sarcolemma of the muscle cell and the axon terminals (synaptic knobs) of the nerve cell
Neurotransmitter released during contraction
Acetylcholine
After calcium ions diffuse into the sarcomere and muscle contraction occurs, the SR reabsorbs calcium causing:
Muscle relaxation
Sliding filament theory A band
Stays the same
Sliding filament theory sarcomere length
shortens or decreases