science
an organized way of gathering and analyzing evidence about the natural world
scientific method
the heart of science; 5 steps: observing and asking questions, making inferences and forming hypotheses , conducting controlled experiments, collecting and analyzing data, drawing conclusions
hypothesis
a scientific explanation for a set of observations that can be tested in ways that support or reject it; when enough experimental data support a hypothesis, the hypothesis becomes a theory
seven characteristics of living things
all living things are made of cells
obtain and use materials and energy
grow, develop, and can reproduce
maintain a stable internal environment (homeostasis)
universal genetic code (DNA/RNA)
respond to the environment
evolve as a group (smallest group that can evolve is a population)
population
a group of the same species living in the same area
three subatomic particles
protons (+), neutrons (0), electrons (-)
atomic number
the amount of protons in the nucleus
atomic mass
the weighted average of an elements isotopes
mass number
rounded atomic mass; protons + neutrons
isotopes
atoms with the same amount of protons but different amount of neutrons
ionic compounds
metal + nonmetal, electrons are TRANSFERRED (NaCl)
covalent compounds
nonmetal + nonmetal, electrons are SHARED (H2O)
valance electrons
electrons in the outermost shell
covalent bonds
occurs when valance electrons are SHARED by two atoms
nonpolar covalent bonds
electrons are shared EQUALLY between two atoms
electronegativity
a tendency to attract electrons of a covalent bond
polar covalent bonds
one atom has greater electronegativity than the other, results in an UNEQUAL sharing of the electrons
Ionic bonds
bonds where two atoms attract valance electrons so unequally that the more electronegative atom steals the electron away from the less electronegative atom; an ion is the resulting charged atom or molecule
cation
positive, metals, loses electrons (-), first in an ionic compound
anions
negative, nonmetals, gains electrons (+), second in an ionic compound
hydrogen bonds
relatively weak bonds that from between the partial positively charged hydrogen atom of one molecule and the strongly electronegative oxygen or nitrogen of another molecule; the key to all properties of water and what makes water so unique
chemical reaction
shows the reactants which are the starting materials, an arrow to indicate their conversion into the products, the ending materials
cohesion
an attraction between molecules of the same substance
adhesion
an attraction between molecules of different substances
why does ice float?
as water freezes, each molecule forms stable hydrogen bonds with its neighbors, holding them at “arms length” and creating a 3D crystal. ice crystals have fewer molecules than liquid water, therefore ice is less dense and floats on top of liquid water
solution
a liquid consisting of a uniform mixture of two or more substances
solvent
the dissolving agent; water is the solvent of life
solute
the substance that is dissolved
aqueous solution
a solution in which water is the solvent, water’s versatility as a solvent results from the polarity of its molecules
pH scale
measures the concentration pf hydrogen ions in a solution, the scale ranges from 0-14, pure water has a pH of 7
acidic solutions
have pH values below 7
basic or alkaline solutions
have pH values above 7
organic chemistry
the study of compounds with bonds between carbon atoms; CHONP
carbohydrates
monomers: monosaccharides, examples: glucose, fructose, cellulose, chitin, starch, functions: short term energy storage
proteins
monomers: amino acids, examples: enzymes, hormones, functions: structural support cell signaling and communication
lipids
monomers: triglycerides, examples: fats, oils, waxes, phospholipids, functions: long term insulation, membrane lipids
nucleic acids
monomers: nucleotides, examples: DNA, RNA, functions: store and transmit genetic information
timeline of cell discoveries
1665- Hooke discovers and names cells in thin slices of cork, 1676- Van Leeuwenhoek discovers protozoa by looking at pond water; first to see living cells under a microscope, 1831- Brown discovers and names the nucleus of the cell, 1838-39- Schleiden (plant) and Schwann (animal) theorize that all living things are made of cells, 1855- Virchow theorized that new cells are produced from existing cells
why are cells small?
as the radius of a cell increases, its surface area increases as the square of its radius, but its volume increases as the cube of its radius (much more rapidly). therefore, as a cell increases in size, its surface area-to-volume ratio decreases
prokaryotic cells
the microorganisms placed in domains Bacteria and Archaea consist of prokaryotic cells (prokaryotes); cells that do not have a nucleus but instead a nucleoid which is a region where the cell’s DNA is located (not enclosed by a membrane); prokaryotic cells are structurally simpler than eukaryotic cells
eukaryotic cells
all other forms of life are placed in domain Eukarya (eukaryotes); these cells have a membrane enclosed nucleus, which houses most of their DNA, and many membrane bound organelles that perform specific functions
cell theory
all things are made of cells
cell are the basic unit of structure and function in living things
new cells are produced from existing cells
organelles
small structures inside a cell that are surrounded by a membrane and have a specific function.
nucleus
contains the cell’s genetic instructions encoded in DNA; serves as as the control center for cell metabolism and reproduction (ribosome factory)
ribosomes
if the nucleus is the command center, then ribosomes are the machines that carry out those commands. ribosomes are the cellular components that use instructions from the nucleus written in mRNA, to build proteins; sites of protein synthesis
endoplasmic reticulum (ER)
the ER is an extensive network of flattened sacs and tubules, it is a prime example of the direct and indirect interrelatedness of parts of the endomembrane system; serves as a pathway for the transport of materials throughout the cell, also associated with synthesis and storage
smooth ER
outer surface lacks ribosomes; functions in a variety of metabolic processes; stores calcium ions
rough ER
has bound ribosomes that stud the outer surface of the membrane ,appears rough,; many types of cell secrete proteins produced by ribosomes attached to rough ER, the rough ER is also involved with the production, folding, quality control and dispatch of some proteins
Golgi apparatus
modifies, sorts, and ships cell products; the Golgi serves as a molecular warehouse and processing station for products manufactured by the ER
lysosomes
a membrane-enclosed sac of digestive enzymes, lysosomes have several types of digestive functions; also serve as recycling centers
vacuoles
large vesicles that have a variety of functions; fluid filled organelles enclosed by a membrane; contains stored food or wastes
mitochondria
the powerhouse of the cell; organelles that carry out cellular respiration in nearly all eukaryotic cells; mitochondria use O2 and release CO2 in transforming the chemical energy of foods to a form (ATP) that can be used for cellular work
chloroplasts
site of photosynthesis; carries out complex multi-step processes; enclosed by an inner and outer membrane separated by a thin internal membrane space
cilia
hairlike structures with the capacity for movement
flagella
a long, hairlike structure used for movement; propel a cell through its liquid environment
cell wall
gives the cell its shape and provides protection; not found in animal cells only plant
cell membrane
AKA plasma membrane, regulates what comes in and out of the cell; made up of the phospholipid bilayer
hydrophilic
water attracting; the phospholipid head is hydrophilic
hydrophobic
water repelling; the two phospholipid tails are hydrophobic
carbohydrate chains
cells are able to recognize various molecules and other types of cells with the carbohydrate chains
integral proteins
helps transport materials (such as glucose) across the cell membrane
peripheral proteins
involved in cell to cell recognition
cholesterol
helps maintain the flexibility of the membrane
passive transport
does not require energy; an example of passive transport is diffusion, the process by which particles move from an area of high concentration to an area of lower concentration
active transport
the movement of materials against a concentration difference; requires energy
osmosis
the facilitated diffusion of water through a selectively permeable membrane
facilitated diffusion
the process by which molecules that cannot directly diffuse across the membrane pass through special protein channels
hypertonic solution
(water leaves the cell) there is more M OUTSIDE the cell; plant cells: plasmolysis occurs, the plasma membrane pulls away from the cell wall,
animal cells: shrinks (losing water)
isotonic solution
(water enters and leaves the cell equally)
plant cells: start to wilt
animal cells: normal
hypotonic solution
(water enters the cell) more M INSIDE the cell;
plant cell: normal (has turgor pressure)
animal cell: can burst, will swell (lysis)
molarity
used to express the concentration of a solution, how concentrated or diluted; moles of a solute over liters of a solution
M
molar
ATP
adenosine-triphosphate, made of of adenine, ribose a 5 carbon sugar, and 3 phosphate groups; ATP is the source of energy for use and storage in cells
cell cycle
a series of events (including mitosis) that take place in a cell as it grows and divides (end results= two identical daughter cells)
G1 phase
cell grows larger and makes proteins and organelles needed for DNA synthesis
S phase
DNA synthesis occurs, where DNA is copied
G2 phase
organelles and proteins necessary for cell division grow in preparation for mitosis
M phase
nuclear division (mitosis) occurs, followed by cytoplasmic division (cytokinesis)
mitosis
prophase, anaphase, metaphase, telophase; NOT cytokinesis; PMAT
interphase
periods of growth between cell divisions (G1,S,G2)
prophase
DNA condenses from chromatin
metaphase
chromosomes line up on the metaphase plate
anaphase
sister chromatids move to opposite ends of the cell
telophase
nuclear membrane forms around chromosomes
cytokinesis
separation of the cytoplasm, results in two identical cells
photosynthesis
carbon dioxide + water --light→ glucose + oxygen
6CO2 + 6H2O --light→ C6H12O6 + 6O2
takes place in the chloroplast
stages of photosynthesis
light independent reactions(Calvin Cycle): do not require direct sunlight, take place outside the thylakoids, in the stroma; produce ADP and NADP+ and put it back into light dependent rxns
light dependent reactions: require direct sunlight, take place in the thylakoid membranes; produce ATP and NADPH
thylakoids
saclike chlorophyll-containing membranes
granum
thylakoids that are interconnected and arranged in stacks
stroma
the fluid portion of the chloroplast, outside of the thylakoids
autotrophs
organisms that make their own food/energy; go through photosynthesis
heterotrophs
organisms that cannot make their own food; dependent on autotrophs as an energy source
cellular respiration
6O2 + C6H12O6 → 6CO2 + 6H2O + energy
oxygen + glucose → carbon dioxide + water + energy
what is the relationship between photosynthesis and cellular respiration?
photosynthesis put backwards is cellular respiration and vise versa; photosynthesis removes carbon dioxide from the air, and cellular respiration puts it back
anaerobic
pathways of cellular respiration that do not use oxygen
aerobic
pathways of cellular respiration that require oxygen
glycolysis
glucose first enters a chemical pathway known as glycolysis, only about 10 percent of its energy is captured to produce ATP during this stage; occurs in the cytoplasm; enzymes split a molecule of glucose into two molecules of pyruvate, which releases energy that is transferred to ATP; 2 ATP molecules
Krebs (citric acid cycle)
energy stored in pyruvate is transferred to NADH and FADH2, and some 36 molecules ATP is produced with the help of glycolysis
oxidative phosphorylation
energy is harnessed through a series of protein complexes embedded in the inner-membrane of mitochondria (called the electron transport chain and ATP synthase) to create ATP
how does ATP drive cellular work; how cells transform energy and matter
the ATP molecule splits off one of its three phosphate groups, becoming ADP + a phosphate group