Granular Leukocytes
Neutrophil, Eosinophil, Basophil
Agranular Leukocytes
Lymphocyte, Monocyte
Neutrophil
Neutrophil
60-70%
Neutrophil
Phagocytosis. Destruction of bacteria with lysozyme, defensins, and strong oxidants, such as superoxide anion, hydrogen peroxide, and hypochlorite anion
Eosinophils
Eosinophils
2-4%
Eosinophils
Combat effects of histamine in allergic reactions, phagocytize antigen–antibody complexes, and destroy certain parasitic worms
Basophils
Basophils
0.5-1%
Basophils
Liberate heparin, histamine, and serotonin in allergic reactions that intensify overall inflammatory response.
Lymphocytes
Lymphocytes
20-25%
Lymphocytes
Mediate immune responses, including antigen–antibody reactions. B cells develop into plasmocytes, which secrete antibodies. T cells attack invading viruses, cancer cells, and transplanted tissue cells. Natural killer cells attack wide variety of infectious microbes and certain spontaneously arising tumor cells.
Monocytes
Monocytes
3-8%
Monocytes
Form platelet plug in hemostasis; release chemicals that promote vascular spasm and blood clotting.