Impacts of Bioinformatics

Massive Quantities of data

• _____ bases

• Human Genome: _________ = 200 HUGEs

• Macromolecular structures: _______

• 6×10^11

• 3×10^9

• <100,000

CONTRIBUTOR TO GLOBAL ECONOMY (4)

• Pharmaceutical industry and Drug discovery

• Agriculture

• Healthcare

• Environment

• analysis of data

• addresses biomedical challenges

• new diagnostics

• therapeutics

• understanding pathogenicity

• reclassification of diseases

Bioinformatics in Healthcare

• reduce the time and cost for developing drugs

• "drug-likeness" by genetic algorithms

• validation of new drugs

• provide information of target candidates

• understand pharmacokinetics

Bioinformatics in Drug Discovery

• personal identification and relatedness to other individuals

• analysis and comparisons of large numbers of biological samples

• DNA profiles

Bioinformatics in Forensic Analysis

• genetic understanding of plant performance at multiple levels of aggregation

• functional analysis of pathogen resistance of crops

• information on mutations, markers, maps, functional discoveries

Bioinformatics in Crop Improvement

• prevent introduction of known allergens

• identify protentially cross-reactive allegerns with pre-existing allergens

Bioinformatics in Food Analysis

ETHICAL ISSUES IN BIOINFORMATICS (4)

• USE OF GENETIC INFORMATION

• PSYCHOLOGICAL IMPACT

• RACISM

• ETHICAL, LEGAL AND SOCIAL ISSUES (ELSI) RESEARCH PROGRAM