Midterm OB/GYN ~ Sept 2025

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Chapter 41 - 52

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<p><strong><mark data-color="yellow" style="background-color: yellow; color: inherit;"><u>MC benign cyst in vagina</u></mark></strong></p>

MC benign cyst in vagina

Gartner Duct Cyst

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<p><strong><mark data-color="yellow" style="background-color: yellow; color: inherit;"><u>MC congenital abnormality in the female GI TRACT</u></mark></strong></p><ul><li><p>results in</p><ul><li><p>hydrometra</p></li><li><p>hematometra</p></li><li><p>pyometra</p></li></ul></li></ul><p></p>

MC congenital abnormality in the female GI TRACT

  • results in

    • hydrometra

    • hematometra

    • pyometra

Imperforated Hymen

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<p><strong><mark data-color="yellow" style="background-color: yellow; color: inherit;"><u>MC area of intraperitoneal fluid collection</u></mark></strong></p><p>can happen in anterior cul-de-sac</p>

MC area of intraperitoneal fluid collection

can happen in anterior cul-de-sac

Posterior Cul-de-sac

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Cervix normal measurement

2- 4 CM

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<p><strong><mark data-color="yellow" style="background-color: yellow; color: inherit;"><u>MC benign  cystic lesion </u></mark></strong></p><ul><li><p>caused by</p><ul><li><p>chronic cervitis</p></li><li><p>&lt;2 cm cysts</p></li></ul></li></ul><p></p>

MC benign cystic lesion

  • caused by

    • chronic cervitis

    • <2 cm cysts

Nabothian Cyst

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<ul><li><p>Irregular bleeding</p></li><li><p>benign</p></li><li><p>may be pedunculated</p></li><li><p>45 - 60 yrs (late middle ages) </p><p></p></li></ul><p></p>
  • Irregular bleeding

  • benign

  • may be pedunculated

  • 45 - 60 yrs (late middle ages)

Cervical Polyp

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<ul><li><p>caused by </p><ul><li><p>radiation</p></li><li><p>surgery</p></li><li><p>infection</p></li><li><p>menopause</p></li></ul></li><li><p>post meno - hydro/hemato/pyo metra</p></li><li><p>pre meno - inferility, cramps, irregular or no period</p></li></ul><p></p>
  • caused by

    • radiation

    • surgery

    • infection

    • menopause

  • post meno - hydro/hemato/pyo metra

  • pre meno - inferility, cramps, irregular or no period

Cervical stenosis

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<p><strong><mark data-color="yellow" style="background-color: yellow; color: inherit;"><u>Mc cervical malignancy</u></mark></strong></p><ul><li><p>vaginal discharge/bleeding</p></li></ul><p></p>

Mc cervical malignancy

  • vaginal discharge/bleeding

Cervical Carincoma (MC: squamous cell carcinoma)

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<ul><li><p>congenital anomaly</p></li><li><p>incomplete mullerian duct fusion</p></li></ul><p></p>
  • congenital anomaly

  • incomplete mullerian duct fusion

Bicornuate uterus

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<ul><li><p>2 uterus</p></li><li><p>2 cervix</p></li><li><p>Failure of mullerian duct fusion </p></li><li><p>congenital anomaly </p></li></ul><p></p>
  • 2 uterus

  • 2 cervix

  • Failure of mullerian duct fusion

  • congenital anomaly

Uterus Didelphys

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<p>MC uterine position </p>

MC uterine position

Anteverted

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<img src="https://knowt-user-attachments.s3.amazonaws.com/2820b195-ce11-4c2c-b764-abc309784354.png" data-width="100%" data-align="center"><p></p>

Anteflexed

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term image

Retroverted

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term image

Retroflexed

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<p><strong><mark data-color="yellow" style="background-color: yellow; color: inherit;"><u>MC uterine pelvic tumor</u></mark></strong></p><ul><li><p>&gt; 30 yrs</p></li><li><p>Black women</p></li><li><p><strong>estrogen-dependent</strong></p><ul><li><p>pelvic pain</p></li><li><p>pain</p></li><li><p>heavy or irregular bleeding</p></li></ul></li></ul><p></p>

MC uterine pelvic tumor

  • > 30 yrs

  • Black women

  • estrogen-dependent

    • pelvic pain

    • pain

    • heavy or irregular bleeding

Leiomyoma (Fibroid)

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<p>What kind of fibroid is this? </p><p>Has a stalk </p>

What kind of fibroid is this?

Has a stalk

Pedunculated Fibroid

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<ul><li><p>Heavy bleeding</p></li><li><p>pregnancy loss</p></li><li><p>Infertility</p></li><li><p>wha location is this?</p></li></ul><p></p>
  • Heavy bleeding

  • pregnancy loss

  • Infertility

  • wha location is this?

Intramural (within myometrium)

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<p>Fil in blank</p>

Fil in blank

Intramural Fibroid

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<p>Fill in blank</p>

Fill in blank

Submuosal Fibroid

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<ul><li><p>bleeding</p></li><li><p>ANEMIA</p></li><li><p>fertility issues </p></li></ul><p>what location is this</p>
  • bleeding

  • ANEMIA

  • fertility issues

what location is this

Submucosal (in endo)

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<p>Fill in blank </p>

Fill in blank

Subserousal Fibroid

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<ul><li><p>sometimes pedunculated (stalk)  </p></li></ul><p></p>
  • sometimes pedunculated (stalk)

Subserousal (outside)

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<p>Fill in blank</p>

Fill in blank

Intracavitary Fibroid

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<p>what location is this fibroid in ?</p><p></p>

what location is this fibroid in ?

Intracavitary

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term image

Fibroid location chart

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<ul><li><p>form of endometriosis<strong> (WITHIN MYOMETRIUM)</strong></p></li><li><p>benign, ectopic occurrence of endometrial tissue invasion</p></li><li><p>OLDER WOMEN</p></li><li><p>MULTIPARIOUS</p><ul><li><p>heavy, painful periods</p></li><li><p>tenderness</p></li><li><p>Hypermenorrhea (heavy bleeding)</p></li><li><p>metorrhea (irregular bleeding)</p></li></ul></li></ul><p></p>
  • form of endometriosis (WITHIN MYOMETRIUM)

  • benign, ectopic occurrence of endometrial tissue invasion

  • OLDER WOMEN

  • MULTIPARIOUS

    • heavy, painful periods

    • tenderness

    • Hypermenorrhea (heavy bleeding)

    • metorrhea (irregular bleeding)

Adenomyosis

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<p>MC cause of abnormal uterine bleeding in PRE and POST menopausal </p><ul><li><p>estrogen stimulation (PCOS, obesity)</p></li><li><p>pre meno &gt; 14mm</p></li><li><p>post meno &gt; 8 mm</p></li><li><p>precursor to cancer</p></li></ul><p></p>

MC cause of abnormal uterine bleeding in PRE and POST menopausal

  • estrogen stimulation (PCOS, obesity)

  • pre meno > 14mm

  • post meno > 8 mm

  • precursor to cancer

Endometrial Hyperplasia

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In menstrual phase, how thick is endo

2 -3 mm

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In proliferative phase, how thick is endo?

4 -6mm

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In periovulatory phase, how thick is endo?

6-8 mm

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In secretory phase, how thick is endo?

8-15 mm

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<ul><li><p>peri/post meno</p></li><li><p>(Premenopause → Perimenopause → Menopause → Postmenopause)</p></li><li><p>Menometrorrhagia (heavy, long, irregular bleeding)</p></li><li><p>infertility </p></li><li><p>Use color = highly vascular</p></li><li><p>Use sonohysterography </p></li></ul><p><strong>attached to the endometrium by a narrow or sometimes broad stalk</strong>.</p><p></p>
  • peri/post meno

  • (Premenopause → Perimenopause → Menopause → Postmenopause)

  • Menometrorrhagia (heavy, long, irregular bleeding)

  • infertility

  • Use color = highly vascular

  • Use sonohysterography

attached to the endometrium by a narrow or sometimes broad stalk.

Endometrial Poylp

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<ul><li><p><strong>POSTPARTUM patients</strong></p></li><li><p>PID pts</p></li><li><p>use of instrumentation causing infection </p><ul><li><p>fever / HIGH WBC</p></li><li><p>pelvic pain</p></li><li><p>low back pain</p></li><li><p>vaginal bleeding</p></li></ul></li></ul><p></p>
  • POSTPARTUM patients

  • PID pts

  • use of instrumentation causing infection

    • fever / HIGH WBC

    • pelvic pain

    • low back pain

    • vaginal bleeding

Endometritis

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<ul><li><p>results from </p><ul><li><p>trauma</p></li><li><p>surgery</p></li><li><p>D&amp;C</p></li><li><p>C-section</p></li><li><p>Postpartum curettage </p></li></ul></li></ul><p></p>
  • results from

    • trauma

    • surgery

    • D&C

    • C-section

    • Postpartum curettage

Synechiae

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<ul><li><p>MC gynecologic MALIGNANCY in North America</p></li><li><p>postmeno</p></li><li><p>estrogen-therapy</p></li><li><p>tamoxifen</p></li><li><p>pre meno </p><ul><li><p>anovulatory cycles</p></li><li><p>obesity </p></li></ul></li><li><p>pelvic pain </p></li></ul><p></p>
  • MC gynecologic MALIGNANCY in North America

  • postmeno

  • estrogen-therapy

  • tamoxifen

  • pre meno

    • anovulatory cycles

    • obesity

  • pelvic pain

Endometrial Carcinoma

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<ul><li><p>Happens when a <strong>dominant follicle fails to rupture</strong> or <strong>reseals (failed ovulation)</strong></p></li><li><p>Usually <strong>&gt;2.5 cm</strong>, typically <strong>up to 8–10 cm</strong></p></li><li><p>Simple cyst</p><ul><li><p>anechoic</p></li><li><p>clear thin walls</p></li><li><p>posterior enhancement</p><ul><li><p>asymptomatic</p></li><li><p>dull, adnexal pressure</p></li><li><p>adnexal pain</p><p></p></li></ul></li></ul></li></ul><p></p>
  • Happens when a dominant follicle fails to rupture or reseals (failed ovulation)

  • Usually >2.5 cm, typically up to 8–10 cm

  • Simple cyst

    • anechoic

    • clear thin walls

    • posterior enhancement

      • asymptomatic

      • dull, adnexal pressure

      • adnexal pain

Follicular cyst(Functional cyst)

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<p><strong>Ruptured dominant follicle</strong> normally becomes this.</p><ul><li><p>Complex cyst</p></li><li><p>thick walls</p></li><li><p><strong>1-  10 cm</strong></p></li><li><p><strong>“Ring of Fire”</strong></p></li><li><p>Internal echoes with cystic fluid / blood</p></li><li><p>irregular mens cycle</p></li><li><p>pain</p></li><li><p>mimic ectopic pregnancy</p></li><li><p>rupture</p></li></ul><p></p>

Ruptured dominant follicle normally becomes this.

  • Complex cyst

  • thick walls

  • 1- 10 cm

  • “Ring of Fire”

  • Internal echoes with cystic fluid / blood

  • irregular mens cycle

  • pain

  • mimic ectopic pregnancy

  • rupture

Corpus Luteum Cyst

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<p><strong>MC benign tumor of the ovary</strong></p><ul><li><p>abdominal pain / enlargement / pressure</p></li><li><p>complex solid mass with fat, teeth, hair, cartilage, bone</p></li><li><p>“tip of iceberg"</p></li></ul><p></p><p><u>Immature type-</u></p><ul><li><p>malignant, rare</p></li><li><p>10 - 20 yrs</p></li><li><p>AFP = HIGH</p></li></ul><p></p><p></p>

MC benign tumor of the ovary

  • abdominal pain / enlargement / pressure

  • complex solid mass with fat, teeth, hair, cartilage, bone

  • “tip of iceberg"

Immature type-

  • malignant, rare

  • 10 - 20 yrs

  • AFP = HIGH

Teratoma (Dermoid Cyst)

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<ul><li><p><strong>endocrine disorder</strong></p></li><li><p><strong>Chronic anovulation</strong></p></li><li><p>late teens - 20’s</p></li><li><p><strong>hirsutism</strong></p></li><li><p><strong>obesity </strong></p></li><li><p>infertility </p></li><li><p>irregular periods/no period</p></li><li><p>high LH</p></li><li><p>low FSH</p></li><li><p>Includes stein- leventhal syndrome</p></li><li><p>“string of pearls” appearance</p></li></ul><p>ENLARGED CYSTS</p>
  • endocrine disorder

  • Chronic anovulation

  • late teens - 20’s

  • hirsutism

  • obesity

  • infertility

  • irregular periods/no period

  • high LH

  • low FSH

  • Includes stein- leventhal syndrome

  • “string of pearls” appearance

ENLARGED CYSTS

PCOS (Polycystic Ovarian Syndrome)

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<p>2nd MC epithelial malignancy</p><p>1st MC is serous cystadenocarcinoma (also epithelial)  </p><ul><li><p>50 - 60 yrs</p></li></ul><p></p>

2nd MC epithelial malignancy

1st MC is serous cystadenocarcinoma (also epithelial)

  • 50 - 60 yrs

Endometroid

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<ul><li><p>elements from endocervix or bowel </p></li><li><p>100 LBS</p></li><li><p>often in 40-70 yrs old</p></li><li><p>benign, common</p></li><li><p>large complex mass</p></li><li><p>20-25%  of all benign ovarian neoplasms</p></li><li><p>5-10% of all malignant ovarian neoplasms</p></li><li><p>15-20% bilateral when malignant</p></li></ul><p></p>
  • elements from endocervix or bowel

  • 100 LBS

  • often in 40-70 yrs old

  • benign, common

  • large complex mass

  • 20-25% of all benign ovarian neoplasms

  • 5-10% of all malignant ovarian neoplasms

  • 15-20% bilateral when malignant

Mucinous Cystadenoma

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Definition: middle cycle pain

“Mittelshmerz”

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<p>MC ovarian MALIGNANCY</p><p></p>

MC ovarian MALIGNANCY

Serous Cystadenocarcinoma

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<ul><li><p>invades OUTSIDE THE UTERUS </p></li><li><p>15% are pre-meno</p></li><li><p><strong>chronic pelvic pain</strong></p></li><li><p><strong>DYSMENORRHEA = painful menses</strong></p></li><li><p>Infertility</p></li><li><p>painful sex</p></li><li><p>irregular bleeding</p></li><li><p>lower, abd pain</p></li></ul><p></p>
  • invades OUTSIDE THE UTERUS

  • 15% are pre-meno

  • chronic pelvic pain

  • DYSMENORRHEA = painful menses

  • Infertility

  • painful sex

  • irregular bleeding

  • lower, abd pain

Endometriosis

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<p>What is seen here</p>

What is seen here

IUCD (Intrauterine Contraceptive Device)

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<ul><li><p>40 - 70 yrs</p></li><li><p>leads to pseudomyxoma peritone (<strong>ascites </strong>thick)</p></li><li><p>large, multiloculated, <strong>THICK,</strong> irregular walls</p></li><li><p><strong>menopausal women 10% </strong></p></li><li><p><strong>pelvic pressure</strong></p></li><li><p><strong>pain when ruptured</strong></p></li><li><p>bloating</p></li><li><p>weight loss</p></li></ul><p></p>
  • 40 - 70 yrs

  • leads to pseudomyxoma peritone (ascites thick)

  • large, multiloculated, THICK, irregular walls

  • menopausal women 10%

  • pelvic pressure

  • pain when ruptured

  • bloating

  • weight loss

Mucinous Cystadenocarcinoma

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<p>“Chocolate cyst”</p><ul><li><p>heavy menses</p></li><li><p>well-defined</p></li><li><p>infertility</p></li><li><p>spotting</p></li><li><p>chronic lower back pain</p></li></ul><p></p>

“Chocolate cyst”

  • heavy menses

  • well-defined

  • infertility

  • spotting

  • chronic lower back pain

Endometrioma

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<ul><li><p><strong><mark data-color="yellow" style="background-color: yellow; color: inherit;"><u>4th leading cause of death</u></mark></strong></p></li><li><p>40 - 60 yrs</p></li><li><p>Family HX</p></li><li><p>Infertility </p></li><li><p>NULLIPARITY </p></li><li><p>abdominal pain</p></li><li><p>abdominal swelling</p></li><li><p>Indigestion</p></li><li><p>weight change</p></li><li><p>urinary urgency </p></li></ul><p></p>
  • 4th leading cause of death

  • 40 - 60 yrs

  • Family HX

  • Infertility

  • NULLIPARITY

  • abdominal pain

  • abdominal swelling

  • Indigestion

  • weight change

  • urinary urgency

Ovarian Carcinoma

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<p>MC in children + adolescents </p><ul><li><p>Rt ovary 3 x more likely</p><ul><li><p>Sudden, severe pain</p></li><li><p>nausea/vomiting</p></li><li><p>fever</p></li><li><p>palpable mass</p></li></ul></li></ul><p></p>

MC in children + adolescents

  • Rt ovary 3 x more likely

    • Sudden, severe pain

    • nausea/vomiting

    • fever

    • palpable mass

Ovarian Torsion

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<ul><li><p>Masculinization is taken over by anovulation</p></li><li><p>&lt; 30 yrs</p></li><li><p>LOW menses</p></li><li><p>NO menses</p></li><li><p>Produces Androgens</p></li><li><p>benign</p></li><li><p>Virilization (deep voice)</p></li></ul><p></p>
  • Masculinization is taken over by anovulation

  • < 30 yrs

  • LOW menses

  • NO menses

  • Produces Androgens

  • benign

  • Virilization (deep voice)

Arrhenoblastoma / Androblastoma

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<ul><li><p>sudden pelvic pain</p></li><li><p>causes internal bleeding into a follicular cyst or corpus luteum cyst</p><p></p></li></ul><ul><li><p><span>Hours/days after:</span></p><ul><li><p><span> highly echogenic due to clot formation</span><br></p></li></ul></li></ul><ul><li><p><span>Several days after</span></p><ul><li><p><span> increasingly complex appearance</span></p></li></ul></li></ul><p></p>
  • sudden pelvic pain

  • causes internal bleeding into a follicular cyst or corpus luteum cyst

  • Hours/days after:

    • highly echogenic due to clot formation

  • Several days after

    • increasingly complex appearance

Hemorrhagic Cyst

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<ul><li><p><strong><mark data-color="yellow" style="background-color: yellow; color: inherit;"><u>Wolfian duct remnants</u></mark></strong></p></li><li><p>10% of all adnexal masses</p></li><li><p>BROAD LIGAMENT location</p></li><li><p>benign cyst</p></li><li><p>20 -40 yrs</p></li><li><p>mesothelial/paranephric origin</p></li><li><p>asymptomatic </p><p></p></li></ul><p></p>
  • Wolfian duct remnants

  • 10% of all adnexal masses

  • BROAD LIGAMENT location

  • benign cyst

  • 20 -40 yrs

  • mesothelial/paranephric origin

  • asymptomatic

Para-ovarian Cyst

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<ul><li><p><strong>MC malignancy in CHILDHOOD </strong></p></li><li><p>high AFP and beta HCG</p></li></ul><p></p>
  • MC malignancy in CHILDHOOD

  • high AFP and beta HCG

Dysgerminoma

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<ul><li><p><span>BENIGN Small, solid, hypoechoic tumor</span><br><span>ASSOCIATED W/ MIEG'S</span><br><span>No internal cystic structures</span><br><span>(u) No calcifications, but possible</span><br><br><span>*Very similar to granulosa cell tumor</span></p></li></ul><p></p>
  • BENIGN Small, solid, hypoechoic tumor
    ASSOCIATED W/ MIEG'S
    No internal cystic structures
    (u) No calcifications, but possible

    *Very similar to granulosa cell tumor

Brenner's Tumor

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<p><span>Gastric adenocarcinoma with ovarian metastases</span></p>

Gastric adenocarcinoma with ovarian metastases

Krukenberg Tumor

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<ul><li><p><strong><mark data-color="yellow" style="background-color: yellow; color: inherit;"><u>Iatrogenic (treatment-caused) complication from ovulation induction </u></mark></strong></p></li><li><p>Mild - pelvic discomfort </p></li><li><p>Severe - severe pelvic pain + abdominal distention</p></li><li><p><strong>5-10 cm</strong></p></li></ul><p></p>
  • Iatrogenic (treatment-caused) complication from ovulation induction

  • Mild - pelvic discomfort

  • Severe - severe pelvic pain + abdominal distention

  • 5-10 cm

Ovarian Hyperstimulation Syndrome (OHSS)

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<ul><li><p>20-24 yrs</p></li><li><p>intense pelvic pain</p></li><li><p>dull, aching tenderness</p></li><li><p>fever</p></li><li><p>DISCHARGE</p></li><li><p>RUQ pain</p><ul><li><p>Risk factors</p><ul><li><p>early sex</p></li><li><p>multiple partners</p></li><li><p>STD</p></li><li><p>IUCD</p></li><li><p>douching</p></li><li><p>postsurgical/post abortion</p></li></ul></li></ul></li></ul><p></p>
  • 20-24 yrs

  • intense pelvic pain

  • dull, aching tenderness

  • fever

  • DISCHARGE

  • RUQ pain

    • Risk factors

      • early sex

      • multiple partners

      • STD

      • IUCD

      • douching

      • postsurgical/post abortion

Pelvic Inflammatory Disease (PID)

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  • PID caused by GONORRHEA

  • RUQ pain

  • related to PID

Fitz- Hugh Curtis Syndrome

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<ul><li><p>pelvic pain</p></li><li><p>fever</p></li><li><p>adnexal tenderness</p></li><li><p>PID complication </p></li></ul><p></p>
  • pelvic pain

  • fever

  • adnexal tenderness

  • PID complication

Tubo-ovarian Abscess

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  • secondary to PID, endometriosis

  • infertility

  • pelvic pain

Hydrosalpinx (Fluid in Fallopian tube)

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  • Chronic PID

  • SEVERE pelvic pain

  • fever

Pyosalpinx (Pus in fallopian tube)

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  • pelvic discomfort

  • fullness

  • LOW-grade fever

  • pelvic tenderness

  • related to PID

Salpingitis

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Total # of pregnancies (including current)

Gravidity

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Total # of births given

Parity

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3rd parameter after Gravity and Parity

Preterm & Stillborn

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4th parameter after Gravity and Parity

Losses & Abortions

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5 parameter after Gravidity and Parity

Living children

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1st Trimester is how long

13 weeks and 6 days

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2nd Trimester is how long

14 wks - 26 2ks + 6 days

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3rd Trimester is how long

27 wks → delivery

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< 90 BPM is considered what

Bradycardia

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> 160/170 BPM is considered what

Tachycardia

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What two measurements are taken in the 1st Trimester?

  • CRL (crown to rump)

  • Yolk Sac

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What is measured that is should be < 3.5 mm in the first trimester?

Nuchal Translucency

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Gestational Age (Menstrual age / LMP) is 2 weeks after or before the conceptual age (embryonic age)

If your gestational age is 8 weeks, the actual embryo is about 6 weeks old.

After

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Conception → 12 days is considered what

Zygote

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Implantation → 10 wks is considered what

Embryo

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10+ weeks → delivery is considered what

Fetus

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Menses cycle,

days 1-14 is considered what phase?

Menstruation phase

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Menses cycle,

days 5-14 is considered what

Proliferative Phase

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Proliferative phase is aligned with what ovarian phase?

  • see TRI -laminar sign (three line sign)

  • THIN ENDO

  • high estrogen

  • ovulation occurs on day 14

Follicular phase

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Menses cycle,

Days 15-28 is considered what phase?

Secretory phase

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The secretory phase is aligned with what ovarian phase?

  • ruptured follicle becomes Corpus luteum

  • produces progesterone

  • ENDO THICKENS

  • if no pregnancy, estrogen and progesterone DECLINE

Luteal phase

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The next period starts on _____ which is the end of the cycle

Day 28

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<p>Positive HCG, but there’s fluid + adnexal mass = </p>

Positive HCG, but there’s fluid + adnexal mass =

Ruptured ectopic pregnancy

90
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<p>What is 1?</p>

What is 1?

Intramural

91
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<p>what is 2?</p>

what is 2?

Pedunculated

92
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<p>What is 3?</p>

What is 3?

Intracavitary

93
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<p>what is 4?</p>

what is 4?

submucosal

94
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<p>what is 5?</p>

what is 5?

subserousal

95
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<p>How to write this ?</p>

How to write this ?

SAG UTERUS ML, Fibroid 2

intramural fibroid is seen within the myometrium of the uterus

96
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  • up to ~2.5 cm (normal)

  • aka graafian follice

  • normal ovulation

Dominant follicle

97
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Greater than what measurement is considered a surgical consult for an follicular cyst?

> 5 cm

98
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99
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Menstrual week 3 = how much beta hcg?

35-50 miu/ml

100
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Menstrual week 4, how much beta hcg?

45-426 miu/ml