Hyponatremia Drugs
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Last updated 1:23 AM on 10/22/25
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4 Terms
1
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Drug induced SIADH
SSRIs: citalopram, escitalopram, fluoxetine, paroxetine
SNRIs: desvenla, venla, duloxetine
carbamazepines
opiates
2
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Vasopressein Antagonists
demeclocycline
tolvaptan
conivaptan
3
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Demeclocycline
induces diabetes inispidus, risk of AKI and renal tubular damage
CI: kids, pregnancy d/t changes in tooth development
4
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Tolvaptan
V2 antagonist
indicated for hyper- and euvolemic hyponatremia due to HF, cirrhosis, or SIADH
AE: thirst, polyuria, constipation
BBW: hepatotoxicity
CYP3A4 and P-glycoprotein substrate = lots of DDIs
Note 
Flashcards (31)