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What do diuretics do?
make you urinate
what is one of the primary functions of the kidneys?
form and excrete waste products
how much urine is considered oliguria?
under 400 mL
Thiazide diuretics work on which area of the nephron?
distal tubule
Loop diuretics work on which area of the nephron?
Ascending loop of Henle
Prototype of the osmotic diuretics
Mannitol
What does anuria mean?
No urine
Prototype of the potassium sparing diuretics
Spironolactone
Prototype of the loop diuretics
Furosemide (Lasix)
What is the mechanism of action of the thiazide diuretics?
work in distal tubule and block reabsorption
Prototype of the thiazide diuretics
Hydrochlorothiazide
Do potassium sparing diuretics cause a large or small amount of diuresis?
small amount
Which diuretic is most helpful with increased intracranial pressure?
Mannitol
How much blood supply goes to the kidneys?
25%
Do loop diuretics cause a large or small amount of diuresis?
large amount
What is the functional unit of the kidney?
the nephron
In what organ is BUN made?
liver
Potassium sparing diuretics work on which area of the nephron?
distal tubule
What medications when given with furosemide increase the risk of nephrotoxicity?
aminoglycosides
cephalosporins
What is one of the main uses of thiazide diuretics?
hypertension
Side effects of thiazide diuretics
hypotension
weakness
dizziness
electrolyte disturbances
erectile dysfunction
Side effects of loop diuretics
fluid and electrolyte imbalances
ototoxicity
What is creatinine?
catabolic product of creatine phosphate (used in muscle contraction)
Side effects of potassium sparing diuretics
dizziness
headache
abdominal cramping
diarrhea
androgen receptor stimulation (testosterone effects)
hyperkalemia
tumorigenic
Tumorigenic
cause you to grow tumors
What GFR value shows healthy kidney function?
Over 60
Note 
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